Search Results - "BOLTZE, Carsten"

Sealing of pulmonary arteries with LigaSure: In vivo and ex vivo examinations by Lesser, Thomas G., MD, Wolfram, Frank, Boltze, Carsten, MD

“…Objective The LigaSure device has been demonstrated to be safe for systemic vessels up to 7 mm in diameter, although its use in thoracic surgery remains…”
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5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms by Schneider-Stock, Regine, Diab-Assef, Mona, Rohrbeck, Astrid, Foltzer-Jourdainne, Charlotte, Boltze, Carsten, Hartig, Roland, Schönfeld, Peter, Roessner, Albert, Gali-Muhtasib, Hala

“…Methyltransferase inhibitors commonly used in clinical trials promote tumor cell death, but their detailed cytotoxic action is not yet fully understood. A…”
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Loss of p16 Protein Defines High-Risk Patients with Gastrointestinal Stromal Tumors: A Tissue Microarray Study by SCHNEIDER-STOCK, Regine, BOLTZE, Carsten, IESALNIEKS, Igor, DIRNHOFER, Stefan, HARTMANN, Arndt, HEINRICH, Michel, MIETTINEN, Markku, ROESSNER, Albert, TORNILLO, Luigi, LASOTA, Jerzy, PETERS, Brigitte, CORLESS, Chris L, RUEMMELE, Petra, TERRACCIANO, Luigi, PROSS, Matthias, INSABATO, Luigi, DI VIZIO, Dolores

“…Despite clearly defined histologic criteria, the prediction of tumor behavior for patients with gastrointestinal stromal tumors (GIST) still poses a challenge…”
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Loss of maspin is a helpful prognosticator in colorectal cancer: a tissue microarray analysis by Boltze, Carsten

“…Mammary serpin (Maspin) belongs to the serine protease inhibitor (serpin) superfamily and has been identified as a tumor suppressor. In addition, a…”
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Expression and Regulation of CD97 in Colorectal Carcinoma Cell Lines and Tumor Tissues by Steinert, Matthias, Wobus, Manja, Boltze, Carsten, Schütz, Alexander, Wahlbuhl, Mandy, Hamann, Jörg, Aust, Gabriela

“…The expression of CD97, a member of the EGF-TM7 family with adhesive properties, is proportional to the aggressiveness and lymph node involvement in thyroid…”
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Loss of maspin is a helpful prognosticator in colorectal cancer: a tissue microarray analysis by Boltze, Carsten

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Effects of Radiofrequency Ablation on Normal Lung Tissue in a Swine Model by Lesser, Thomas G., MD, Ritter, Frank, MD, Schlosser, Hilmar, MD, Boltze, Carsten, MD, Hackenbroich, Christoph, MD

“…Rationale and Objectives To determine the effect of radiofrequency (RF) ablation on normal lung tissue in an animal model. Materials and Methods RF ablation of…”
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Expression Profile of the Telomeric Complex Discriminates between Benign and Malignant Pheochromocytoma by Boltze, Carsten, Mundschenk, Jochen, Unger, Nicole, Schneider-Stock, Regine, Peters, Brigitte, Mawrin, Christian, Hoang-Vu, Cuong, Roessner, Albert, Lehnert, Hendrik

“…Telomerase, a ribonucleoprotein complex that includes the telomerase RNA component, the telomerase-associated protein (TP1), the telomerase catalytic subunit…”
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Expression of matrix metalloproteinases-1, -2, and -9; tissue inhibitors of matrix metalloproteinases-1 and -2; cathepsin B; urokinase plasminogen activator; and plasminogen activator inhibitor, type I in skull base chordoma by Naka, Takahiko, MD, Kuester, Doerthe, MD, Boltze, Carsten, MD, Schulz, Torss-Oliver, MD, Samii, Amir, MD, Herold, Christian, MD, Ostertag, Helmut, MD, Roessner, Albert, MD

“…Summary Little is known about proteinase expression in skull base chordoma, a rare bone tumor exhibiting local invasiveness. Using immunohistochemical…”
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Selective Loss of Codon 72 Proline p53 and Frequent Mutational Inactivation of the Retained Arginine Allele in Colorectal Cancer by Schneider-Stock, Regine, Boltze, Carsten, Peters, Brigitte, Szibor, Reinhard, Landt, Olfert, Meyer, Frank, Roessner, Albert

“…According to recent reports, some cancer types exhibit nonrandom allele loss at codon 72 in exon 4 of the p53 gene [coding for proline (72Pro) or arginine…”
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Intraperitoneal versus intravenous CPT-11 given intra- and postoperatively for peritoneal carcinomatosis in a rat model by Hribaschek, Arndt, Kuhn, Roger, Pross, Matthias, Meyer, Frank, Fahlke, Jörg, Ridwelski, Karsten, Boltze, Carsten, Lippert, Hans

