Search Results - "BORRELL, J. I"

Porphycenes: facts and prospects in photodynamic therapy of cancer by Stockert, J C, Cañete, M, Juarranz, A, Villanueva, A, Horobin, R W, Borrell, J I, Teixidó, J, Nonell, S

“…The photodynamic process induces cell damage and death by the combined effect of a photosensitizer (PS), visible light, and molecular oxygen, which generate…”
Get more information

Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma by Balsas, P, Esteve-Arenys, A, Roldán, J, Jiménez, L, Rodríguez, V, Valero, J G, Chamorro-Jorganes, A, de la Bellacasa, R Puig, Teixidó, J, Matas-Céspedes, A, Moros, A, Martínez, A, Campo, E, Sáez-Borderías, A, Borrell, J I, Pérez-Galán, P, Colomer, D, Roué, G

“…Pharmacological inhibition of B cell receptor (BCR) signaling has recently emerged as an effective approach in a wide range of B lymphoid neoplasms. However,…”
Get full text

Necrotic cell death induced by photodynamic treatment of human lung adenocarcinoma A-549 cells with palladium(II)-tetraphenylporphycene by Cañete, M, Ortega, C, Gavaldá, A, Cristobal, J, Juarranz, A, Nonell, S, Teixidó, J, Borrell, J I, Villanueva, A, Rello, S, Stockert, J C

“…In this study we describe photodamaging and photokilling effects of palladium(II)-tetraphenylporphycene (PdTPPo) (previously incorporated into…”
Get more information

Recent advances in combinatorial chemistry applied to development of anti-HIV drugs by Pettersson, S, Clotet-Codina, I, Esté, J A, Borrell, J I, Teixidó, J

“…A compilation of combinatorial chemistry techniques applied to anti-HIV drug development is presented in this review. This synthetic strategy together with…”
Get more information

Selective Hydrolysis of 2,4-Diaminopyrimidine Systems:  A Theoretical and Experimental Insight into an Old Rule by Teixidó, J, Borrell, J. I, Colominas, C, Deupí, X, Matallana, J. L, Falcó, J. L, Martinez-Teipel, B

“…Hydrolysis of the amino groups in condensed 2,4-diaminopyrimidine systems (1) has been used as a common method for the synthesis of oxo-substituted…”
Get full text

Synthesis and Biological Activity of 7-Oxo Substituted Analogues of 5-Deaza-5,6,7,8-tetrahydrofolic Acid (5-DATHF) and 5,10-Dideaza-5,6,7,8-tetrahydrofolic Acid (DDATHF) by Borrell, José I, Teixidó, Jordi, Matallana, Josep Lluís, Martínez-Teipel, Blanca, Colominas, Carles, Costa, Marta, Balcells, Merche, Schuler, Elisabeth, Castillo, María José

“…We recently described the syntheses of 12a−c, 4-amino-7-oxo substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid (5-DATHF), and…”
Get full text

Synthesis and Biological Activity of 4-Amino-7-oxo-Substituted Analogues of 5-Deaza-5,6,7,8-tetrahydrofolic Acid and 5,10-Dideaza-5,6,7,8-tetrahydrofolic Acid by Borrell, José I, Teixidó, Jordi, Martínez-Teipel, Blanca, Matallana, Josep Lluís, Copete, M. Teresa, Llimargas, Ana, García, Eva

“…The 4-amino-7-oxo-substituted analogues of 5-deaza-5,6,7,8-tetrahydrofolic acid (5-DATHF) and 5,10-dideaza-5,6,7,8-tetrahydrofolic acid (DDATHF) were…”
Get full text

Photosensitizing properties of palladium-tetraphenylporphycene on cultured tumour cells by Cañete, M, Ortiz, A, Juarranz, A, Villanueva, A, Nonell, S, Borrell, J I, Teixidó, J, Stockert, J C

“…In this study we describe photokilling properties and effects on the mitotic index (MI) of cultured HeLa cells induced by palladium(II)-tetraphenylporphycene…”
Get more information

Primary, secondary, and tertiary structure of the core of a histone H1-like protein from the sperm of Mytilus by JUTGLAR, L, BORRELL, J. I, AUSIO, J

