Search Results - "BOLOGNA, G"

The diversity, biogenesis, and activities of endogenous silencing small RNAs in Arabidopsis by Bologna, Nicolas G, Voinnet, Olivier

“…In eukaryotic RNA silencing, RNase-III classes of enzymes in the Dicer family process double-stranded RNA of cellular or exogenous origin into small-RNA (sRNA)…”
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Nucleo-cytosolic Shuttling of ARGONAUTE1 Prompts a Revised Model of the Plant MicroRNA Pathway by Bologna, Nicolas G., Iselin, Raphael, Abriata, Luciano A., Sarazin, Alexis, Pumplin, Nathan, Jay, Florence, Grentzinger, Thomas, Dal Peraro, Matteo, Voinnet, Olivier

“…Unlike in metazoans, plant microRNAs (miRNAs) undergo stepwise nuclear maturation before engaging cytosolic, sequence-complementary transcripts in association…”
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Multiple RNA recognition patterns during microRNA biogenesis in plants by Bologna, Nicolás G, Schapire, Arnaldo L, Zhai, Jixian, Chorostecki, Uciel, Boisbouvier, Jerome, Meyers, Blake C, Palatnik, Javier F

“…MicroRNAs (miRNAs) derive from longer precursors with fold-back structures. While animal miRNA precursors have homogenous structures, plant precursors comprise…”
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Identification of MicroRNA Processing Determinants by Random Mutagenesis of Arabidopsis MIR172a Precursor by Mateos, Julieta L., Bologna, Nicolás G., Chorostecki, Uciel, Palatnik, Javier F.

“…MicroRNAs (miRNAs) are widespread posttranscriptional regulators of gene expression. They are processed from longer primary transcripts that contain foldback…”
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A loop-to-base processing mechanism underlies the biogenesis of plant microRNAs miR319 and miR159 by Bologna, Nicolás G, Mateos, Julieta L, Bresso, Edgardo G, Palatnik, Javier F

“…The first step in microRNA (miRNA) biogenesis usually involves cleavage at the base of its fold‐back precursor. Here, we describe a non‐canonical processing…”
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Bacterial Infection Disrupts Clock Gene Expression to Attenuate Immune Responses by de Leone, María José, Hernando, C. Esteban, Romanowski, Andrés, Careno, Daniel A., Soverna, Ana Faigón, Sun, Hequan, Bologna, Nicolás G., Vázquez, Martín, Schneeberger, Korbinian, Yanovsky, Marcelo J.

“…The circadian clock modulates immune responses in plants and animals; however, it is unclear how host-pathogen interactions affect the clock. Here we analyzed…”
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DNA Methylation Influences the Expression of DICER-LIKE4 Isoforms, Which Encode Proteins of Alternative Localization and Function by Pumplin, Nathan, Sarazin, Alexis, Jullien, Pauline E., Bologna, Nicolas G., Oberlin, Stefan, Voinnet, Olivier

“…Plant RNA silencing operates via RNA-directed DNA-methylation (RdDM) to repress transcription or by targeting mRNAs via posttranscriptional gene silencing…”
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Arabidopsis AGO1 N-terminal extension acts as an essential hub for PRMT5 interaction and post-translational modifications by Martín-Merchán, Andrea, Lavatelli, Antonela, Engler, Camila, González-Miguel, Víctor M, Moro, Belén, Rosano, Germán L, Bologna, Nicolas G

“…Abstract Plant ARGONAUTE (AGO) proteins play pivotal roles regulating gene expression through small RNA (sRNA) -guided mechanisms. Among the 10 AGO proteins in…”
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Principles of miRNA/miRNA function in plant MIRNA processing by Rosatti, Santiago, Rojas, Arantxa M L, Moro, Belén, Suarez, Irina P, Bologna, Nicolas G, Chorostecki, Uciel, Palatnik, Javier F

“…Abstract MicroRNAs (miRNAs) are essential regulators of gene expression, defined by their unique biogenesis, which requires the precise excision of the small…”
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Identification of key sequence features required for microRNA biogenesis in plants by Rojas, Arantxa M. L., Drusin, Salvador I., Chorostecki, Uciel, Mateos, Julieta L., Moro, Belén, Bologna, Nicolas G., Bresso, Edgardo G., Schapire, Arnaldo, Rasia, Rodolfo M., Moreno, Diego M., Palatnik, Javier F.