“…Peritoneal recurrence after resection of colorectal carcinoma is still a major concern. We investigated whether the novel cytostatic drug, CPT-11 (Irinotecan),…”
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Solitary Fibrous Tumors/Hemangiopericytomas with Different Variants of the NAB2 - STAT6 Gene Fusion Are Characterized by Specific Histomorphology and Distinct Clinicopathological Features by Barthelmeß, Sarah, Geddert, Helene, Boltze, Carsten, Moskalev, Evgeny A, Bieg, Matthias, Sirbu, Horia, Brors, Benedikt, Wiemann, Stefan, Hartmann, Arndt, Agaimy, Abbas, Haller, Florian

“…Recurrent somatic fusions of the two genes, NGFI-A–binding protein 2 ( NAB2 ) and STAT6 , located at chromosomal region 12q13, have been recently identified to…”
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Prognostic Value of MMP-2, -9 and TIMP-1,-2 Immunoreactive Protein at the Invasive Front in Advanced Head and Neck Squamous Cell Carcinomas by Ondruschka, Constanze, Buhtz, Peter, Motsch, Christiane, Freigang, Bernd, Schneider-Stock, Regine, Roessner, Albert, Boltze, Carsten

“…In head and neck cancer as well as in other carcinomas, tumor expansion and spread to distant sites require the secretion of destructive enzymes that degrade…”
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Intermuscular Chondrolipoma of the Thigh: The Diagnostic Way of a Rare Entity by Boltze, Carsten, Hribaschek, Arndt, Lippert, Hans, Roessner, Albert

“…Cartilaginous metaplasia in lipomas (chondrolipoma) is rare and mainly encountered in large-sized, long-standing lipomas. Chondrolipomas can be found at almost…”
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CD97, CD95 and Fas-L clearly discriminate between chronic pancreatitis and pancreatic ductal adenocarcinoma in perioperative evaluation of cryocut sections by Boltze, Carsten, Schneider-Stock, Regine, Aust, Gabi, Marwin, Christian, Dralle, Henning, Roessner, Albert, Hoang-Vu, Cuong

“…It is a major problem to distinguish between pancreatitis and pancreatic adenocarcinoma when it comes to the perioperative evaluation of pancreatic cryocut…”
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High Prognostic Value of p16INK4 Alterations in Gastrointestinal Stromal Tumors by SCHNEIDER-STOCK, Regine, BOLTZE, Carsten, LASOTA, Jerzy, MIETTINEN, Markku, PETERS, Brigitte, PROSS, Matthias, ROESSNER, Albert, GÜNTHER, Thomas

“…Gastrointestinal stromal tumors (GISTs) represent a distinctive (but histologically heterogeneous) group of neoplasms, the malignant potential of which is…”
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p16 INK4A Alterations are accompanied by aberrant protein immunostaining in endometrial carcinomas by Semczuk, Andrzej, Boltze, Carsten, Marzec, Barbara, Szczygielska, Anna, Roessner, Albert, Schneider-Stock, Regine

“…Purpose To date, the significance of p16INK4A tumor suppressor gene inactivation in sporadic endometrial cancer (EC) has only rarely been described. In this…”
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Recurrent Mutations within the Amino-Terminal Region of β-Catenin Are Probable Key Molecular Driver Events in Sinonasal Hemangiopericytoma by Haller, Florian, Bieg, Matthias, Moskalev, Evgeny A, Barthelmeß, Sarah, Geddert, Helene, Boltze, Carsten, Diessl, Nicolle, Braumandl, Karin, Brors, Benedikt, Iro, Heinrich, Hartmann, Arndt, Wiemann, Stefan, Agaimy, Abbas

“…Sinonasal hemangiopericytoma (SN-HPC) is an uncommon, site-specific, low-grade mesenchymal neoplasm of probable perivascular myoid cell origin. In contrast to…”
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Phenotypical and molecular distinctness of sinonasal haemangiopericytoma compared to solitary fibrous tumour of the sinonasal tract by Agaimy, Abbas, Barthelmeß, Sarah, Geddert, Helene, Boltze, Carsten, Moskalev, Evgeny A., Koch, Michael, Wiemann, Stefan, Hartmann, Arndt, Haller, Florian

“…Aims Sinonasal haemangiopericytoma (SN‐HPC) is a rare sinonasal mesenchymal neoplasm of perivascular myoid cell origin. Solitary fibrous tumour (SFT) occurs…”
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Effect of lung flooding and high-intensity focused ultrasound on lung tumours: an experimental study in an ex vivo human cancer model and simulated in vivo tumours in pigs by Wolfram, Frank, Boltze, Carsten, Schubert, Harald, Bischoff, Sabine, Lesser, Thomas Günther

“…High-intensity focused ultrasound is a valuable tool for minimally invasive tumour ablation. However, due to the air content in ventilated lungs, lung tumours…”
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