“…We have analyzed the structure of the trypsin-resistant core of the protein PL-II* of the sperm from Mytilus californianus. The peptide has a molecular mass of…”
Get full text

Uptake of tetraphenylporphycene and its photoeffects on actin and cytokeratin elements of HeLa cells by Cañete, M, Lapeña, M, Juarranz, A, Vendrell, V, Borrell, J I, Teixidó, J, Nonell, S, Villanueva, A

“…In the present work we have continued our studies in the photobiological properties of the 2,7,12,17-tetraphenylporphycene (TPPo). In particular, the uptake,…”
Get more information

Photodamaging effects of tetraphenylporphycene in a human carcinoma cell line by Villanueva, A, Cañete, M, Nonell, S, Borrell, J I, Teixidó, J, Juarranz, A

“…The photosensitizing effects of tetraphenylporphycene (TPPo) and light on HeLa cells, with emphasis on cell viability and the microtubular network, have been…”
Get more information

A Diversity-Oriented, Microwave-Assisted Synthesis of 4-oxo and 4-chloropyrido[2,3-d]pyrimidin-7(8H)-ones by Mont, N., Fernández-Megido, L., Teixidó, J., Kappe, C. O., Borrell, J. I.

“…A microwave‐assisted protocol for the synthesis of 4‐oxo and 4‐chloropyrido[2,3‐d]pyrimidin‐7(8H)‐ones, 13 and 9 respectively, bearing a carbon substituent at…”
Get full text

Crystal structure, spectroscopic study, molecular modeling, and in vitro antimicrobial activity testing of 2,2'-thiobis[4,6-diphenylpyridine-3-carbonitrile] by VICTORY, P, BUSQUETS, N, BORRELL, J. I, SANCHEZ, I, TEIXIDO, J, SERRA, B, ALVAREZ-LARENA, A, PINIELLA, J. F, GUINEA, J, GARCIA, J

Get full text

Solid phase vs. solution phase differential behavior: formation of a salicylate structure from a malondialdehyde moiety by Borrell, J I, Teixidó, J, Schuler, E, Michelotti, E L

“…Treatment of 2, solid supported synthetic equivalent of 3-formylchromone (4), and ethyl acetoacetate affords the salicylate structure 8 instead of the…”
Get full text

A simple synthesis of 2-methoxypyridine-3-carbonitriles by VICTORY, P, BORRELL, J. I, VIDAL-FERRAN, A

Get full text

Synthesis of 4-amino-8-cyanoquinazolines from enones and enals by VICTORY, P, BORRELL, J. I, VIDAL-FERRAN, A, MONTENEGRO, E, JIMENO, M. L

Get full text

A synthesis of 1,2,3,4-tetrahydro-1,6-naphthyridines by VICTORY, P. J, TEIXIDO, J, BORRELL, J. I

Get full text

Synthesis of 2-cyanamino-4,6-diphenyl-pyridine-3-carbonitrile by VICTORY, P, BORRELL, J. I, CIRUJEDA, J, VIDAL-FERRAN, A

Get full text

A three-component synthesis of pyrido[2,3- d]pyrimidines by Mont, Núria, Teixidó, Jordi, Borrell, José I, Kappe, C.Oliver

“…A new, high yield multicomponent reaction providing multifunctionalized pyrido[2,3- d]pyrimidines in a microwave-assisted one-pot cyclocondensation of…”
Get full text

Diethyl 2,7-Dibromo-4H,5H- thieno[3,2-b:4,5-b‘]dipyrrole-3,6- dicarboxylate:  A Key Intermediate for a Diversity Oriented Synthesis of 2,7,12,17-Tetraarylporphycenes by Arad, Ofir, Morros, Jordi, Batllori, Xavier, Teixidó, Jordi, Nonell, Santiago, Borrell, José I

“…A new Suzuki-based strategy for the synthesis of 4,4‘-diaryl (or heteroaryl)-substituted 2,2‘-bipyrroles (10), precursors of 2,7,12,17-tetraaryl (or…”
Get full text