Search Results - "BONDER, C. S."

Differential responses of human monocytes and macrophages to IL-4 and IL-13 by Hart, Prue H., Bonder, Claudine S., Balogh, Julianna, Dickensheets, Harold L., Donnelly, Raymond P., Finlay‐Jones, John J.

“…The primary interleukin‐4 (IL‐4) receptor complex on monocytes (type I IL‐4 receptor) includes the 140‐kDa α chain (IL‐4Rα) and the IL‐2 receptor γ chain, γc,…”
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Interleukin‐4 regulation of human monocyte and macrophage interleukin‐10 and interleukin‐12 production. Role of a functional interleukin‐2 receptor γ‐chain by Bonder, C S, Finlay-Jones, J J, Hart, P H

“…Interleukin‐4 (IL‐4) is the prototypic type 2 immunoregulatory cytokine that can suppress the production of many monocyte and macrophage pro‐inflammatory…”
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Essential Role for Neutrophil Recruitment to the Liver in Concanavalin A-Induced Hepatitis by Bonder, Claudine S, Ajuebor, Maureen N, Zbytnuik, Lori D, Kubes, Paul, Swain, Mark G

“…Leukocyte infiltration into the liver is paramount to the development of liver injury in hepatitis. Hepatitis occurring after the administration of Con A in…”
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Regulation of surface and soluble TNF receptor expression on human monocytes and synovial fluid macrophages by IL-4 and IL-10 by Hart, PH, Hunt, EK, Bonder, CS, Watson, CJ, Finlay-Jones, JJ

“…By regulating monocyte and macrophage production of IL-1, its receptor, and its receptor antagonist, IL-4 and IL-10 may exert significant anti-inflammatory…”
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Control of major histocompatibility complex class II expression on human monocytes by interleukin‐4: regulatory effect of lipopolysaccharide by HART, P. H., BONDER, C. S., JONES, C. A., FINLAY‐JONES, J. J.

“…Interleukin‐4 (IL‐4), like interferon‐γ (IFN‐γ), stimulates monocyte major histocompatibility complex (MHC) class II expression and thus, by increasing antigen…”
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Interleukin (IL)-10, but not IL-4 or IL-13, inhibits cytokine production and growth in juvenile myelomonocytic leukemia cells by IVERSEN, P. O, HART, P. H, BONDER, C. S, LOPEZ, A. F

“…Juvenile myelomonocytic leukemia (JMML) carries a poor prognosis. The endogenous production of cytokines by the JMML cells contributes to their growth and…”
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A28 EXOSOMES AND MICRORNA: Culture Of Pah Peripheral Blood Derived Endothelial Progenitor Cells Allows Isolation Of Exosomes And Analysis Of Their Surface Markers by Harper, R, Cockshell, M, Bonder, C S, Reynolds, P N

“…Conclusions: We have successfully cultured EPCs from 15mL of PAH patient peripheral blood as well as establishing a protocol to isolate and characterise Exo's…”
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P5384Postnatal mouse aorta contains yolk sac-derived haemangioblasts with myeloid and endothelial plasticity and vasculogenic capacity by Williamson, A, Toledo, D F, Schwarz, N, Fernando, S, Dimasi, C, Liyanage, S, Skoumbourdis, T, Chandrakanthan, V, Di Bartolo, B, Tan, J T M, Bonder, C S, Nicholls, S J, Bursill, C A, Psaltis, P J

“…Abstract Background Macrophages and endothelial cells share an intimate relationship during neovessel formation in different pathophysiological conditions…”
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Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production by Bonder, C S, Dickensheets, H L, Finlay-Jones, J J, Donnelly, R P, Hart, P H

“…IL-4 has potent anti-inflammatory properties on monocytes and suppresses both IL-1beta and TNF-alpha production. Well-characterized components of the IL-4…”
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Diminished responses to IL-13 by human monocytes differentiated in vitro: role of the IL-13R alpha 1 chain and STAT6 by Hart, PH, Bonder, C S, Balogh, J, Dickensheets, H L, Vazquez, N, Davies, KVL, Finlay-Jones, J J, Donnelly, R P

