Search Results - "BOERSMA, Wim G"

Effects of long-term tobramycin inhalation solution (TIS) once daily on exacerbation rate in patients with non-cystic fibrosis bronchiectasis by Terpstra, Lotte C., Altenburg, Josje, Bronsveld, Inez, de Kruif, Martijn D., Berk, Yvonne, Snijders, Dominic, Rozemeijer, Wouter, Heijerman, Harry G. M., Boersma, Wim G.

“…Abstract Background Use of long-term tobramycin inhalation solution (TIS) has been shown beneficial in cystic fibrosis (CF) and earlier findings also suggest a…”
Get full text

Aztreonam for inhalation solution in patients with non-cystic fibrosis bronchiectasis (AIR-BX1 and AIR-BX2): two randomised double-blind, placebo-controlled phase 3 trials by Barker, Alan F, Prof, O'Donnell, Anne E, Prof, Flume, Patrick, Prof, Thompson, Philip J, Prof, Ruzi, Jonathan D, MD, de Gracia, Javier, Prof, Boersma, Wim G, Prof, De Soyza, Anthony, MD, Shao, Lixin, MD, Zhang, Jenny, PhD, Haas, Laura, BA, Lewis, Sandra A, MS, Leitzinger, Sheila, BS, Montgomery, A Bruce, MD, McKevitt, Matthew T, PhD, Gossage, David, MD, Quittner, Alexandra L, Prof, O'Riordan, Thomas G, MD

“…Summary Background The clinical benefit of inhaled antibiotics in non-cystic fibrosis bronchiectasis has not been established in randomised controlled trials…”
Get full text

Biomarker guided antibiotic stewardship in community acquired pneumonia: A randomized controlled trial by Duijkers, Ruud, Prins, Hendrik J, Kross, Martijn, Snijders, Dominic, van den Berg, Jan W K, Werkman, Gwendolyn M, van der Veen, Nynke, Schoorl, Marianne, Bonten, Marc J M, van Werkhoven, Cornelis H, Boersma, Wim G

“…In community-acquired pneumonia (CAP), the role of biomarkers to shorten duration of antibiotic treatment has not been firmly established. We assessed the…”
Get full text

Antibiotics in acute exacerbations of COPD: the good, the bad and the ugly by Boersma, Wim G

Get full text

Treatment with inhaled antibiotics in bronchiectasis, side effects, and evaluation of the tolerance test; analysis from the BATTLE randomized controlled trial by Terpstra, Lotte C., Geest, Daphne, Bronsveld, Inez, Heijerman, Harry, Boersma, Wim G.

“…Introduction Tobramycin inhalation solution (TIS) is a treatment option for patients with frequent exacerbations of bronchiectasis. A possible side effect of…”
Get full text

Validating a clinical prediction score for Legionella-related community acquired pneumonia by Beekman, Rosalie R A L, Duijkers, Ruud R, Snijders, Dominic D, van der Eerden, Menno M, Kross, Martijn M, Boersma, Wim W G

“…Legionella-related community acquired pneumonia (CAP) is a disease with an increasing incidence and a high mortality rate, especially if empirical antibiotic…”
Get full text

Pneumococcal urinary antigen test: diagnostic yield and impact on antibiotic treatment by Laijen, Wendy, Snijders, Dominic, Boersma, Wim G

“…The pneumococcal urinary antigen test (PUAT) is commonly used for the etiological diagnosis of community-acquired pneumonia (CAP) and can be useful for…”
Get more information

Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression by Boudewijn, Ilse M, Faiz, Alen, Steiling, Katrina, van der Wiel, Erica, Telenga, Eef D, Hoonhorst, Susan J M, Ten Hacken, Nick H T, Brandsma, Corry-Anke, Kerstjens, Huib A M, Timens, Wim, Heijink, Irene H, Jonker, Marnix R, de Bruin, Harold G, Sebastiaan Vroegop, J, Pasma, Henk R, Boersma, Wim G, Wielders, Pascal, van den Elshout, Frank, Mansour, Khaled, Spira, Avrum, Lenburg, Marc E, Guryev, Victor, Postma, Dirkje S, van den Berge, Maarten

“…Nasal gene expression profiling is a promising method to characterize COPD non-invasively. We aimed to identify a nasal gene expression profile to distinguish…”
Get full text

CURB-65 Pneumonia Severity Assessment Adapted for Electronic Decision Support by Jones, Barbara E., MD, Jones, Jason, PhD, Bewick, Thomas, MD, Lim, Wei Shen, MD, Aronsky, Dominik, MD, PhD, Brown, Samuel M., MD, Boersma, Wim G., MD, van der Eerden, Menno M., MD, Dean, Nathan C., MD, FCCP

“…Background Accurate severity assessment is crucial to the initial management of community-acquired pneumonia (CAP). The CURB-65 (confusion, uremia, respiratory…”
Get full text

Relationship between biomarkers and findings on low-dose computed tomography in hospitalised patients with acute exacerbation of COPD by Prins, Hendrik J., Duijkers, Ruud, Kramer, Gerdien, Boerhout, Els, Rietema, Floris J., de Jong, Pim A., Schoorl, Marianne I., van der Werf, Tjip S., Boersma, Wim G.

