Search Results - "BORSCHEL, Gregory H"

The use of the rat as a model for studying peripheral nerve regeneration and sprouting after complete and partial nerve injuries by Gordon, Tessa, Borschel, Gregory H.

“…Rat models of complete and partial injuries are the most frequently used models for analysis of the cellular and molecular processes of nerve regeneration and…”
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Electrical Stimulation to Promote Peripheral Nerve Regeneration by Willand, Michael P., Nguyen, May-Anh, Borschel, Gregory H., Gordon, Tessa

“…Peripheral nerve injury afflicts individuals from all walks of life. Despite the peripheral nervous system’s intrinsic ability to regenerate, many patients…”
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Advancing Nerve Regeneration: Translational Perspectives of Tacrolimus (FK506) by Daeschler, Simeon C, Feinberg, Konstantin, Harhaus, Leila, Kneser, Ulrich, Gordon, Tessa, Borschel, Gregory H

“…Peripheral nerve injuries have far-reaching implications for individuals and society, leading to functional impairments, prolonged rehabilitation, and…”
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The Degree of Facial Movement following Microvascular Muscle Transfer in Pediatric Facial Reanimation Depends on Donor Motor Nerve Axonal Density by Snyder-Warwick, Alison K., Fattah, Adel Y., Zive, Leanne, Halliday, William, Borschel, Gregory H., Zuker, Ronald M.

“…Free functional muscle transfer to the face is a standard of facial animation. The contralateral facial nerve, via a cross-face nerve graft, provides…”
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Effect of moist heat reprocessing of N95 respirators on SARS-CoV-2 inactivation and respirator function by Daeschler, Simeon C, Manson, Niclas, Joachim, Kariym, Chin, Alex W H, Chan, Katelyn, Chen, Paul Z, Tajdaran, Kiana, Mirmoeini, Kaveh, Zhang, Jennifer J, Maynes, Jason T, Zhang, Libo, Science, Michelle, Darbandi, Ali, Stephens, Derek, Gu, Frank, Poon, Leo L M, Borschel, Gregory H

“…Unprecedented demand for N95 respirators during the coronavirus disease 2019 (COVID-19) pandemic has led to a global shortage of these masks. We validated a…”
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Effectiveness and safety of the use of gracilis muscle for dynamic smile restoration in facial paralysis: A systematic review and meta-analysis by Roy, Mélissa, Corkum, Joseph P., Shah, Prakesh S., Borschel, Gregory H., Ho, Emily S., Zuker, Ronald M., Davidge, Kristen M.

“…Smiling is a fundamental component of social interactions. Significant challenges arise for patients with facial palsy. One of the key procedures for dynamic…”
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Foretinib mitigates cutaneous nerve fiber loss in experimental diabetic neuropathy by Daeschler, Simeon C., Zhang, Jennifer, Gordon, Tessa, Borschel, Gregory H., Feinberg, Konstantin

“…Diabetes is by far, the most common cause of neuropathy, inducing neurodegeneration of terminal sensory nerve fibers associated with loss of sensation,…”
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Processed allografts and type I collagen conduits for repair of peripheral nerve gaps by Whitlock, Elizabeth L., Tuffaha, Sami H., Luciano, Janina P., Yan, Ying, Hunter, Daniel A., Magill, Christina K., Moore, Amy M., Tong, Alice Y., Mackinnon, Susan E., Borschel, Gregory H.

“…Autografting is the gold standard in the repair of peripheral nerve injuries that are not amenable to end‐to‐end coaptation. However, because autografts result…”
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The Role of Sensory Innervation in Homeostatic and Injury-Induced Corneal Epithelial Renewal by Feinberg, Konstantin, Tajdaran, Kiana, Mirmoeini, Kaveh, Daeschler, Simeon C, Henriquez, Mario A, Stevens, Katelyn E, Mulenga, Chilando M, Hussain, Arif, Hamrah, Pedram, Ali, Asim, Gordon, Tessa, Borschel, Gregory H

“…The cornea is the window through which we see the world. Corneal clarity is required for vision, and blindness occurs when the cornea becomes opaque. The…”
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Enhancement of Facial Nerve Motoneuron Regeneration through Cross-Face Nerve Grafts by Adding End-to-Side Sensory Axons by Placheta, Eva, Wood, Matthew D., Lafontaine, Christine, Liu, Edward H., Hendry, J. Michael, Angelov, Doychin N., Frey, Manfred, Gordon, Tessa, Borschel, Gregory H.

