Search Results - "BOPPART, MARNI D."

Integrin signaling: linking mechanical stimulation to skeletal muscle hypertrophy by Boppart, Marni D, Mahmassani, Ziad S

“…The α β -integrin is a transmembrane adhesion protein that connects laminin in the extracellular matrix (ECM) with actin in skeletal muscle fibers. The α β…”
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Influence of exercise and aging on extracellular matrix composition in the skeletal muscle stem cell niche by Garg, Koyal, Boppart, Marni D

“…Skeletal muscle is endowed with a remarkable capacity for regeneration, primarily due to the reserve pool of muscle resident satellite cells. The satellite…”
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Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions by Roberts, Michael D, McCarthy, John J, Hornberger, Troy A, Phillips, Stuart M, Mackey, Abigail L, Nader, Gustavo A, Boppart, Marni D, Kavazis, Andreas N, Reidy, Paul T, Ogasawara, Riki, Libardi, Cleiton A, Ugrinowitsch, Carlos, Booth, Frank W, Esser, Karyn A

“…Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have been extensively researched since the landmark report by Morpurgo (1897) of…”
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The Impact of Exercise on Statin-Associated Skeletal Muscle Myopathy by Chung, Hae R, Vakil, Mayand, Munroe, Michael, Parikh, Alay, Meador, Benjamin M, Wu, Pei T, Jeong, Jin H, Woods, Jeffrey A, Wilund, Kenneth R, Boppart, Marni D

“…HMG-CoA reductase inhibitors (statins) are the most effective pharmacological means of reducing cardiovascular disease risk. The most common side effect of…”
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Eccentric exercise facilitates mesenchymal stem cell appearance in skeletal muscle by Valero, M Carmen, Huntsman, Heather D, Liu, Jianming, Zou, Kai, Boppart, Marni D

“…Eccentric, or lengthening, contractions result in injury and subsequently stimulate the activation and proliferation of satellite stem cells which are…”
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mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms by Ge, Yejing, Wu, Ai-Luen, Warnes, Christine, Liu, Jianming, Zhang, Chongben, Kawasome, Hideki, Terada, Naohiro, Boppart, Marni D, Schoenherr, Christopher J, Chen, Jie

“…Rapamycin-sensitive signaling is required for skeletal muscle differentiation and remodeling. In cultured myoblasts, the mammalian target of rapamycin (mTOR)…”
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The effects of high fat diet and moderate exercise on TGFβ1 and collagen deposition in mouse skeletal muscle by Pincu, Yair, Linden, Melissa A., Zou, Kai, Baynard, Tracy, Boppart, Marni D.

“…•High fat diet increased F4/80 and IL-6 gene expression in skeletal muscle.•Exercise suppressed the elevation of F4/80 and IL-6 mRNA with high fat diet.•High…”
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The α7β1-integrin increases muscle hypertrophy following multiple bouts of eccentric exercise by KAI ZOU, MEADOR, Benjamin M, JOHNSON, Brian, HUNTSMAN, Heather D, MAHMASSANI, Ziad, CARMEN VALERO, M, HUEY, Kimberly A, BOPPART, Marni D

“…Mechanical stimuli increase skeletal muscle growth in a mammalian target of rapamycin (mTOR)- and p70(S6K)-dependent manner. It has been proposed that…”
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Matrix Topography Regulates Synaptic Transmission at the Neuromuscular Junction by Ko, Eunkyung, Yu, Seung Jung, Pagan‐Diaz, Gelson J., Mahmassani, Ziad, Boppart, Marni D., Im, Sung Gap, Bashir, Rashid, Kong, Hyunjoon

“…Recreation of a muscle that can be controlled by the nervous system would provide a major breakthrough for treatments of injury and diseases. However, the…”
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Defining a role for non-satellite stem cells in the regulation of muscle repair following exercise by Boppart, Marni D, De Lisio, Michael, Zou, Kai, Huntsman, Heather D

“…Skeletal muscle repair is essential for effective remodeling, tissue maintenance, and initiation of beneficial adaptations post-eccentric exercise. A series of…”
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β1D chain increases α7β1 integrin and laminin and protects against sarcolemmal damage in mdx mice by Liu, Jianming, Milner, Derek J., Boppart, Marni D., Ross, Robert S., Kaufman, Stephen J.

