Search Results - "BORRIE, Michael J"

Motor cortex and gait in mild cognitive impairment: a magnetic resonance spectroscopy and volumetric imaging study by ANNWEILER, Cedric, BEAUCHET, Olivier, BARTHA, Robert, WELLS, Jennie L, BORRIE, Michael J, HACHINSKI, Vladimir, MONTERO-ODASSO, Manuel

“…Gait disorders are common in the course of dementia, even at the stage of mild cognitive impairment, owing to probable changes in higher levels of motor…”
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Spontaneous low frequency BOLD signal variations from resting-state fMRI are decreased in Alzheimer disease by Kazemifar, Samaneh, Manning, Kathryn Y, Rajakumar, Nagalingam, Gómez, Francisco A, Soddu, Andrea, Borrie, Michael J, Menon, Ravi S, Bartha, Robert

“…Previous studies have demonstrated altered brain activity in Alzheimer's disease using task based functional MRI (fMRI), network based resting-state fMRI, and…”
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Quantitative gait analysis under dual-task in older people with mild cognitive impairment: a reliability study by Montero-Odasso, Manuel, Casas, Alvaro, Hansen, Kevin T, Bilski, Patricia, Gutmanis, Iris, Wells, Jennie L, Borrie, Michael J

“…Reliability of quantitative gait assessment while dual-tasking (walking while doing a secondary task such as talking) in people with cognitive impairment is…”
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Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease by Penner, Jacob, Rupsingh, Raul, Smith, Matthew, Wells, Jennie L., Borrie, Michael J., Bartha, Robert

“…Galantamine is a cholinesterase inhibitor and allosteric potentiating ligand modulating presynaptic nicotinic acetylcholine receptors that is used in the…”
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Association of Dual-Task Gait With Incident Dementia in Mild Cognitive Impairment: Results From the Gait and Brain Study by Montero-Odasso, Manuel M, Sarquis-Adamson, Yanina, Speechley, Mark, Borrie, Michael J, Hachinski, Vladimir C, Wells, Jennie, Riccio, Patricia M, Schapira, Marcelo, Sejdic, Ervin, Camicioli, Richard M, Bartha, Robert, McIlroy, William E, Muir-Hunter, Susan

“…Gait performance is affected by neurodegeneration in aging and has the potential to be used as a clinical marker for progression from mild cognitive impairment…”
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Can cognitive enhancers reduce the risk of falls in older people with mild cognitive impairment? A protocol for a randomised controlled double blind trial by Montero-Odasso, Manuel, Wells, Jennie L, Borrie, Michael J, Speechley, Mark

“…Older adults with cognitive problems have a higher risk of falls, at least twice that of cognitively normal older adults. The consequences of falls in this…”
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Reduced Hippocampal Glutamate and Posterior Cingulate N-Acetyl Aspartate in Mild Cognitive Impairment and Alzheimer's Disease Is Associated with Episodic Memory Performance and White Matter Integrity in the Cingulum: A Pilot Study by Wong, Dickson, Atiya, Samir, Fogarty, Jennifer, Montero-Odasso, Manuel, Pasternak, Stephen H, Brymer, Chris, Borrie, Michael J, Bartha, Robert

“…Identification of biological changes underlying the early symptoms of Alzheimer's disease (AD) will help to identify and stage individuals prior to symptom…”
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Disentangling Cognitive-Frailty: Results From the Gait and Brain Study by Montero-Odasso, Manuel M, Barnes, Brittany, Speechley, Mark, Muir Hunter, Susan W, Doherty, Timothy J, Duque, Gustavo, Gopaul, Karen, Sposato, Luciano A, Casas-Herrero, Alvaro, Borrie, Michael J, Camicioli, Richard, Wells, Jennie L

“…Cognitive-frailty, defined as the presence of both frailty and cognitive impairment, is proposed as a distinctive entity that predicts dementia. However, it…”
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Shifting efficacy, distribution of attention and controlled processing in two subtypes of mild cognitive impairment: Response time performance and intraindividual variability on a visual search task by McLaughlin, Paula M., Borrie, Michael J., Murtha, Susan J. E.

