Search Results - "BORDONI, Veronica"
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Immunogenicity to COVID-19 mRNA vaccine third dose in people living with HIV
Published in Nature communications (22-08-2022)“…In order to investigate safety and immunogenicity of SARS-CoV-2 vaccine third dose in people living with HIV (PLWH), we analyze anti-RBD, microneutralization…”
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Emerging viral infections in immunocompromised patients: A great challenge to better define the role of immune response
Published in Frontiers in immunology (09-03-2023)“…The immune response to invading pathogens is characterized by the rapid establishment of a complex network of cellular interactions and soluble signals. The…”
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The unbalanced p53/SIRT1 axis may impact lymphocyte homeostasis in COVID-19 patients
Published in International journal of infectious diseases (01-04-2021)“…•Significant reduction of SIRT1 in COVID-19 patients may play a role in the maintenance of p53 in the active form.•Significant increase of p21 in COVID-19…”
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Myeloid-Derived Suppressor Cells in COVID-19: The Paradox of Good
Published in Frontiers in immunology (27-04-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Viral…”
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Persistent Spike-specific T cell immunity despite antibody reduction after 3 months from SARS-CoV-2 BNT162b2-mRNA vaccine
Published in Scientific reports (23-04-2022)“…Vaccine is the main public health measure to reduce SARS-CoV-2 transmission and hospitalization, and a massive scientific effort worldwide resulted in the…”
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Myeloid-Derived Suppressor Cells Specifically Suppress IFN-γ Production and Antitumor Cytotoxic Activity of Vδ2 T Cells
Published in Frontiers in immunology (06-06-2018)“…γδ T cells represent less than 5% of circulating T cells; they exert a potent cytotoxic function against tumor or infected cells and secrete cytokines like…”
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Restoration of WT1/miR-769-5p axis by HDAC1 inhibition promotes MMT reversal in mesenchymal-like mesothelial cells
Published in Cell death & disease (17-11-2022)“…Histone acetylation/deacetylation play an essential role in modifying chromatin structure and in regulating cell plasticity in eukaryotic cells. Therefore,…”
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A new procedure to analyze polymorphonuclear myeloid derived suppressor cells in cryopreserved samples cells by flow cytometry
Published in PloS one (30-08-2018)“…Myeloid derived suppressor cells (MDSC) is a heterogeneous subset of immature and mature cells of the myeloid lineage, undergoing expansion during pathologic…”
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Multi-omics approach to COVID-19: a domain-based literature review
Published in Journal of translational medicine (07-12-2021)“…Omics data, driven by rapid advances in laboratory techniques, have been generated very quickly during the COVID-19 pandemic. Our aim is to use omics data to…”
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10
HDAC1 inhibition by MS-275 in mesothelial cells limits cellular invasion and promotes MMT reversal
Published in Scientific reports (31-05-2018)“…Peritoneal fibrosis is a pathological alteration of the peritoneal membrane occurring in a variety of conditions including peritoneal dialysis (PD),…”
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Expansion of Myeloid Derived Suppressor Cells Contributes to Platelet Activation by L-Arginine Deprivation during SARS-CoV-2 Infection
Published in Cells (Basel, Switzerland) (17-08-2021)“…Massive platelet activation and thrombotic events characterize severe COVID-19, highlighting their critical role in SARS-CoV-2-induced immunopathology. Since…”
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SARS-CoV-2 Infection of Airway Epithelium Triggers Pulmonary Endothelial Cell Activation and Senescence Associated with Type I IFN Production
Published in Cells (Basel, Switzerland) (01-09-2022)“…Airway epithelial cells represent the main target of SARS-CoV-2 replication but several pieces of evidence suggest that endothelial cells (ECs), lining…”
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Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells
Published in Scientific reports (24-07-2017)“…The definition of the immunological response to Zika (ZIKV) infection in humans represents a key issue to identify protective profile useful for vaccine…”
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The BNT162b2 vaccine induces humoral and cellular immune memory to SARS-CoV-2 Wuhan strain and the Omicron variant in children 5 to 11 years of age
Published in Frontiers in immunology (15-12-2022)“…SARS-CoV-2 mRNA vaccines prevent severe COVID-19 by generating immune memory, comprising specific antibodies and memory B and T cells. Although children are at…”
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Naïve/Effector CD4 T cell ratio as a useful predictive marker of immune reconstitution in late presenter HIV patients: A multicenter study
Published in PloS one (23-12-2019)“…A significant proportion of HIV-infected patients experiencing a late diagnosis highlights the need to define immunological protocols able to help the…”
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Elevated P-Selectin in Severe Covid-19: Considerations for Therapeutic Options
Published in Mediterranean journal of hematology and infectious diseases (01-03-2021)“…Coronavirus disease 2019 (COVID-19) is mainly a respiratory tract disease and acute respiratory failure with diffuse microvascular pulmonary thrombosis are…”
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Coordinate Induction of Humoral and Spike Specific T-Cell Response in a Cohort of Italian Health Care Workers Receiving BNT162b2 mRNA Vaccine
Published in Microorganisms (Basel) (16-06-2021)“…Vaccination is the main public health measure to reduce SARS-CoV-2 transmission and hospitalization, and a massive worldwide scientific effort resulted in the…”
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PMN-MDSC Frequency Discriminates Active Versus Latent Tuberculosis and Could Play a Role in Counteracting the Immune-Mediated Lung Damage in Active Disease
Published in Frontiers in immunology (26-04-2021)“…Tuberculosis (TB), due to infection, is still the principal cause of death caused by a single infectious agent. The balance between the bacillus and host…”
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IL-18 and Stem Cell Factor affect hematopoietic progenitor cells in HIV-infected patients treated during primary HIV infection
Published in Cytokine (Philadelphia, Pa.) (01-03-2018)“…[Display omitted] •ART in primary HIV infection restores the decline of lymphoid progenitors.•ART in primary HIV infection induces a decrease of IL-18 and an…”
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Functional CVIDs phenotype clusters identified by the integration of immune parameters after BNT162b2 boosters
Published in Frontiers in immunology (25-05-2023)“…Assessing the response to vaccinations is one of the diagnostic criteria for Common Variable Immune Deficiencies (CVIDs). Vaccination against SARS-CoV-2…”
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