Search Results - "BOEPPLE, Paul A"

Reversal and Relapse of Hypogonadotropic Hypogonadism: Resilience and Fragility of the Reproductive Neuroendocrine System by Sidhoum, Valerie F, Chan, Yee-Ming, Lippincott, Margaret F, Balasubramanian, Ravikumar, Quinton, Richard, Plummer, Lacey, Dwyer, Andrew, Pitteloud, Nelly, Hayes, Frances J, Hall, Janet E, Martin, Kathryn A, Boepple, Paul A, Seminara, Stephanie B

“…Context: A subset of patients diagnosed with idiopathic hypogonadotropic hypogonadism (IHH) later achieves activation of their hypothalamic-pituitary-gonadal…”
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Comparison of Short and Long-Term Outcomes of Metabolic and Bariatric Surgery in Adolescents and Adults by Stanford, Fatima Cody, Mushannen, Tasnim, Cortez, Priscilla, Campoverde Reyes, Karen J, Lee, Hang, Gee, Denise W, Pratt, Janey S, Boepple, Paul A, Bredella, Miriam A, Misra, Madhusmita, Singhal, Vibha

“…We sought to compare the short and long-term outcomes of MBS in adolescents vs. adults who have undergone a Roux-en-Y gastric bypass (RYGB) or Sleeve…”
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Safety of Frequent Venous Blood Sampling in a Pediatric Research Population by Broder-Fingert, Sarabeth, MA, Crowley, William F., MD, Boepple, Paul A., MD

“…Objective To monitor hematological indices in otherwise healthy children with central precocious puberty who underwent frequent venous sampling as part of a…”
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Trial of Recombinant Follicle-Stimulating Hormone Pretreatment for GnRH-Induced Fertility in Patients with Congenital Hypogonadotropic Hypogonadism by Dwyer, Andrew A, Sykiotis, Gerasimos P, Hayes, Frances J, Boepple, Paul A, Lee, Hang, Loughlin, Kevin R, Dym, Martin, Sluss, Patrick M, Crowley, William F, Pitteloud, Nelly

“…Context and Objective: The optimal strategy for inducing fertility in men with congenital hypogonadotropic hypogonadism (CHH) is equivocal. Albeit a…”
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A Genetic Basis for Functional Hypothalamic Amenorrhea by Caronia, Lisa M, Martin, Kathryn A, Martin, Cecilia, Welt, Corrine K, Sykiotis, Gerasimos P, Quinton, Richard, Thambundit, Apisadaporn, Avbelj, Magdalena, Dhruvakumar, Sadhana, Plummer, Lacey, Hughes, Virginia A, Seminara, Stephanie B, Boepple, Paul A, Sidis, Yisrael, Crowley, William F, Hall, Janet E, Pitteloud, Nelly

“…The authors hypothesized that mutations in genes involved in idiopathic hypogonadotropic hypogonadism would be associated with functional hypothalamic…”
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Adult-Onset Idiopathic Hypogonadotropic Hypogonadism — A Treatable Form of Male Infertility by Nachtigall, Lisa B, Boepple, Paul A, Pralong, François P, Crowley, William F

“…Men with idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome (idiopathic hypogonadotropic hypogonadism and anosmia) have severe…”
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Inhibition of Luteinizing Hormone Secretion by Testosterone in Men Requires Aromatization for Its Pituitary But Not Its Hypothalamic Effects: Evidence from the Tandem Study of Normal and Gonadotropin-Releasing Hormone-Deficient Men by Pitteloud, Nelly, Dwyer, Andrew A., DeCruz, Suzzunne, Lee, Hang, Boepple, Paul A., Crowley, William F., Hayes, Frances J.

“…Context: Studies on the regulation of LH secretion by sex steroids in men are conflicting. Objective: Our aims were to determine the relative contributions of…”
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Interplay between dose and frequency of GnRH administration in determining pituitary gonadotropin responsiveness by Hughes, Virginia A, Boepple, Paul A, Crowley, Jr, William F, Seminara, Stephanie B

“…The dose, frequency and contour of GnRH stimulation of the pituitary gonadotrope have been shown to be independent variables influencing pituitary LH…”
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The Relative Role of Gonadal Sex Steroids and Gonadotropin-Releasing Hormone Pulse Frequency in the Regulation of Follicle-Stimulating Hormone Secretion in Men by Pitteloud, Nelly, Dwyer, Andrew A., DeCruz, Suzzunne, Lee, Hang, Boepple, Paul A., Crowley, William F., Hayes, Frances J.

