Search Results - "BOPARAI, Ravneet K"
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Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice
Published in Cell metabolism (05-03-2013)“…The evolutionarily conserved target of rapamycin (TOR) signaling controls growth, metabolism, and aging. In the first robust demonstration of…”
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Capsaicin induces "brite" phenotype in differentiating 3T3-L1 preadipocytes
Published in PloS one (29-07-2014)“…Targeting the energy storing white adipose tissue (WAT) by pharmacological and dietary means in order to promote its conversion to energy expending "brite"…”
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Capsaicin-induced transcriptional changes in hypothalamus and alterations in gut microbial count in high fat diet fed mice
Published in The Journal of nutritional biochemistry (01-09-2014)“…Obesity is a global health problem and recently it has been seen as a growing concern for developing countries. Several bioactive dietary molecules have been…”
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Finger millet bran supplementation alleviates obesity-induced oxidative stress, inflammation and gut microbial derangements in high-fat diet-fed mice
Published in British journal of nutrition (14-11-2014)“…Several epidemiological studies have shown that the consumption of finger millet (FM) alleviates diabetes-related complications. In the present study, the…”
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Involvement of Glucagon in Preventive Effect of Menthol Against High Fat Diet Induced Obesity in Mice
Published in Frontiers in pharmacology (16-11-2018)“…Glucagon mediated mechanisms have been shown to play clinically significant role in energy expenditure. The present study was designed to understand whether…”
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Expression of multiple Transient Receptor Potential channel genes in murine 3T3-L1 cell lines and adipose tissue
Published in Pharmacological reports (01-05-2013)“…Calcium and its signaling have a role in adipogenesis. Transient Receptor Potential (TRP) channels are non-selective cation channels with a high permeability…”
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Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone
Published in Cell cycle (Georgetown, Tex.) (01-04-2013)“…Growth hormone (GH) overexpression throughout life in transgenic mice is associated with the development of liver tumors at old ages. The preneoplastic…”
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Microarray based gene expression analysis of murine brown and subcutaneous adipose tissue: significance with human
Published in PloS one (26-05-2015)“…Two types of adipose tissues, white (WAT) and brown (BAT) are found in mammals. Increasingly novel strategies are being proposed for the treatment of obesity…”
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Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice
Published in International Journal of Endocrinology (01-01-2015)“…Fibroblast growth factor 21 (FGF21) modulates a diverse range of biological functions, including glucose and lipid metabolism, adaptive starvation response,…”
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Cinnamaldehyde supplementation prevents fasting-induced hyperphagia, lipid accumulation, and inflammation in high-fat diet-fed mice
Published in BioFactors (Oxford) (01-03-2016)“…Cinnamaldehyde, a bioactive component of cinnamon, is increasingly gaining interest for its preventive and therapeutic effects against metabolic complications…”
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Functional food ingredients for the management of obesity and associated co-morbidities – A review
Published in Journal of functional foods (01-07-2013)“…Worldwide obesity has reached a pandemic proportion. World Health Organization (WHO) estimates that by 2020, two thirds of the global disease burden will be…”
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Allicin, a dietary trpa1 agonist, prevents high fat diet-induced dysregulation of gut hormones and associated complications
Published in Food & function (15-11-2021)“…Given the global epidemic of diabesity (co-existence of both diabetes and obesity), novel approaches that target gut hormone secretion and their modulation may…”
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Kodo millet whole grain and bran supplementation prevents high-fat diet induced derangements in a lipid profile, inflammatory status and gut bacteria in mice
Published in Food & function (01-03-2017)“…The protective role of kodo millet whole grain and bran supplementation in diet induced obesity has not been investigated. Here we have studied the role of…”
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Specific suppression of insulin sensitivity in growth hormone receptor gene‐disrupted (GHR‐KO) mice attenuates phenotypic features of slow aging
Published in Aging cell (01-12-2014)“…Summary In addition to their extended lifespans, slow‐aging growth hormone receptor/binding protein gene‐disrupted (knockout) (GHR‐KO) mice are hypoinsulinemic…”
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Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis
Published in Biological chemistry (01-10-2010)“…In contrast to its stimulatory effects on musculature, bone, and organ development, and its lipolytic effects, growth hormone (GH) opposes insulin effects on…”
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Preservation of blood glucose homeostasis in slow-senescing somatotrophism-deficient mice subjected to intermittent fasting begun at middle or old age
Published in AGE (01-06-2014)“…Poor blood glucose homeostatic regulation is common, consequential, and costly for older and elderly populations, resulting in pleiotrophically adverse…”
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Female PAPP-A knockout mice are resistant to metabolic dysfunction induced by high-fat/high-sucrose feeding at middle age
Published in AGE (01-06-2015)“…Longevity and aging are influenced by common intracellular signals of the insulin/insulin-like growth factor (IGF)-1 pathway. Abnormally high levels of…”
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GH/STAT5 signaling during the growth period in livers of mice overexpressing GH
Published in Journal of molecular endocrinology (01-04-2015)“…GH/STAT5 signaling is desensitized in the liver in adult transgenic mice overexpressing GH; however, these animals present greater body size. To assess whether…”
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Implications of oxidative stress in high sucrose low magnesium diet fed rats
Published in European journal of nutrition (01-10-2007)“…Background Magnesium deficiency as well as excess sucrose in the diet have been shown to be associated with the generation of reactive oxygen species (ROS)…”
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