“…The dystrophin-glycoprotein complex connects myofibers with extracellular matrix laminin. In Duchenne muscular dystrophy, this linkage system is absent and the…”
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The α7β1-integrin accelerates fiber hypertrophy and myogenesis following a single bout of eccentric exercise by Lueders, Tara N, Zou, Kai, Huntsman, Heather D, Meador, Benjamin, Mahmassani, Ziad, Abel, Megan, Valero, M Carmen, Huey, Kimberly A, Boppart, Marni D

“…The α(7)β(1)-integrin is a heterodimeric transmembrane protein that adheres to laminin in the extracellular matrix, representing a critical link that maintains…”
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Diet-induced obesity regulates adipose-resident stromal cell quantity and extracellular matrix gene expression by Pincu, Yair, Huntsman, Heather D., Zou, Kai, De Lisio, Michael, Mahmassani, Ziad S., Munroe, Michael R., Garg, Koyal, Jensen, Tor, Boppart, Marni D.

“…Adipose tissue expansion during periods of excess nutrient intake requires significant turnover of the extracellular matrix (ECM) to allow for maximal lipid…”
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Laminin‐111 Improves Skeletal Muscle Stem Cell Quantity and Function Following Eccentric Exercise by Zou, Kai, De Lisio, Michael, Huntsman, Heather D., Pincu, Yair, Mahmassani, Ziad, Miller, Matthew, Olatunbosun, Dami, Jensen, Tor, Boppart, Marni D.

“…The study's purpose was to determine the extent to which laminin‐111 (LM‐111) can alter stem cell quantity following eccentric exercise‐induced damage in mice…”
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In vivo multimodal microscopy for detecting bone-marrow-derived cell contribution to skin regeneration by Graf, Benedikt W., Bower, Andrew J., Chaney, Eric J., Marjanovic, Marina, Adie, Steven G., De Lisio, Michael, Valero, Maria C., Boppart, Marni D., Boppart, Stephen A.

“…Bone‐marrow (BM)‐derived cells have been shown to be capable of aiding skin regeneration in vivo by differentiating into keratinocytes. However, the conditions…”
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Optimization of a pericyte therapy to improve muscle recovery after limb immobilization by Wu, Yu-Fu, Lapp, Samuel, Dvoretskiy, Svyatoslav, Garcia, Gabriela, Kim, Michael, Tannehill, Amanda, Daniels, Laureen, Boppart, Marni D

“…Extended bed rest or limb immobilization can significantly reduce skeletal muscle mass and function. Recovery may be incomplete, particularly in older adults…”
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Pericyte transplantation improves skeletal muscle recovery following hindlimb immobilization by Munroe, Michael, Dvoretskiy, Svyatoslav, Lopez, Amber, Leong, Jiayu, Dyle, Michael C., Kong, Hyunjoon, Adams, Christopher M., Boppart, Marni D.

“…ABSTRACT Conditions of extended bed rest and limb immobilization can initiate rapid and significant loss of skeletal muscle mass and function. Physical…”
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Increases in Integrin–ILK–RICTOR–Akt Proteins, Muscle Mass, and Strength after Eccentric Cycling Training by MAVROPALIAS, GEORGIOS, WU, YU-FU, BOPPART, MARNI D., BLAZEVICH, ANTHONY J., NOSAKA, KAZUNORI

“…Recently, it has been suggested that a cellular pathway composed of integrin, integrin-linked kinase (ILK), rapamycin-insensitive companion of mTOR (RICTOR),…”
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Development of a cell-free strategy to recover aged skeletal muscle after disuse by Wu, Yu-Fu, De La Toba, Eduardo A, Dvoretskiy, Svyatoslav, Jung, Rebecca, Kim, Noah, Daniels, Laureen, Romanova, Elena V, Drnevich, Jenny, Sweedler, Jonathan V, Boppart, Marni D

“…Extended periods of bed rest and limb immobilization are required for healing post-injury or disease, yet disuse can result in significant muscle atrophy and…”
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27-Hydroxycholesterol Enhances Secretion of Extracellular Vesicles by ROS-Induced Dysregulation of Lysosomes by Das Gupta, Anasuya, Park, Jaena, Sorrells, Janet E, Kim, Hannah, Krawczynska, Natalia, Pradeep, Dhanya, Wang, Yu, Vidana Gamage, Hashni Epa, Nelczyk, Adam T, Boppart, Stephen A, Boppart, Marni D, Nelson, Erik R

“…Abstract Extracellular vesicles (EVs) serve as crucial mediators of cell-to-cell communication in normal physiology as well as in diseased states; they have…”
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