“…Background Acute exacerbations of COPD (AECOPD) and community acquired pneumonia (CAP) often coexist. Although chest radiographs may differentiate between…”
Get full text

Recommendations for antibacterial therapy in adults with COVID-19 – an evidence based guideline by Sieswerda, Elske, de Boer, Mark G.J., Bonten, Marc M.J., Boersma, Wim G., Jonkers, René E., Aleva, Roel M., Kullberg, Bart-Jan, Schouten, Jeroen A., van de Garde, Ewoudt M.W., Verheij, Theo J., van der Eerden, Menno M., Prins, Jan M., Wiersinga, W. Joost

“…The Dutch Working Party on Antibiotic Policy constituted a multidisciplinary expert committee to provide evidence-based recommendation for the use of…”
Get full text

Reliability of radiographic findings and the relation to etiologic agents in community-acquired pneumonia by Boersma, Wim G., Daniels, Johannes M.A., Löwenberg, Alfred, Boeve, Willem-Jan, van de Jagt, Eric J.

“…In a clinical setting the chest radiograph is the reference standard in establishing the diagnosis of community-acquired pneumonia (CAP). This study aimed to…”
Get full text

Effect of Azithromycin Maintenance Treatment on Infectious Exacerbations Among Patients With Non–Cystic Fibrosis Bronchiectasis: The BAT Randomized Controlled Trial by Altenburg, Josje, de Graaff, Casper S, Stienstra, Ymkje, Sloos, Jacobus H, van Haren, Eric H. J, Koppers, Ralph J. H, van der Werf, Tjip S, Boersma, Wim G

“…IMPORTANCE Macrolide antibiotics have been shown beneficial in cystic fibrosis (CF) and diffuse panbronchiolitis, and earlier findings also suggest a benefit…”
Get full text

Heterogeneity of treatment response in bronchiectasis clinical trials by Sibila, Oriol, Laserna, Elena, Shoemark, Amelia, Perea, Lidia, Bilton, Diana, Crichton, Megan L, De Soyza, Anthony, Boersma, Wim G, Altenburg, Josje, Chalmers, James D

“…Recent randomised clinical trials in bronchiectasis have failed to reach their primary end-points, suggesting a need to reassess how we measure treatment…”
Get full text

CRP-guided antibiotic treatment in acute exacerbations of COPD in hospital admissions by Prins, H J, Duijkers, Ruud, van der Valk, Paul, Schoorl, Marianne, Daniels, Johannes M A, van der Werf, Tjip S, Boersma, Wim G

“…The role of antibiotics in acute exacerbations of chronic obstructive pulmonary disease (COPD) is controversial and a biomarker identifying patients who…”
Get full text

Antibiotic Treatment Strategies for Community-Acquired Pneumonia in Adults by Postma, Douwe F, van Werkhoven, Cornelis H, van Elden, Leontine J.R, Thijsen, Steven F.T, Hoepelman, Andy I.M, Kluytmans, Jan A.J.W, Boersma, Wim G, Compaijen, Clara J, van der Wall, Eva, Prins, Jan M, Oosterheert, Jan J, Bonten, Marc J.M

“…Antimicrobial choices for community-acquired pneumonia in hospitalized patients who do not require ICU-level care continue to be debated. In this trial,…”
Get full text

Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations by Aliberti, Stefano, Goeminne, Pieter C, O'Donnell, Anne E, Aksamit, Timothy R, Al-Jahdali, Hamdan, Barker, Alan F, Blasi, Francesco, Boersma, Wim G, Crichton, Megan L, De Soyza, Anthony, Dimakou, Katerina E, Elborn, Stuart J, Feldman, Charles, Tiddens, Harm, Haworth, Charles S, Hill, Adam T, Loebinger, Michael R, Martinez-Garcia, Miguel Angel, Meerburg, Jennifer J, Menendez, Rosario, Morgan, Lucy C, Murris, Marlene S, Polverino, Eva, Ringshausen, Felix C, Shteinberg, Michal, Sverzellati, Nicola, Tino, Gregory, Torres, Antoni, Vandendriessche, Thomas, Vendrell, Montserrat, Welte, Tobias, Wilson, Robert, Wong, Conroy A, Chalmers, James D

“…Bronchiectasis refers to both a clinical disease and a radiological appearance that has multiple causes and can be associated with a range of conditions…”
Get full text

A man with swollen eyelids by Boersma, Anton R, Boersma, Wim G

“…A 74-old man developed severe periorbital emphysema after a video-assisted thoracoscopy for lung malignancy. Because of severe symptoms of pain and visual…”
Get more information

Bacillus Calmette-Guérin vaccine to reduce healthcare worker absenteeism in COVID-19 pandemic, a randomized controlled trial by ten Doesschate, Thijs, van der Vaart, Thomas W., Debisarun, Priya A., Taks, Esther, Moorlag, Simone J.C.F.M., Paternotte, Nienke, Boersma, Wim G., Kuiper, Vincent P., Roukens, Anna H.E., Rijnders, Bart J.A., Voss, Andreas, Veerman, Karin M., Kerckhoffs, Angele P.M., Oever, Jaap ten, van Crevel, Reinout, van Nieuwkoop, Cees, Lalmohamed, Arief, van de Wijgert, Janneke H.H.M., Netea, Mihai G., Bonten, Marc J.M., van Werkhoven, Cornelis H.

“…The COVID-19 pandemic increases healthcare worker (HCW) absenteeism. The bacillus Calmette-Guérin (BCG) vaccine may provide non-specific protection against…”
Get full text

Efficacy of Corticosteroids in Community-acquired Pneumonia: A Randomized Double-Blinded Clinical Trial by SNIJDERS, Dominic, DANIELS, Johannes M. A, DE GRAAFF, Casper S, VAN DER WERF, Tjip S, BOERSMA, Wim G

“…Some studies have shown a beneficial effect of corticosteroids in patients with community-acquired pneumonia (CAP), possibly by diminishing local and systemic…”
Get full text