“…In unilateral facial palsy, cross-face nerve grafts are used for emotional facial reanimation. Facial nerve regeneration through the grafts takes several…”
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Optical tissue clearing enables rapid, precise and comprehensive assessment of three-dimensional morphology in experimental nerve regeneration research by Daeschler, Simeon, Zhang, Jennifer, Gordon, Tessa, Borschel, Gregory

“…Morphological analyses are key outcome assessments for nerve regeneration studies but are historically limited to tissue sections. Novel optical tissue…”
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Nerve cross-bridging to enhance nerve regeneration in a rat model of delayed nerve repair by Gordon, Tessa, Hendry, Michael, Lafontaine, Christine A, Cartar, Holliday, Zhang, Jennifer J, Borschel, Gregory H

“…There are currently no available options to promote nerve regeneration through chronically denervated distal nerve stumps. Here we used a rat model of delayed…”
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Experimental and clinical evidence for use of decellularized nerve allografts in peripheral nerve gap reconstruction by Szynkaruk, Mark, Kemp, Stephen W P, Wood, Matthew D, Gordon, Tessa, Borschel, Gregory H

“…Despite the inherent capability for axonal regeneration, recovery following severe peripheral nerve injury remains unpredictable and often very poor. Surgeons…”
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Management of Bilateral Facial Palsy by Domeshek, Leahthan F., MD, Zuker, Ronald M., MD, FRCS, Borschel, Gregory H., MD

“…Bilateral facial paralysis is a rare entity that occurs in both pediatric and adult patients and can have congenital or acquired causes. When paralysis does…”
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Schwann cells seeded in acellular nerve grafts improve functional recovery by Jesuraj, Nithya J., Santosa, Katherine B., Macewan, Matthew R., Moore, Amy M., Kasukurthi, Rahul, Ray, Wilson Z., Flagg, Eric R., Hunter, Daniel A., Borschel, Gregory H., Johnson, Philip J., Mackinnon, Susan E., Sakiyama-Elbert, Shelly E.

“…ABSTRACT Introduction: This study evaluated whether Schwann cells (SCs) from different nerve sources transplanted into cold‐preserved acellular nerve grafts…”
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A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair by Daeschler, Simeon C, So, Katelyn J W, Feinberg, Konstantin, Manoraj, Marina, Cheung, Jenny, Zhang, Jennifer, Mirmoeini, Kaveh, Santerre, J Paul, Gordon, Tessa, Borschel, Gregory H

“…JOURNAL/nrgr/04.03/01300535-202501000-00036/figure1/v/2024-05-14T021156Z/r/image-tiff Axonal regeneration following surgical nerve repair is slow and often…”
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Corneal Nerve Assessment by Aesthesiometry: History, Advancements, and Future Directions by Crabtree, Jordan R, Tannir, Shadia, Tran, Khoa, Boente, Charline S, Ali, Asim, Borschel, Gregory H

“…The measurement of corneal sensation allows clinicians to assess the status of corneal innervation and serves as a crucial indicator of corneal disease and eye…”
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Affinity-based release of glial-derived neurotrophic factor from fibrin matrices enhances sciatic nerve regeneration by Wood, Matthew D., Moore, Amy M., Hunter, Daniel A., Tuffaha, Sami, Borschel, Gregory H., Mackinnon, Susan E., Sakiyama-Elbert, Shelly E.

“…Glial-derived neurotrophic factor (GDNF) promotes both sensory and motor neuron survival. The delivery of GDNF to the peripheral nervous system has been shown…”
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Outcomes after Anterior Interosseous Nerve to Ulnar Motor Nerve Transfer by Gross, Jeffrey N., Dawson, Steven E., Wu, Gerald J., Loewenstein, Scott, Borschel, Gregory H., Adkinson, Joshua M.

“…Abstract Background  Ulnar nerve lesions proximal to the elbow can result in loss of intrinsic muscle function of the hand. The anterior interosseous nerve…”
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Biohacking Nerve Repair: Novel Biomaterials, Local Drug Delivery, Electrical Stimulation, and Allografts to Aid Surgical Repair by Crabtree, Jordan R, Mulenga, Chilando M, Tran, Khoa, Feinberg, Konstantin, Santerre, J Paul, Borschel, Gregory H

“…The regenerative capacity of the peripheral nervous system is limited, and peripheral nerve injuries often result in incomplete healing and poor outcomes even…”
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