Search Results - "BONHOEFFER, S."

Developing smarter host mixtures to control plant disease by Mikaberidze, A, McDonald, B. A, Bonhoeffer, S

“…Adaptation of plant pathogens to disease control measures (both chemical and genetic) is facilitated by the genetic uniformity underlying modern…”
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Cooperation and Competition in the Evolution of ATP-Producing Pathways by Pfeiffer, Thomas, Schuster, Stefan, Bonhoeffer, Sebastian

“…Heterotrophic organisms generally face a trade-off between rate and yield of adenosine triphosphate (ATP) production. This trade-off may result in an…”
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The state of affairs in the kingdom of the Red Queen by Salathé, Marcel, Kouyos, Roger D., Bonhoeffer, Sebastian

“…One of the most prominent hypotheses to explain the ubiquity of sex and recombination is based on host–parasite interactions. Under the name of the Red Queen…”
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The competition dynamics of resistant and sensitive infections by Lee, T.E., Bonhoeffer, S., Penny, M.A.

“…Antimicrobial resistance is a major health problem with complex dynamics. Resistance may occur in an area because treated infections mutated and developed…”
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Global trends in antimicrobial resistance in animals in low- and middle-income countries by van Boeckel, T., Pires, J., Silvester, R., Zhao, C., Song, J., Criscuolo, N., Gilbert, M., Bonhoeffer, S., Laxminarayan, R.

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Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4+ and CD8+ T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection by Betts, M R, Ambrozak, D R, Douek, D C, Bonhoeffer, S, Brenchley, J M, Casazza, J P, Koup, R A, Picker, L J

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Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical applications by Pasin, Chloé, Consiglio, Camila R, Huisman, Jana S, de Lange, Ann-Marie G, Peckham, Hannah, Vallejo-Yagüe, Enriqueta, Abela, Irene A, Islander, Ulrika, Neuner-Jehle, Nadia, Pujantell, Maria, Roth, Olivia, Schirmer, Melanie, Tepekule, Burcu, Zeeb, Marius, Hachfeld, Anna, Aebi-Popp, Karoline, Kouyos, Roger D, Bonhoeffer, Sebastian

“…Although sex and gender are recognized as major determinants of health and immunity, their role is rarely considered in clinical practice and public health. We…”
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Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection by BONHOEFFER, Sebastian, REMBISZEWSKI, Michal, ORTIZ, Gabriel M, NIXON, Douglas F

“…Structured interruptions of antiretroviral therapy of HIV-1 infected individuals are currently being tested in clinical trials to study the effect…”
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Decay Kinetics of Human Immunodeficiency Virus-Specific Effector Cytotoxic T Lymphocytes after Combination Antiretroviral Therapy by Ogg, G S, Jin, X, Bonhoeffer, S, Moss, P, Nowak, M A, Monard, S, Segal, J P, Cao, Y, Rowland-Jones, S L, Hurley, A, Markowitz, M, Ho, D D, McMichael, A J, Nixon, D F

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Viral Dynamics in Hepatitis B Virus Infection by Nowak, Martin A., Bonhoeffer, Sebastian, Hill, Andrew M., Boehme, Richard, Thomas, Howard C., McDade, Hugh

“…Treatment of chronic hepatitis B virus (HBV) infections with the reverse transcriptase inhibitor lamivudine leads to a rapid decline in plasma viremia and…”
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Human immunodeficiency virus drug therapy and virus load by Bonhoeffer, S, Coffin, J M, Nowak, M A

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Viral Dynamics in vivo: Limitations on Estimates of Intracellular Delay and Virus Decay by Andreas V. M. Herz, Bonhoeffer, Sebastian, Anderson, Roy M., May, Robert M., Nowak, Martin A.

“…Anti-viral drug treatment of human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV) infections causes rapid reduction in plasma virus load…”
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Spatial Games and the Maintenance of Cooperation by Nowak, Martin A., Bonhoeffer, Sebastian, May, Robert M.

“…The Prisoner's Dilemma (PD) is a widely employed metaphor for problems associated with the evolution of cooperative behavior. We have recently proposed an…”
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Fast folding and comparison of RNA secondary structures by Hofacker, I. L., Fontana, W., Stadler, P. F., Bonhoeffer, L. S., Tacker, M., Schuster, P.

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Pre–existence and emergence of drug resistance in HIV–1 infection by Sebastian, Bonhoeffer, Martin, A. Nowak

“…Antiviral treatment of HIV–1 infection often fails because of the rapid emergence of resistant virus within weeks of the start of therapy. This raises the…”
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Mutation and the Evolution of Virulence by Bonhoeffer, Sebastian, Nowak, Martin A.

“…The evolution of parasite virulence can be influenced by intra-host mutation of the parasite and competition among different parasite mutants in the same host…”
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The Curse of the Pharaoh: The Evolution of Virulence in Pathogens with Long Living Propagules by Bonhoeffer, Sebastian, Lenski, Richard E., Ebert, Dieter

“…We used a mathematical model to evaluate the hypothesis that parasites and pathogens with long living propagules should evolve high levels of virulence, i.e…”
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Viral Quasi-Species and Recombination by Boerlijst, Maarten C., Bonhoeffer, Sebastian, Nowak, Martin A.

“…Virus populations are complex ensembles of distinct but related genomes (so called quasi-species). Mathematical descriptions of viral quasi-species focus on…”
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Intra-Host Versus Inter-Host Selection: Viral Strategies of Immune Function Impairment by Bonhoeffer, Sebastian, Nowak, Martin A.

“…We investigate the evolution of viral strategies to counteract immunological attack. These strategies can be divided into two classes: those that impair the…”
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CCTTT‐repeat polymorphism of the inducible nitric oxide synthase is not associated with HIV pathogenesis by HERSBERGER, M., BONHOEFFER, S., RAMPINI, S. K., OPRAVIL, M., MARTI‐JAUN, J., TELENTI, A., HÄNSELER, E., LEDERGERBER, B., SPECK, R. F.

“…SUMMARY Nitric oxide (NO) produced by the inducible form of nitric oxide synthase (iNOS) has bactericidal and virocidal effects. Although NO synthesis and iNOS…”
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