Search Results - "BORRE, Tony"

A small-molecule inhibitor of Bcl-XL potentiates the activity of cytotoxic drugs in vitro and in vivo by SHOEMAKER, Alex R, OLEKSIJEW, Anatol, MARSH, Kennan, MCCLELLAN, William, NELLANS, Hugh, NG, Shichung, NIMMER, Paul, O'CONNOR, Jacqueline M, OLTERSDORF, Tilman, WEIGUO QING, WANG SHEN, STAVROPOULOS, Jason, BAUCH, Joy, TAHIR, Stephen K, BAOLE WANG, WARNER, Robert, HAICHAO ZHANG, FESIK, Stephen W, ROSENBERG, Saul H, ELMORE, Steven W, BELLI, Barbara A, BORRE, Tony, BRUNCKO, Milan, DECKWIRTH, Thomas, FROST, David J, JARVIS, Ken, JOSEPH, Mary K

“…Inhibition of the prosurvival members of the Bcl-2 family of proteins represents an attractive strategy for the treatment of cancer. We have previously…”
Get full text

Rational Design of Diflunisal Analogues with Reduced Affinity for Human Serum Albumin by Mao, Hongyuan, Hajduk, Philip J, Craig, Richard, Bell, Randy, Borre, Tony, Fesik, Stephen W

“…Many lead compounds bind to serum albumin and exhibit markedly reduced efficacy in vivo as compared to their potency in vitro. To aid in the design of…”
Get full text