Search Results - "BOROOJERDI, Babak"
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Does the MDS-UPDRS provide the precision to assess progression in early Parkinson’s disease? Learnings from the Parkinson’s progression marker initiative cohort
Published in Journal of neurology (01-08-2019)“…Objectives Developing disease modifying therapies for Parkinson’s disease (PD) calls for outcome measurement strategies focused on characterizing early stage…”
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Feasibility of large-scale deployment of multiple wearable sensors in Parkinson's disease
Published in PloS one (20-12-2017)“…Wearable devices can capture objective day-to-day data about Parkinson's Disease (PD). This study aims to assess the feasibility of implementing wearable…”
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Rotigotine effects on early morning motor function and sleep in Parkinson's disease: A double-blind, randomized, placebo-controlled study (RECOVER)
Published in Movement disorders (01-01-2011)“…In a multinational, double‐blind, placebo‐controlled trial (NCT00474058), 287 subjects with Parkinson's disease (PD) and unsatisfactory early‐morning motor…”
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Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy, randomised controlled trial
Published in Lancet neurology (01-06-2007)“…Summary Background Continuous dopaminergic drug delivery is an unmet medical need in advanced Parkinson's disease. The aim of this trial—Clinical Efficacy of…”
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Rotigotine transdermal patch in early Parkinson's disease: A randomized, double-blind, controlled study versus placebo and ropinirole
Published in Movement disorders (15-12-2007)“…Rotigotine is a new, non‐ergot dopamine agonist formulated in a transdermal delivery system. The present study was to investigate the efficacy and safety of…”
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Early consolidation in human primary motor cortex
Published in Nature (London) (07-02-2002)“…Behavioural studies indicate that a newly acquired motor skill is rapidly consolidated from an initially unstable state to a more stable state, whereas…”
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Maintenance of zilucoplan efficacy in patients with generalised myasthenia gravis up to 24 weeks: a model-informed analysis
Published in Therapeutic advances in neurological disorders (01-01-2024)“…Clinical efficacy of zilucoplan has been demonstrated in a 12-week, placebo-controlled, phase III study in patients with acetylcholine receptor…”
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2997 Corticosteroid dose tapering in patients with generalised myasthenia gravis on zilucoplan: interim analysis of RAISE-XT
Published in BMJ neurology open (01-08-2024)“…BackgroundIn the Phase 3 RAISE study (NCT04115293), zilucoplan significantly improved myasthenia gravis (MG)-specific outcomes in patients with acetylcholine…”
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Effects of low-frequency transcranial magnetic stimulation on motor excitability and basic motor behavior
Published in Clinical neurophysiology (01-06-2000)“…To explore effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex (M1) on motor excitability and basic motor…”
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Long-term safety and efficacy of zilucoplan in patients with generalized myasthenia gravis: interim analysis of the RAISE-XT open-label extension study
Published in Therapeutic advances in neurological disorders (01-01-2024)“…Generalized myasthenia gravis (gMG) is a chronic, unpredictable disease associated with high treatment and disease burdens, with a need for more effective and…”
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Role of the human motor cortex in rapid motor learning
Published in Experimental brain research (01-02-2001)“…Recent studies suggest that the human primary motor cortex (M1) is involved in motor learning, but the nature of that involvement is not clear. Here,…”
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Development and early qualitative evidence of two novel patient-reported outcome instruments to assess daily functioning in people with early-stage Parkinson’s
Published in Journal of patient-reported outcomes (20-04-2023)“…Background Previous research on concepts that are important to people living with early-stage Parkinson’s indicated that ‘ functional ’ slowness, fine motor…”
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Transdermal rotigotine for the perioperative management of Parkinson’s disease
Published in Journal of Neural Transmission (01-07-2010)“…Continuous delivery of antiparkinsonian medication during a perioperative period is desirable to avoid ‘off’-symptom complications in surgical patients with…”
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The dorsal premotor cortex orchestrates concurrent speech and fingertapping movements
Published in The European journal of neuroscience (01-05-2009)“…Human speech and hand use both involve highly specialized complex movement patterns. Whereas previous studies in detail characterized the cortical motor…”
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Effects of long-term practice and task complexity in musicians and nonmusicians performing simple and complex motor tasks: Implications for cortical motor organization
Published in Human brain mapping (01-07-2005)“…Motor practice induces plastic changes within the cortical motor system. Whereas rapidly evolving changes of cortical motor representations were the subject of…”
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Interhemispheric imbalance during visuospatial attention investigated by unilateral and bilateral TMS over human parietal cortices
Published in Brain research (09-02-2006)“…We used single-pulse transcranial magnetic stimulation (TMS) to study visuospatial attention. TMS was applied over one hemisphere, or simultaneously over both…”
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Cortical excitability changes induced by deafferentation of the contralateral hemisphere
Published in Brain (London, England : 1878) (01-06-2002)“…Short-term deprivation of sensory input by ischaemic nerve block (INB) leads to functional reorganization in the deafferented motor cortex. Here, we show that…”
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Motor representation in patients rapidly recovering after stroke: a functional magnetic resonance imaging and transcranial magnetic stimulation study
Published in Clinical neurophysiology (01-12-2003)“…Objective: Neuroimaging studies have suggested an evolution of the brain activation pattern in the course of motor recovery after stroke. Initially poor motor…”
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Repetitive transcranial magnetic stimulation of the parietal cortex transiently ameliorates phantom limb pain-like syndrome
Published in Clinical neurophysiology (01-08-2003)“…Objective: Phantom pain is linked to a reorganization of the partially deafferented sensory cortex. In this study we have investigated whether the pain…”
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Shift in sound localization induced by rTMS of the posterior parietal lobe
Published in Neuropsychologia (2004)“…Neuroimaging studies in human subjects and single-unit recordings in monkeys have suggested the primate posterior parietal cortex (PPC) to be involved in…”
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