Search Results - "BORN, T. L"

Interleukin 18 is a primary mediator of the inflammation associated with dextran sulphate sodium induced colitis: blocking interleukin 18 attenuates intestinal damage by Sivakumar, P V, Westrich, G M, Kanaly, S, Garka, K, Born, T L, Derry, J M J, Viney, J L

“…Background and aims: Persistent inflammation observed in inflammatory bowel disease may be the consequence of an increased or aberrant immune response to…”
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The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins by Baranova, Ancha, Ivanov, Dmitry, Petrash, Nadezda, Pestova, Anya, Skoblov, Mikhail, Kelmanson, Ilya, Shagin, Dmitry, Nazarenko, Svetlana, Geraymovych, Elena, Litvin, Oxana, Tiunova, Anya, Born, Timothy L, Usman, Natalia, Staroverov, Dmitry, Lukyanov, Sergey, Panchin, Yury

“…We have cloned the genes PANX1, PANX2 and PANX3, encoding putative gap junction proteins homologous to invertebrate innexins, which constitute a new family of…”
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c-Myc cooperates with activated Ras to induce the cdc2 promoter by Born, T L, Frost, J A, Schönthal, A, Prendergast, G C, Feramisco, J R

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cloning of a Novel Receptor Subunit, AcPL, Required for Interleukin-18 Signaling by Born, Teresa L., Thomassen, Elisabeth, Bird, Timothy A., Sims, John E.

“…We have identified a novel member of the interleukin-1 (IL-1) receptor family, which we have termed AcPL. In transient transfection assays, we were unable to…”
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Microinjection of anti-p21 antibodies induces senescent Hs68 human fibroblasts to synthesize DNA but not to divide by YULIANG MA, PRIGENT, S. A, BORN, T. L, MONELL, C. R, FERAMISCO, J. R, BERTOLAET, B. L

“…Replicative senescence is characterized by irreversible growth arrest and has been defined by four genetic complementation groups. One of these groups is…”
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A Poxvirus Protein That Binds to and Inactivates IL-18, and Inhibits NK Cell Response by Born, Teresa L, Morrison, Lynda A, Esteban, David J, VandenBos, Tim, Thebeau, Lydia G, Chen, Nanhai, Spriggs, Melanie K, Sims, John E, Buller, R. Mark L

“…IL-18 induces IFN-gamma and NK cell cytotoxicity, making it a logical target for viral antagonism of host defense. We demonstrate that the ectromelia poxvirus…”
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Identification and characterization of two members of a novel class of the interleukin-1 receptor (IL-1R) family. Delineation of a new class of IL-1R-related proteins based on signaling by Born, T L, Smith, D E, Garka, K E, Renshaw, B R, Bertles, J S, Sims, J E

“…Two novel members of the interleukin-1 receptor (IL-1R) family, identified by homology searches of human genomic sequence data bases, are described. The genes…”
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Structure/function studies on enzymes in the diaminopimelate pathway of bacterial cell wall biosynthesis by Born, Timothy L, Blanchard, John S

“…Within the past 18 months work has continued on the structure and mechanisms of enzymes involved in the diaminopimelic acid/lysine biosynthetic pathway. A…”
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Elevated cyclins and cyclin-dependent kinase activity in the rhabdomyosarcoma cell line RD by KNUDSEN, E. S, PAZZAGLI, C, BORN, T. L, BERTOLAET, B. L, KNUDSEN, K. E, ARDEN, K. C, HENRY, R. R, FERAMISCO, J. R

“…An important early event in the differentiation of skeletal muscle cells is exit from the cell cycle, after which full expression of the muscle phenotype…”
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Enzyme-Catalyzed Acylation of Homoserine:  Mechanistic Characterization of the Escherichia coli metA-Encoded Homoserine Transsuccinylase by Born, Timothy L, Blanchard, John S

