Search Results - "BOROWIEC, J. A"

Nucleolin inhibits Hdm2 by multiple pathways leading to p53 stabilization by SAXENA, A, RORIE, C. J, DIMITROVA, D, DANIELY, Y, BOROWIEC, J. A

“…Nucleolin is a c-Myc-induced gene product with defined roles in ribosomal RNA processing and the inhibition of chromosomal DNA replication following stress…”
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Human replication protein A binds single-stranded DNA in two distinct complexes by BLACKWELL, L. J, BOROWIEC, J. A

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Localized melting and structural changes in the SV40 origin of replication induced by T‐antigen by Borowiec, J. A., Hurwitz, J.

“…Replication of simian virus 40 (SV40) DNA is dependent upon the binding of the viral T‐antigen to the SV40 origin of replication. Structural changes in the…”
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5‘ → 3‘ Molecular Polarity of Human Replication Protein A (hRPA) Binding to Pseudo-Origin DNA Substrates by Iftode, Cristina, Borowiec, James A

“…Human replication protein A (hRPA) was previously seen to efficiently bind a 48 bp simian virus 40 (SV40) “pseudo-origin” (PO) substrate that mimics a DNA…”
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The simian virus 40 T antigen double hexamer assembles around the DNA at the replication origin by DEAN, F. B, BOROWIEC, J. A, EKI, T, HURWITZ, J

“…An initial step in the replication of simian virus (SV40) DNA is the ATP-dependent formation of a double hexamer of the SV40 large tumor (T) antigen at the…”
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Single-stranded-DNA binding alters human replication protein A structure and facilitates interaction with DNA-dependent protein kinase by Blackwell, Leonard J., Borowiec, James A., Mastrangelo, Iris A.

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Replication of Simian Virus 40 Origin-Containing DNA in vitro with Purified Proteins by Wobbe, C. Richard, Weissbach, Lawrence, Borowiec, James A., Dean, Frank B., Murakami, Yasufumi, Bullock, Peter, Hurwitz, Jerard

“…Simian virus 40 (SV40) DNA replication dependent on the SV40 origin of replication and the SV40 large tumor (T) antigen has been reconstituted in vitro with…”
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Dimerization of simian virus 40 T-antigen hexamers activates T-antigen DNA helicase activity by Smelkova, N V, Borowiec, J A

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ATP stimulates the binding of simian virus 40 (SV40) large tumor antigen to the SV40 origin of replication by BOROWIEC, J. A, HURWITZ, J

“…Simian virus 40 (SV40) large tumor antigen (T antigen) binds to two contiguous sites at the SV40 origin of replication. Of these two sites, I and II, only site…”
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Binding and unwinding--how T antigen engages the SV40 origin of DNA replication by Borowiec, J A, Dean, F B, Bullock, P A, Hurwitz, J

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Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteins by Gillette, T.G, Lusky, M, Borowiec, J.A

“…Chemical and enzymatic probing techniques were used to examine the interaction of the bovine papillomavirus type 1 E1 and E2 proteins with the viral origin of…”
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Denaturation of the simian virus 40 origin of replication mediated by human replication protein A by Iftode, Cristina, Borowiec, James A.

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Replication protein A (RPA): the eukaryotic SSB by Iftode, C, Daniely, Y, Borowiec, J A

“…Replication protein A (RPA) is a heterotrimeric single-stranded DNA-binding protein that is highly conserved in eukaryotes. RPA plays essential roles in many…”
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Inhibition of structural changes in the simian virus 40 core origin of replication by mutation of essential origin sequences by BOROWIEC, J. A

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Differential induction of structural changes in the simian virus 40 origin of replication by T antigen by BOROWIEC, J. A, DEAN, F. B, HURWITZ, J

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DNA supercoiling promotes formation of a bent repression loop in lac DNA by Borowiec, J A, Zhang, L, Sasse-Dwight, S, Gralla, J D

“…Titration experiments on supercoiled lac DNA show that one repressor tetramer can bind simultaneously to the primary lac operator and to the very weak lac…”
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Simian Virus 40 Large Tumor Antigen Requires Three Core Replication Origin Domains for DNA Unwinding and Replication in vitro by Dean, Frank B., Borowiec, James A., Ishimi, Yukio, Deb, Sumitra, Tegtmeyer, Peter, Hurwitz, Jerard

“…Simian virus 40 (SV40) large tumor antigen (T antigen) unwinds DNA containing the SV40 origin of replication. The origin requirement for unwinding can be…”
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Distinct roles of two binding sites for the bovine papillomavirus (BPV) E2 transactivator on BPV DNA replication by Gillette, T.G, Borowiec, J.A

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Strand and face: the topography of interactions between the SV40 origin of replication and T‐antigen during the initiation of replication by SenGupta, D.J., Borowiec, J.A.

“…The mechanism by which a replicator (origin of replication) becomes denatured during the initiation of replication is not understood for any prokaryotic or…”
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Formation of a Complex between Nucleolin and Replication Protein A after Cell Stress Prevents Initiation of DNA Replication by Daniely, Yaron, Borowiec, James A.

“…We used a biochemical screen to identify nucleolin, a key factor in ribosome biogenesis, as a high-affinity binding partner for the heterotrimeric human…”
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