Search Results - "BONHAGEN, K"

Regulation and Function of T1/ST2 Expression on CD4+ T Cells: Induction of Type 2 Cytokine Production by T1/ST2 Cross-Linking by Meisel, Christian, Bonhagen, Kerstin, Lohning, Max, Coyle, Anthony J, Gutierrez-Ramos, Jose-Carlos, Radbruch, Andreas, Kamradt, Thomas

“…The orphan receptor T1/ST2, a member of the IL-1R family, is preferentially expressed on the surface of murine Th2 cells. In this study, we analyzed the…”
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Chemotactic responses of IL-4-, IL-10-, and IFN-γ-producing CD4+ T cells depend on tissue origin and microbial stimulus by Debes, G. F., Dahl, M. E., Mahiny, A. J., Bonhagen, K., Campbell, D. J., Siegmund, K., Erb, K. J., Lewis, D. B., Kamradt, T., Hamann, A.

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A pancolitis resembling human ulcerative colitis (UC) is induced by CD4+ TCR αβ T cells of athymic origin in histocompatible severe combined immunodeficient (SCID) mice by BONHAGEN, K, THOMA, S, LEITHÄUSER, F, MÖLLER, P, REIMANN, J

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Tumour necrosis factor‐alpha (TNF‐α) transcription and translation in the CD4+ T cell‐transplanted scid mouse model of colitis by WILLIAMS, A. M, WHITING, C. V, BONHAGEN, K, REIMANN, J, BREGENHOLT, S, CLAESSON, M. H, BLAND, P

“…The adoptive transfer of activated CD4+α/β T cell blasts from the spleens of immunocompetent C.B‐17+/+ or BALB/cdm2 mice into C.B‐17scid/scid (scid) mice…”
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Inducible costimulator (ICOS) blockade inhibits accumulation of polyfunctional T helper 1/T helper 17 cells and mitigates autoimmune arthritis by Frey, Oliver, Meisel, Juliane, Hutloff, Andreas, Bonhagen, Kerstin, Bruns, Lisa, Kroczek, Richard A, Morawietz, Lars, Kamradt, Thomas

“…Inducible costimulator (ICOS) and its ligand (ICOSL) regulate T and B cell responses. Glucose-6-phosphate isomerase (G6PI)-induced arthritis requires T and B…”
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Regulatory T cells control the transition from acute into chronic inflammation in glucose-6-phosphate isomerase-induced arthritis by Frey, Oliver, Reichel, Andreas, Bonhagen, Kerstin, Morawietz, Lars, Rauchhaus, Una, Kamradt, Thomas

“…Glucose-6-phosphate isomerase (G6PI)-induced arthritis is a spontaneously remitting experimental arthritis model. It was hypothesised that regulatory T cells…”
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Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10 by Löhning, Max, Hutloff, Andreas, Kallinich, Tilmann, Mages, Hans Werner, Bonhagen, Kerstin, Radbruch, Andreas, Hamelmann, Eckard, Kroczek, Richard A

“…The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did not yield information on the…”
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Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses by Kursar, Mischo, Bonhagen, Kerstin, Fensterle, Joachim, Köhler, Anne, Hurwitz, Robert, Kamradt, Thomas, Kaufmann, Stefan H E, Mittrücker, Hans-Willi

“…CD4+ T cell help is important for the generation of CD8+ T cell responses. We used depleting anti-CD4 mAb to analyze the role of CD4+ T cells for memory CD8+ T…”
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Lipopolysaccharide Injection Induces Relapses of Experimental Autoimmune Encephalomyelitis in Nontransgenic Mice via Bystander Activation of Autoreactive CD4+ Cells by Nogai, Axel, Siffrin, Volker, Bonhagen, Kerstin, Pfueller, Caspar F, Hohnstein, Thordis, Volkmer-Engert, Rudolf, Bruck, Wolfgang, Stadelmann, Christine, Kamradt, Thomas

“…Infections sometimes associate with exacerbations of autoimmune diseases through pathways that are poorly understood. Ag-specific mechanisms such as…”
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Two waves of antigen‐containing dendritic cells in vivo in experimental Leishmania major infection by Misslitz, Ana Clara, Bonhagen, Kerstin, Harbecke, Dorothee, Lippuner, Christoph, Kamradt, Thomas, Aebischer, Toni