“…The first unique step in bacterial and plant methionine biosynthesis involves the activation of the γ-hydroxyl of homoserine. In Escherichia coli, this…”
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Enzyme-Catalyzed Acylation of Homoserine:  Mechanistic Characterization of the Haemophilus influenzae met2-Encoded Homoserine Transacetylase by Born, Timothy L, Franklin, Matthew, Blanchard, John S

“…The first unique step in bacterial and plant methionine biosynthesis involves the acylation of the γ-hydroxyl of homoserine. In Haemophilus influenzae,…”
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Hydrolysis of N-Succinyl-l,l-diaminopimelic Acid by the Haemophilus influenzae dapE-Encoded Desuccinylase:  Metal Activation, Solvent Isotope Effects, and Kinetic Mechanism by Born, Timothy L, Zheng, Renjian, Blanchard, John S

“…Hydrolysis of N-succinyl-l,l-diaminopimelic acid by the dapE-encoded desuccinylase is required for the bacterial synthesis of lysine and meso-diaminopimelic…”
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Stained colonies facilitate alignment in a nonradioactive colony hybridization by Born, T L, Miyada, C G

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A DNA sequence for the discrimination of Neisseria gonorrhoeae from other Neisseria species by Miyada, C G, Born, T L

“…A 350 base pair Neisseria gonorrhoeae DNA restriction fragment was cloned after subtractive hybridization to Neisseria meningitidis DNA. This restriction…”
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Inhibition of calcineurin by cyclosporin A-cyclophilin requires calcineurin B by Haddy, Alice, Swanson, Selene K.-H., Born, Timothy L., Rusnak, Frank

“…The interaction of the immunosuppressive complex cyclosporin A-cyclophilin (CsA-CyP) with the Ca 2+/calmodulin-dependent protein phosphatase calcineurin is…”
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4-(Fluoromethyl)phenyl Phosphate Acts as a Mechanism-based Inhibitor of Calcineurin (∗) by Born, Timothy L., Myers, Jason K., Widlanski, Theodore S., Rusnak, Frank

“…The compound 4-(fluoromethyl)phenyl phosphate (FMPP), recently shown to be a mechanism-based inhibitor of prostatic acid phosphatase (Myers, J. K., and…”
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Positive Regulation of cdc2 Gene Activity by Protein Phosphatase Type 2A by Jaramillo-Babb, V L, Sugarmans, J L, Scavetta, R, Wang, S J, Berndt, N, Born, T L, Glass, C K, Schönthal, A H

“…Several lines of evidence indicate that serine/threonine protein phosphatases may act as negative regulators of cellular growth. For example, treatment of…”
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Substrate analysis of homoserine acyltransferase from Bacillus cereus by Ziegler, Katharine, Yusupov, Muzaffar, Bishop, Barney, Born, Timothy L.

“…Substrate specificity within the family of enzymes designated as homoserine transsuccinylases is variable, with some organisms utilizing succinyl-CoA and other…”
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Identification of Catalytic Cysteine, Histidine, and Lysine Residues in Escherichia coli Homoserine Transsuccinylase by Ziegler, Katharine, Noble, Schroeder M, Mutumanje, Elissa, Bishop, Barney, Huddler, Donald P, Born, Timothy L

“…Homoserine transsuccinylase catalyzes the succinylation of homoserine in several bacterial species, the first unique step in methionine biosynthesis in these…”
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A genomic and proteomic study of the spectrum of nonalcoholic fatty liver disease by YOUNOSSI, Zobair M, BARANOVA, Ancha, ONG, Janus P, GOODMAN, Zachary, CHANDHOKE, Vikas, ZIEGLER, Katharine, DEL GIACCO, Luca, SCHLAUCH, Karen, BORN, Timothy L, ELARINY, Hazem, GORRETA, Francesco, VANMETER, Amy, YOUNOSZAI, Abraham

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and some of its forms are progressive. This study describes the profiling of…”
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