Search Results - "BONSE, Susanne"
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Ajoene Is an Inhibitor and Subversive Substrate of Human Glutathione Reductase and Trypanosoma cruzi Trypanothione Reductase: Crystallographic, Kinetic, and Spectroscopic Studies
Published in Journal of medicinal chemistry (11-02-1999)“…Ajoene ((E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide), a garlic-derived natural compound, is a covalent inhibitor as well as a substrate of human…”
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Journal Article -
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(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes Are Irreversible Inhibitors of Trypanosoma cruzi Trypanothione Reductase But Not of Human Glutathione Reductase
Published in Journal of medicinal chemistry (14-12-2000)“…(2,2':6',2"-terpyridine)platinum(II) complexes possess pronounced cytostatic activities against trypanosomes and leishmania. As shown here, the complexes are…”
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Inhibition of Trypanosoma cruzi Trypanothione Reductase by Acridines: Kinetic Studies and Structure−Activity Relationships
Published in Journal of medicinal chemistry (30-12-1999)“…Series of 9-amino and 9-thioacridines have been synthesized and studied as inhibitors of trypanothione reductase (TR) from Trypanosoma cruzi, the causative…”
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(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes Are Irreversible Inhibitors of Trypanosoma c ruzi Trypanothione Reductase But Not of Human Glutathione Reductase
Published in Journal of medicinal chemistry (14-12-2000)“…(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) complexes possess pronounced cytostatic activities against trypanosomes and leishmania. As shown here, the complexes are…”
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Journal Article -
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