“…A visual search task was used to investigate how visual attention and intraindividual variability changes with mild cognitive impairment (MCI). Specifically,…”
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Frailty is associated with postoperative complications in older adults with medical problems by Dasgupta, Monidipa, Rolfson, Darryl B, Stolee, Paul, Borrie, Michael J, Speechley, Mark

“…Abstract We sought to test whether frailty may be predictive of operative risk in older adults with medical problems. One hundred and twenty-five patients at…”
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A "Patient Preference" Model of Recruitment for Research from Primary-Care-Based Memory Clinics: A Promising New Approach by Lee, Linda, Hillier, Loretta M, Patel, Tejal, Gregg, Susie, Hickman, Kathy, Lu, Stephanie K, Lee, Michael, Borrie, Michael J

“…Recruiting persons with dementia for clinical trials can be challenging. Building on a guide initially developed to assist primary-care-based memory clinics in…”
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Elicited clinician knowledge did not improve dementia risk prediction in individuals with mild cognitive impairment by Wang, Meng, Chekouo, Thierry, Ismail, Zahinoor, Forkert, Nils D., Hogan, David B., Ganesh, Aravind, Camicioli, Richard, Seitz, Dallas, Borrie, Michael J., Hsiung, Ging-Yuek Robin, Masellis, Mario, Moorhouse, Paige, Tartaglia, Carmela, Smith, Eric E., Sajobi, Tolulope T.

“…This study aims to develop and validate a Bayesian risk prediction model that combines research cohort data with elicited expert knowledge to predict dementia…”
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Expert elicitation of risk factors for progression to dementia in individuals with mild cognitive impairment by Wang, Meng, Sajobi, Tolulope T, Hogan, David B, Ganesh, Aravind, Seitz, Dallas P, Chekouo, Thierry, Forkert, Nils D, Borrie, Michael J, Camicioli, Richard, Hsiung, Ging-Yuek Robin, Masellis, Mario, Moorhouse, Paige, Tartaglia, Maria Carmela, Ismail, Zahinoor, Smith, Eric E

“…This study assesses experts' beliefs about important predictors of developing dementia in persons with mild cognitive impairment (MCI). Structured expert…”
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Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology by Xhima, Kristiana, Ottoy, Julie, Gibson, Erin, Zukotynski, Katherine, Scott, Christopher, Feliciano, Ginelle J., Adamo, Sabrina, Kuo, Phillip H., Borrie, Michael J., Chertkow, Howard, Frayne, Richard, Laforce, Robert, Noseworthy, Michael D., Prato, Frank S., Sahlas, Demetrios J., Smith, Eric E., Sossi, Vesna, Thiel, Alexander, Soucy, Jean‐Paul, Tardif, Jean‐Claude, Goubran, Maged, Black, Sandra E., Ramirez, Joel

“…INTRODUCTION Cerebral small vessel disease (SVD) and amyloid beta (Aβ) pathology frequently co‐exist. The impact of concurrent pathology on the pattern of…”
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Primary Care-Based Memory Clinics: Expanding Capacity for Dementia Care by Lee, Linda, Hillier, Loretta M, Heckman, George, Gagnon, Micheline, Borrie, Michael J, Stolee, Paul, Harvey, David

“…The implementation in Ontario of 15 primary-care-based interprofessional memory clinics represented a unique model of team-based case management aimed at…”
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Automated algorithm to measure changes in medial temporal lobe volume in Alzheimer disease by Kazemifar, Samaneh, Drozd, John J., Rajakumar, Nagalingam, Borrie, Michael J., Bartha, Robert

“…•Fully automated medial temporal lobe (MTL) atrophy measurement.•Significant MTL atrophy over 24 months in NEC, MCI, and AD groups.•A significant difference in…”
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Updated Inventory and Projected Requirements for Specialist Physicians in Geriatrics by Basu, Monisha, Cooper, Tracy, Kay, Kelly, Hogan, David B, Morais, José A, Molnar, Frank, Lam, Robert E, Borrie, Michael J

“…The predicted growth of Canadians aged 65+ and the resultant rise in the demand for specialized geriatric services (SGS) requires physician resource planning…”
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State of the art in geriatric rehabilitation. Part I: Review of frailty and comprehensive geriatric assessment by Wells, Jennie L, Seabrook, Jamie A, Stolee, Paul, Borrie, Michael J, Knoefel, Frank

“…Wells JL, Seabrook JA, Stolee P, Borrie MJ, Knoefel F. State of the art in geriatric rehabilitation. Part I: Review of frailty and comprehensive geriatric…”
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Differences in rate of functional decline across three dementia types by Gill, Dawn P, Hubbard, Rebecca A, Koepsell, Thomas D, Borrie, Michael J, Petrella, Robert J, Knopman, David S, Kukull, Walter A

“…Abstract Background The purpose of this study was to estimate differences in rates of functional decline in Alzheimer's disease (AD), dementia with Lewy bodies…”
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Reduced N-acetylaspartate to creatine ratio in the posterior cingulate correlates with cognition in Alzheimer's disease following four months of rivastigmine treatment by Penner, Jacob, Wells, Jennie L, Borrie, Michael J, Woolmore-Goodwin, Sarah M, Bartha, Robert

“…To determine whether 4 months of rivastigmine treatment would result in metabolic changes and whether metabolic changes correlate with changes in cognition in…”
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