“…MicroRNAs (miRNAs) are endogenous small RNAs of ∼21 nt that regulate multiple biological pathways in multicellular organisms. They derive from longer…”
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Structural Flexibility Enables Alternative Maturation, ARGONAUTE Sorting and Activities of miR168, a Global Gene Silencing Regulator in Plants by Iki, Taichiro, Cléry, Antoine, Bologna, Nicolas G., Sarazin, Alexis, Brosnan, Christopher A., Pumplin, Nathan, Allain, Frédéric H.T., Voinnet, Olivier

“…In eukaryotes, the RNase-III Dicer often produces length/sequence microRNA (miRNA) variants, called “isomiRs”, owing to intrinsic structural/sequence…”
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Processing of plant microRNA precursors by Bologna, Nicolás G, Schapire, Arnaldo L, Palatnik, Javier F

“…MicroRNAs are endogenous small RNAs known to be key regulators of gene expression in animals and plants. They are defined by their specific biogenesis which…”
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P103 PRE-ACT: Prediction of Radiotherapy side Effects using explainable AI for patient Communication and Treatment modification by Rattay, T., Bajardi, P., Bologna, G., Bonchi, F., Cortellessa, G., Dekker, A., Fracasso, F., Joore, M., Paragios, N., Rivera, S., Roumen, C., van Soest, J., Traverso, A., Verhoeven, K., Koutsopoulos, I., Talbot, C.J.

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Identification of new microRNA-regulated genes by conserved targeting in plant species by Chorostecki, Uciel, Crosa, Valeria A, Lodeyro, Anabella F, Bologna, Nicolás G, Martin, Ana P, Carrillo, Néstor, Schommer, Carla, Palatnik, Javier F

“…MicroRNAs (miRNAs) are major regulators of gene expression in multicellular organisms. They recognize their targets by sequence complementarity and guide them…”
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Second Double-Stranded RNA Binding Domain of Dicer-like Ribonuclease 1: Structural and Biochemical Characterization by Burdisso, Paula, Suarez, Irina P, Bologna, Nicolás G, Palatnik, Javier F, Bersch, Beate, Rasia, Rodolfo M

“…Dicer-like ribonuclease III enzymes are involved in different paths related to RNA silencing in plants. Little is known about the structural aspects of these…”
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Nuclear RNA purification by flow cytometry to study nuclear processes in plants by Moro, Belén, Kisielow, Malgorzata, Borrero, Veronica Barragan, Bouet, Antoine, Brosnan, Christopher A., Bologna, Nicolás G.

“…The nature of plant tissues has continuously hampered understanding of the spatio-temporal and subcellular distribution of RNA-guided processes. Here, we…”
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Circulating Cancer Stem Cell-Derived Extracellular Vesicles as a Novel Biomarker for Clinical Outcome Evaluation by Brocco, D., Lanuti, P., Simeone, P., Bologna, G., Pieragostino, D., Cufaro, M. C., Graziano, V., Peri, M., Di Marino, P., De Tursi, M., Grassadonia, A., Rapposelli, I. G., Pierdomenico, L., Ercolino, E., Ciccocioppo, F., Del Boccio, P., Marchisio, M., Natoli, C., Miscia, S., Tinari, N.

“…The recent introduction of the “precision medicine” concept in oncology pushed cancer research to focus on dynamic measurable biomarkers able to predict…”
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Structural determinants of Arabidopsis thaliana Hyponastic leaves 1 function in vivo by Burdisso, Paula, Milia, Fernando, Schapire, Arnaldo L, Bologna, Nicolás G, Palatnik, Javier F, Rasia, Rodolfo M

“…MicroRNAs have turned out to be important regulators of gene expression. These molecules originate from longer transcripts that are processed by ribonuclease…”
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A model for single and multiple knowledge based networks by Bologna, G.

“…The inherent black-box nature of neural networks is an important drawback with respect to the problem of explanation of neural network responses. Although…”
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Structure and RNA Interactions of the Plant MicroRNA Processing-Associated Protein HYL1 by Rasia, Rodolfo M, Mateos, Julieta, Bologna, Nicolás G, Burdisso, Paula, Imbert, Lionel, Palatnik, Javier F, Boisbouvier, Jerome

“…HYL1 is a double-stranded RNA binding protein involved in microRNA processing in plants. HYL1 enhances the efficiency and precision of the RNase III protein…”
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