“…The primary IL-13 receptor complex on human monocytes is believed to be a heterodimer comprised of the IL-4R alpha chain and the IL-2R gamma chain ( gamma…”
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IFN-gamma downregulates interleukin-4 functional activity on monocytes by multiple mechanisms by Bonder, Claudine S, Davies, Kate V L, Hosszu, Emma K, Finlay-Jones, John J, Hart, Prue H

“…Interleukin-4 (IL-4) has potent anti-inflammatory properties on monocytes and suppresses lipopolysaccharide (LPS)-induced tumor necrosis factor-alpha…”
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Mast Cells Regulate the Magnitude and the Cytokine Microenvironment of the Contact Hypersensitivity Response by Norman, M. Ursula, Hwang, John, Hulliger, Sara, Bonder, Claudine S, Yamanouchi, Jun, Santamaria, Pere, Kubes, Paul

“…The role that mast cells play during contact hypersensitivity (CS) response is unclear because some studies have shown that mast cell-deficient mice have…”
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Characterization of IL-4 Receptor Components Expressed on Monocytes and Monocyte-derived Macrophages: Variation Associated with Differential Signaling by IL-4 by Bonder, Claudine S., Hart, Prue H., Davies, Kate V.L., Buriuy, Linda C., Finlay-Jones, John J., Woodcock, Joanna M.

“…Abstract The anti-inflammatory effects of IL-4 on activated monocytes differ from those on monocyte-derived macrophages (MDMac). While IL-4 suppresses…”
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SPHINGOSINE KINASE IN PANCREATIC ISLET TRANSPLANTATION: 282 by Jessup, C. F., Drogemuller, C. J., Mohanasundaram, D. M., Mee, C., Milner, C. R., Bonder, C. S., Coates, P. T.

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Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs by Andonegui, Graciela, Bonder, Claudine S., Green, Francis, Mullaly, Sarah C., Zbytnuik, Lori, Raharjo, Eko, Kubes, Paul

“…The rapid and selective accumulation of neutrophils into the lungs is thought to underlie the pulmonary failure that leads to sepsis-related death. In this…”
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A low-fouling polymer coating combined with key biomolecules as an endothelial cell selective platform for stents by Burzava, AL, Moore, E, Cockshell, MP, Harding, FJ, Bonder, CS, Voelcker, N

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329 - A low-fouling polymer coating combined with key biomolecules as an endothelial cell selective platform for stents by Burzava, AL, Moore, E, Cockshell, MP, Harding, FJ, Bonder, CS, Voelcker, N

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Rules of Recruitment for Th1 and Th2 Lymphocytes in Inflamed Liver: A Role for Alpha-4 Integrin and Vascular Adhesion Protein-1 by Bonder, Claudine S., Norman, M. Ursula, Swain, Mark G., Zbytnuik, Lori D., Yamanouchi, Jun, Santamaria, Pere, Ajuebor, Maureen, Salmi, Marko, Jalkanen, Sirpa, Kubes, Paul

“…The mechanisms that mediate the recruitment of Th1 and Th2 lymphocytes in vivo are poorly understood. We demonstrate that the mechanisms by which exogenously…”
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Use of CD44 by CD4+ Th1 and Th2 lymphocytes to roll and adhere by Bonder, Claudine S., Clark, Stephen R., Norman, M. Ursula, Johnson, Pauline, Kubes, Paul

“…Localization of circulating lymphocytes to a site of inflammation is paramount for the development and maintenance of an immune response. In vitro studies…”
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Interleukin-4 regulation of human monocyte and macrophage interleukin-10 and interleukin-12 production. Role of a functional interleukin-2 receptor (gamma)-chain by Bonder, C S, Finlay-Jones, J J, Hart, P H

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