“…Dendritic cells (DC) can induce Th1 cell differentiation by producing IL‐12. In experimental infection with Leishmania major, DC could differently respond to…”
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CC Chemokine Receptor 7 Expression by Effector/Memory CD4+ T Cells Depends on Antigen Specificity and Tissue Localization during Influenza A Virus Infection by DEBES, Gudrun F, BONHAGEN, Kerstin, WOLFF, Thorsten, KRETSCHMER, Ute, KRAUTWALD, Stefan, KAMRADT, Thomas, HAMANN, Alf

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Organ-Specific CD4+ T Cell Response During Listeria monocytogenes Infection by Kursar, Mischo, Bonhagen, Kerstin, Kohler, Anne, Kamradt, Thomas, Kaufmann, Stefan H. E, Mittrucker, Hans-Willi

“…The immune response against the intracellular bacterium Listeria monocytogenes involves both CD4(+) and CD8(+) T cells. We used the MHC class II-presented…”
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Chemotactic responses of IL-4-, IL-10-, and IFN-gamma-producing CD4+ T cells depend on tissue origin and microbial stimulus by Debes, Gudrun F, Dahl, Martin E, Mahiny, Azita J, Bonhagen, Kerstin, Campbell, Daniel J, Siegmund, Kerstin, Erb, Klaus J, Lewis, David B, Kamradt, Thomas, Hamann, Alf

“…Th1- and Th2-polarized immune responses are crucial in the defense against pathogens but can also promote autoimmunity and allergy. The chemokine receptors…”
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Expression of selectin ligands on murine effector and IL‐10‐producing CD4+ T cells from non‐infected and infected tissues by Kretschmer, Ute, Bonhagen, Kerstin, Debes, Gudrun F., Mittrücker, Hans‐Willi, Erb, Klaus J., Liesenfeld, Oliver, Zaiss, Dietmar, Kamradt, Thomas, Syrbe, Uta, Hamann, Alf

“…Endothelial selectins are crucial for the recruitment of leukocytes into sites of inflammation. On T cells, ligands for selectins become induced upon…”
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Polyclonal expansion of adoptively transferred CD4+ alpha beta T cells in the colonic lamina propria of scid mice with colitis by Rudolphi, A, Bonhagen, K, Reimann, J

“…The adoptive transfer of low numbers of peripheral, non-fractionated CD4+ alpha beta T cells into histocompatible, severely immunodeficient (scid) hosts…”
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ICOS+ Th cells produce distinct cytokines in different mucosal immune responses by Bonhagen, Kerstin, Liesenfeld, Oliver, Stadecker, Miguel J., Hutloff, Andreas, Erb, Klaus, Coyle, Anthony J., Lipp, Martin, Kroczek, Richard A., Kamradt, Thomas

“…T cell activation, differentiation and effector functions depend on signals delivered through the antigen‐specific TCR and non‐clonal costimulatory receptors…”
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CC Chemokine Receptor 7 Expression by Effector/Memory CD4 super(+) T Cells Depends on Antigen Specificity and Tissue Localization during Influenza A Virus Infection by Debes, G F, Bonhagen, K, Wolff, T, Kretschmer, U, Krautwald, S, Kamradt, T, Hamann, A

“…The lung is an important entry site for respiratory pathogens such as influenza A virus. In order to combat such invading infectious agents, effector/memory T…”
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Colitis-Inducing Potency of CD4+ T Cells in Immunodeficient, Adoptive Hosts Depends on Their State of Activation, IL-12 Responsiveness, and CD45RB Surface Phenotype by Claesson, Mogens H, Bregenholt, Soren, Bonhagen, Kerstin, Thoma, Stefan, Moller, Peter, Grusby, Michael J, Leithauser, Frank, Nissen, Mogens H, Reimann, Jorg

“…We studied the induction, severity and rate of progression of inflammatory bowel disease (IBD) induced in SCID mice by the adoptive transfer of low numbers of…”
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Organ-Specific CD4 super(+) T Cell Response During Listeria monocytogenes Infection by Kursar, M, Bonhagen, K, Koehler, A, Kamradt, T, Kaufmann, SHE, Mittruecker, H

“…The immune response against the intracellular bacterium Listeria monocytogenes involves both CD4 super(+) and CD8 super(+) T cells. We used the MHC class…”
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Expression of ICOS In Vivo Defines CD4 super(+) Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10 by Loehning, M, Hutloff, A, Kallinich, T, Mages, H W, Bonhagen, K, Radbruch, A, Hamelmann, E, Kroczek, R A

“…The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did not yield information on the…”
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