Search Results - "BOENISCH, O"

Critical Role of Proinflammatory Cytokine IL‐6 in Allograft Rejection and Tolerance by Zhao, X., Boenisch, O., Yeung, M., Mfarrej, B., Yang, Sunmi, Turka, L. A., Sayegh, M. H., Iacomini, J., Yuan, X.

“…The proinflammatory cytokine IL‐6 plays an important role in controlling T‐cell differentiation, especially the development of Th17 and regulatory T cells. To…”
Get full text

The Role of Costimulatory Molecules in Directing the Functional Differentiation of Alloreactive T Helper Cells by Magee, C. N., Boenisch, O., Najafian, N.

“…Costimulatory molecules are a heterogenous group of cell surface molecules that act to amplify or counteract the initial activating signals provided to T cells…”
Get full text

Overcoming Memory T‐Cell Responses for Induction of Delayed Tolerance in Nonhuman Primates by Yamada, Y., Boskovic, S., Aoyama, A., Murakami, T., Putheti, P., Smith, R. N., Ochiai, T., Nadazdin, O., Koyama, I., Boenisch, O., Najafian, N., Bhasin, M. K., Colvin, R. B., Madsen, J. C., Strom, T. B., Sachs, D. H., Benichou, G., Cosimi, A. B., Kawai, T.

“…The presence of alloreactive memory T cells is a major barrier for induction of tolerance in primates. In theory, delaying conditioning for tolerance induction…”
Get full text

Ex Vivo Expansion of Human Tregs by Rabbit ATG Is Dependent on Intact STAT3‐Signaling in CD4+ T Cells and Requires the Presence of Monocytes by Boenisch, O., Lopez, M., Elyaman, W., Magee, C. N., Ahmad, U., Najafian, N.

“…The addition of low, nondepleting doses of rabbit antithymocyte globulin (ATG) to human peripheral blood mononuclear cells has been shown to expand functional…”
Get full text

Elimination of middle-sized uremic solutes with high-flux and high-cut-off membranes: a randomized in vivo study by Kneis, C, Beck, W, Boenisch, O, Klefisch, F, Deppisch, R, Zickler, D, Schindler, R

“…The elimination of substances between 10 and 50 kDa by conventional high-flux membranes is not satisfactory. We investigated in vivo the elimination of…”
Get more information

In Vivo Function of Immune Inhibitory Molecule B7‐H4 in Alloimmune Responses by Yamaura, K., Watanabe, T., Boenisch, O., Yeung, M., Yang, S., Magee, C. N., Padera, R., Datta, S., Schatton, T., Kamimura, Y., Azuma, M., Najafian, N.

“…B7 ligands deliver both costimulatory and coinhibitory signals to the CD28 family of receptors on T lymphocytes, the balance between which determines the…”
Get full text

Effect of the hemodialysis membrane on the inflammatory reaction in vivo by Schindler, R, Boenisch, O, Fischer, C, Frei, U

“…Increased levels of C-reactive protein (CRP), a marker of systemic inflammation, are associated with myocardial infarction, stroke and the development of…”
Get more information

Paradoxical Functions of B7: CD28 Costimulation in a MHC Class II‐Mismatched Cardiac Transplant Model by Yang, J., Riella, L.V., Boenisch, O., Popoola, J., Robles, S., Watanabe, T., Vanguri, V., Yuan, X., Guleria, I., Turka, L. A., Sayegh, M. H., Chandraker, A.

“…Blockade of the B7: CD28 costimulatory pathway has emerged as a promising therapy to prevent allograft rejection. However, this pathway has also been…”
Get full text

Differential Requirement of CD27 Costimulatory Signaling for Naïve Versus Alloantigen‐Primed Effector/Memory CD8+ T Cells by Yamaura, K., Boenisch, O., Watanabe, T., Ueno, T., Vanguri, V., Yang, J., Tanaka, K., Guleria, I., Borst, J., Zhai, Y., Kupiec‐Weglinski, J. W., Najafian, N.

“…CD8+ memory T cells endanger allograft survival by causing acute and chronic rejection and prevent tolerance induction. We explored the role of CD27:CD70…”
Get full text

Aerosolized Amphotericin B Inhalations as Prophylaxis of Invasive Aspergillus Infections During Prolonged Neutropenia: Results of a Prospective Randomized Multicenter Trial by Schwartz, S., Behre, G., Heinemann, V., Wandt, H., Schilling, E., Arning, M., Trittin, A., Kern, W.V., Boenisch, O., Bosse, D., Lenz, K., Ludwig, W.D., Hiddemann, W., Siegert, W., Beyer, J.

“…We performed a prospective, randomized, multicenter trial to evaluate the effectiveness of prophylactic inhalations with aerosolized amphotericin B (aeroAmB)…”
Get full text

29: Expansion of CD4+CD25+FoxP3+ Regulatory T Lymphocytes with Low-Dose Anti-Thymocyte Globulin Leads to Prolonged Survival of Cardiac Allografts but Not Tolerance by Millington, T.M, Boenisch, O, Boskovic, S, Najafian, N, Sayegh, M.H, Madsen, J.C

Get full text

Aerosol amphotericin B inhalations for prevention of invasive pulmonary aspergillosis in neutropenic cancer patients by BEHRE, G. F, SCHWARTZ, S, TREDER, W, SIEGERT, W, HIDDEMANN, W, BEYER, J, LENZ, K, LUDWIG, W.-D, WANDT, H, SCHILLING, E, HEINEMANN, V, LINK, H, TRITTIN, A, BOENISCH, O

“…To determine the value of aerosol amphotericin B inhalations for prevention of invasive pulmonary aspergillosis (IPA), we initiated a prospective randomized…”
Get full text

Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock by Oppert, Michael, Schindler, Ralf, Husung, Claudia, Offermann, Katrin, Gräf, Klaus-Jürgen, Boenisch, Olaf, Barckow, Detlef, Frei, Ulrich, Eckardt, