Search Results - "BORK, P"

Interactive Tree Of Life v2: online annotation and display of phylogenetic trees made easy by Letunic, Ivica, Bork, Peer

“…Interactive Tree Of Life (http://itol.embl.de) is a web-based tool for the display, manipulation and annotation of phylogenetic trees. It is freely available…”
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Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson's disease patients by Bedarf, J R, Hildebrand, F, Coelho, L P, Sunagawa, S, Bahram, M, Goeser, F, Bork, P, Wüllner, U

“…Parkinson's disease (PD) presently is conceptualized as a protein aggregation disease in which pathology involves both the enteric and the central nervous…”
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Tara Oceans studies plankton at PLANETARY SCALE by Bork, P., Bowler, C., de Vargas, C., Gorsky, G., Karsenti, E., Wincker, P.

“…The ocean is the largest ecosystem on Earth, and yet we know very little about it. This is particularly true for the plankton that inhabit the ocean. Although…”
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STRING database in 2011: functional interaction networks of proteins, globally integrated and scored by Szklarczyk, Damian, Franceschini, Andrea, Kuhn, Michael, Simonovic, Milan, Roth, Alexander, Minguez, Pablo, Doerks, Tobias, Stark, Manuel, Muller, Jean, Bork, Peer, Jensen, Lars J, Mering, Christian von

“…An essential prerequisite for any systems-level understanding of cellular functions is to correctly uncover and annotate all functional interactions among…”
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50 The Rise of Bioinformatics in Data-driven Cancer Research by Bork, P

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eggNOG v3.0: orthologous groups covering 1133 organisms at 41 different taxonomic ranges by Powell, Sean, Szklarczyk, Damian, Trachana, Kalliopi, Roth, Alexander, Kuhn, Michael, Muller, Jean, Arnold, Roland, Rattei, Thomas, Letunic, Ivica, Doerks, Tobias, Jensen, Lars J., von Mering, Christian, Bork, Peer

“…Orthologous relationships form the basis of most comparative genomic and metagenomic studies and are essential for proper phylogenetic and functional analyses…”
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SMART 7: recent updates to the protein domain annotation resource by Letunic, I., Doerks, T., Bork, P.

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STITCH: interaction networks of chemicals and proteins by Kuhn, Michael, von Mering, Christian, Campillos, Monica, Jensen, Lars Juhl, Bork, Peer

“…The knowledge about interactions between proteins and small molecules is essential for the understanding of molecular and cellular functions. However,…”
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Quantitative Phylogenetic Assessment of Microbial Communities in Diverse Environments by von Mering, C, Hugenholtz, P, Raes, J, Tringe, S.G, Doerks, T, Jensen, L.J, Ward, N, Bork, P

“…The taxonomic composition of environmental communities is an important indicator of their ecology and function. We used a set of protein-coding marker genes,…”
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eggNOG: automated construction and annotation of orthologous groups of genes by Jensen, Lars Juhl, Julien, Philippe, Kuhn, Michael, von Mering, Christian, Muller, Jean, Doerks, Tobias, Bork, Peer

“…The identification of orthologous genes forms the basis for most comparative genomics studies. Existing approaches either lack functional annotation of the…”
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The gut microbiome is associated with behavioural task in honey bees by Jones, J. C., Fruciano, C., Marchant, J., Hildebrand, F., Forslund, S., Bork, P., Engel, P., Hughes, W. O. H.

“…The gut microbiome is recognised as playing an integral role in the health and ecology of a wide variety of animal taxa. However, the relationship between…”
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Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses by Kunath, B J, Hickl, O, Queirós, P, Martin-Gallausiaux, C, Lebrun, L A, Halder, R, Laczny, C C, Schmidt, T S B, Hayward, M R, Becher, D, Heintz-Buschart, A, de Beaufort, C, Bork, P, May, P, Wilmes, P

“…Alterations to the gut microbiome have been linked to multiple chronic diseases. However, the drivers of such changes remain largely unknown. The oral cavity…”
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eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations by Muller, J, Szklarczyk, D, Julien, P, Letunic, I, Roth, A, Kuhn, M, Powell, S, von Mering, C, Doerks, T, Jensen, L.J, Bork, P

“…The identification of orthologous relationships forms the basis for most comparative genomics studies. Here, we present the second version of the eggNOG…”
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NetworKIN: a resource for exploring cellular phosphorylation networks by Linding, Rune, Jensen, Lars Juhl, Pasculescu, Adrian, Olhovsky, Marina, Colwill, Karen, Bork, Peer, Yaffe, Michael B, Pawson, Tony

“…Protein kinases control cellular responses by phosphorylating specific substrates. Recent proteome-wide mapping of protein phosphorylation sites by mass…”
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STRING: a web-server to retrieve and display the repeatedly occurring neighbourhood of a gene by Snel, B, Lehmann, G, Bork, P, Huynen, M A

“…The repeated occurrence of genes in each other's neighbourhood on genomes has been shown to indicate a functional association between the proteins they encode…”
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Corrosion and corrosion fatigue of AISI 420C (X46Cr13) at 60°C in CO2-saturated artificial geothermal brine by Pfennig, A., Wiegand, R., Wolf, M., Bork, C.-P.

“…► All-purpose corrosion chamber: ⩽100°C, 1bar, flowing liquid media, gas mixtures. ► Corrosion and corrosion fatigue: AISI 420C (S–N curve, kinetic analysis at…”
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The gut microbiome in Parkinson's disease by Bedarf, J R, Hildebrand, F, Goeser, F, Bork, P, Wüllner, U

“…The vast majority of Parkinson's disease (PD) cases are of sporadic origin and despite extensive research in recent years, the etiology still remains unclear…”
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Charting the Proteomes of Organisms with Unsequenced Genomes by MALDI-Quadrupole Time-of-Flight Mass Spectrometry and BLAST Homology Searching by Shevchenko, Andrej, Sunyaev, Shamil, Loboda, Alexander, Shevchenko, Anna, Bork, Peer, Ens, Werner, Standing, Kenneth G

“…MALDI-quadrupole time-of-flight mass spectrometry was applied to identify proteins from organisms whose genomes are still unknown. The identification was…”
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Computational characterization of multiple Gag-like human proteins by Campillos, Mónica, Doerks, Tobias, Shah, Parantu K., Bork, Peer

“…In a genome-wide analysis, we have identified 85 human genes encoding 103 protein isoforms that resemble retroviral Gag proteins. These genes were domesticated…”
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Failures of Berlin Freedom Bell since 1966 by Bettge, D., Bork, C.-P.

“…•In 1950 the 10tons “Freedom Bell” was donated to the city of West Berlin.•In 1966 the clapper hanger and in 1979 the clapper broke down.•Fatigue failures of…”
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