Search Results - "BONILLA, Leo E"
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Absolute Quantification of the G Protein-Coupled Receptor Rhodopsin by LC/MS/MS Using Proteolysis Product Peptides and Synthetic Peptide Standards
Published in Analytical chemistry (Washington) (01-02-2003)“…Methods for the absolute quantification of a membrane protein are described using isotopically labeled or unlabeled synthetic peptides as standards. Synthetic…”
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The evolution of tools for protein phosphorylation site analysis: from discovery to clinical application
Published in BioTechniques (01-04-2008)“…The importance of the analysis of signaling pathways has been proven for many years by the elucidation of key signaling molecules. However, in most cases these…”
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24-Hour Lock Mass Protection
Published in Journal of proteome research (04-02-2011)“…The positive role and application of highly accurate mass measurements in proteomics is well documented. The new generation of hybrid FTMS and Q-TOF…”
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Maximizing the sensitivity and reliability of peptide identification in large-scale proteomic experiments by harnessing multiple search engines
Published in Proteomics (Weinheim) (01-03-2010)“…Despite recent advances in qualitative proteomics, the automatic identification of peptides with optimal sensitivity and accuracy remains a difficult goal. To…”
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Free and total biotherapeutic evaluation in chromatographic assays: interference from targets and immunogenicity
Published in Bioanalysis (01-10-2012)“…Measurement of drug concentrations is critical during drug development, supporting evaluation of safety and efficacy in the context of pharmacokinetics…”
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Intra-specific variability of feverfew: correlations between parthenolide, morphological traits and seed origin
Published in Planta medica (01-10-2000)“…Parthenolide, a biologically active sesquiterpene lactone found in feverfew [Tanacetum parthenium (L.) Schultz Bip., Asteraceae], has been indirectly linked to…”
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Quantitation of 4-Oxo-4-(3-pyridyl)butanoic Acid and Enantiomers of 4-Hydroxy-4-(3-pyridyl)butanoic Acid in Human Urine: A Substantial Pathway of Nicotine Metabolism
Published in Chemical research in toxicology (01-02-1999)“…A liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry (LC-APCI-MS/MS) method was developed to analyze human urine for…”
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Lactols in Hydrolysates of DNA Treated with α-Acetoxy-N-nitrosopyrrolidine or Crotonaldehyde
Published in Chemical research in toxicology (01-12-1998)“…α-Acetoxy-N-nitrosopyrrolidine (α-acetoxyNPYR) is a stable precursor to α-hydroxyNPYR, the initial product of metabolism and proposed proximate carcinogen of…”
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Heme from Alzheimer's brain inhibits muscarinic receptor binding via thiyl radical generation
Published in Brain research (01-08-1997)“…An endogenous inhibitor (<3500 Da) of antagonist binding to the muscarinic acetylcholine receptor (mAChR) has been reported to be elevated 3-fold in…”
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A metabolite of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in the urine of hospital workers exposed to environmental tobacco smoke
Published in Cancer epidemiology, biomarkers & prevention (01-03-1998)“…We analyzed the urine of nonsmoking hospital workers exposed to environmental tobacco smoke for…”
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