“…Objective: Our objective was to determine the importance of testosterone (T), estradiol (E2), and GnRH pulse frequency to FSH regulation in men. Design: This…”
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Case 12-2015: A Newborn Boy with Respiratory Distress, Lethargy, and Hypernatremia by Lin, Ting-Yi, Ebb, David H, Boepple, Paul A, Thiele, Elizabeth A, Rincon, Sandra P, Mordes, Daniel A

“…A newborn boy was admitted to the hospital because of respiratory distress and hypotension. At delivery, meconium was suctioned from the airway. Respiration…”
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Predictors of Outcome of Long-Term GnRH Therapy in Men with Idiopathic Hypogonadotropic Hypogonadism by Pitteloud, Nelly, Hayes, Frances J., Dwyer, Andrew, Boepple, Paul A., Lee, Hang, Crowley, William F.

“…GnRH treatment is successful in inducing virilization and spermatogenesis in men with idiopathic hypogonadotropic hypogonadism (IHH). However, a small subset…”
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The Role of Prior Pubertal Development, Biochemical Markers of Testicular Maturation, and Genetics in Elucidating the Phenotypic Heterogeneity of Idiopathic Hypogonadotropic Hypogonadism by Pitteloud, Nelly, Hayes, Frances J., Boepple, Paul A., DeCruz, Suzzunne, Seminara, Stephanie B., MacLaughlin, David T., Crowley, William F.

“…As our knowledge of the molecular mechanisms underlying idiopathic hypogonadotropic hypogonadism (IHH) expands, it becomes increasingly important to define the…”
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Metabolic Effects of Roux‐en‐Y Gastric Bypass in Obese Adolescents and Young Adults by Sinha, Manasi, Stanley, Takara L., Webb, Jessica, Scirica, Christina, Corey, Kathleen, Pratt, Janey, Boepple, Paul A., Hoppin, Alison, Misra, Madhusmita

“…ABSTRACT Weight loss surgery is an increasingly common treatment option for obese adolescents, but data are limited regarding the metabolic effects of surgical…”
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Relative Roles of Inhibin B and Sex Steroids in the Negative Feedback Regulation of Follicle-Stimulating Hormone in Men across the Full Spectrum of Seminiferous Epithelium Function by Boepple, Paul A., Hayes, Frances J., Dwyer, Andrew A., Raivio, Taneli, Lee, Hang, Crowley, William F., Pitteloud, Nelly

“…Context and Objective: Our aim was to explore the relative roles of gonadal sex steroids and inhibin B in the regulation of FSH across a spectrum of…”
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Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback by HAYES, Frances J, SEMINARA, Stephanie B, DECRUZ, Suzzunne, BOEPPLE, Paul A, CROWLEY, William F

“…The preponderance of evidence states that, in adult men, estradiol (E2) inhibits LH secretion by decreasing pulse amplitude and responsiveness to GnRH…”
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Adolescent obesity and bariatric surgery by Levitsky, Lynne L, Misra, Madhusmita, Boepple, Paul A, Hoppin, Alison G

“…Examines the effects of bariatric surgery on adolescent obesity. The risks and outcomes of bariatric surgery in adolescence are presently being defined and may…”
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Rathke's cleft cysts in children and adolescents: association with female puberty by Katavetin, Paravee, Cheunsuchon, Pornsuk, Grant, Ellen, Boepple, Paul A, Hedley-Whyte, E Tessa, Misra, Madhusmita, Levitsky, Lynne L

“…There are few pediatric data regarding manifestations and outcomes of Rathke's cleft cysts (RCC). We retrospectively reviewed 13 cases treated at Massachusetts…”
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Role of seminiferous tubular development in determining the FSH versus LH responsiveness to GnRH in early sexual maturation by Pitteloud, Nelly, Thambundit, Apisadaporn, Dwyer, Andrew A, Falardeau, John L, Plummer, Lacey, Caronia, Lisa M, Hayes, Frances J, Lee, Hang, Boepple, Paul A, Crowley, Jr, William F

“…The onset of sexual maturation at puberty is a unique developmental period from a neuroendocrine perspective in that it is characterized by enhanced FSH…”
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A Genetic Basis for Functional Hypothalamic Amenorrhea by Caronia, Lisa M, Martin, Cecilia, Welt, Corrine K, Sykiotis, Gerasimos P, Quinton, Richard, Thambundit, Apisadaporn, Avbelj, Magdalena, Dhruvakumar, Sadhana, Plummer, Lacey, Hughes, Virginia A, Seminara, Stephanie B, Boepple, Paul A, Sidis, Yisrael, Crowley, William F, Martin, Kathryn A, Hall, Janet E, Pitteloud, Nelly

“…Functional hypothalamic amenorrhea, a frequent cause of female infertility, is a reversible form of gonadotropin-releasing hormone (GnRH) deficiency triggered…”
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Variation in the Timing of Puberty: Clinical Spectrum and Genetic Investigation by Palmert, Mark R., Boepple, Paul A.

“…Human puberty begins with the reemergence of GnRH secretion from its relative quiescence during childhood, activating a cascade of pituitary-gonadal…”
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