Search Results - "BONNER, Robert F"
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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
Published in Nature cell biology (01-07-2003)“…Histone H2AX is rapidly phosphorylated in the chromatin micro-environment surrounding a DNA double-strand break (DSB). Although H2AX deficiency is not…”
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Modeling Photo-Bleaching Kinetics to Create High Resolution Maps of Rod Rhodopsin in the Human Retina
Published in PloS one (21-07-2015)“…We introduce and describe a novel non-invasive in-vivo method for mapping local rod rhodopsin distribution in the human retina over a 30-degree field. Our…”
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3
Post-analysis follow-up and validation of microarray experiments
Published in Nature genetics (01-12-2002)“…Measurement of gene-expression profiles using microarray technology is becoming increasingly popular among the biomedical research community. Although there…”
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Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2009)“…The gene networks underlying closure of the optic fissure during vertebrate eye development are poorly understood. Here, we profile global gene expression…”
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Laser Capture Microdissection
Published in Science (American Association for the Advancement of Science) (08-11-1996)“…Laser capture microdissection (LCM) under direct microscopic visualization permits rapid one-step procurement of selected human cell populations from a section…”
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Laser-capture microdissection: opening the microscopic frontier to molecular analysis
Published in Trends in genetics (01-07-1998)“…As the list of expressed human genes expands, a major scientific challenge is to understand the molecular events that drive normal tissue morphogenesis and the…”
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Histological staining methods preparatory to laser capture microdissection significantly affect the integrity of the cellular RNA
Published in BMC genomics (27-04-2006)“…Gene expression profiling by microarray analysis of cells enriched by laser capture microdissection (LCM) faces several technical challenges. Frozen sections…”
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8
RedundancyMiner: De-replication of redundant GO categories in microarray and proteomics analysis
Published in BMC bioinformatics (10-02-2011)“…The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization…”
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Selective Gene Expression in Magnocellular Neurons in Rat Supraoptic Nucleus
Published in The Journal of neuroscience (11-08-2004)“…Oxytocin- and vasopressin-producing magnocellular neurons (MCNs) of the hypothalamo-neurohypophysial system are the only neuronal phenotypes present in the rat…”
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10
Fundus Autofluorescence in Type 2 Idiopathic Macular Telangiectasia: Correlation with Optical Coherence Tomography and Microperimetry
Published in American journal of ophthalmology (01-10-2009)“…Purpose To use multiple imaging methods to investigate patients with type 2 idiopathic macular telangiectasia (IMT) at different disease severity stages so as…”
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Assessment of Gene Expression in Head and Neck Carcinoma Using Laser Capture Microdissection and Real-Time Reverse Transcription Polymerase Chain Reaction
Published in The Laryngoscope (01-12-2004)“…Objectives: To quantify gene expression in tumor cells from human head and neck squamous cell carcinomas (HNSCC) using laser capture microdissection (LCM)…”
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Journal Article Conference Proceeding -
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Expression profiling during ocular development identifies 2 NIz genes with a critical role in optic fissure closure
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2009)“…The gene networks underlying closure of the optic fissure during vertebrate eye development are poorly understood. Here, we profile global gene expression…”
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Journal Article -
13
Laser Capture Microdissection: Molecular Analysis of Tissue
Published in Science (American Association for the Advancement of Science) (21-11-1997)“…The integrity of genetic testing methods is often compromised by contamination of input DNA or RNA. Laser capture microdissection is an effective method of…”
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Expression microdissection adapted to commercial laser dissection instruments
Published in Nature protocols (01-04-2011)“…Laser-based microdissection facilitates the isolation of specific cell populations from clinical or animal model tissue specimens for molecular analysis…”
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A model of spectral filtering to reduce photochemical damage in age-related macular degeneration
Published in Transactions of the American Ophthalmological Society (2004)“…Cumulative sunlight exposure and cataract surgery are reported risk factors for advanced age-related macular degeneration (AMD). Laboratory studies suggest…”
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Nonlinear gene cluster analysis with labeling for microarray gene expression data in organ development
Published in BMC proceedings (28-05-2011)“…The gene networks underlying closure of the optic fissure during vertebrate eye development are not well-understood. We use a novel clustering method based on…”
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17
Immunoguided microdissection techniques
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2011)“…Over the past 15 years, laser-based microdissection has improved the precision by which scientists can procure cells of interest from a heterogeneous tissue…”
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Journal Article -
18
Visible-light photon migration through myocardium in vivo
Published in The American journal of physiology (01-08-1999)“…Empirical data between 510 and 590 nm of diffuse reflected light from the pig heart in vivo have shown that myoglobin and cytochrome c absorption peaks with…”
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Journal Article -
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Assessment of the correlation of platelet morphology with in vivo recovery and survival
Published in Transfusion (Philadelphia, Pa.) (01-08-2005)“…BACKGROUND: There is continuing interest in the development of in vitro tests evaluating the in vivo function, recovery, and survival of platelets stored for…”
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A Preservation Method That Allows Recovery of Intact RNA from Tissues Dissected by Laser Capture Microdissection
Published in Analytical biochemistry (15-01-2002)“…We report a novel method for preparing samples for laser capture microdissection. The procedure described here permits extraction of intact RNA while…”
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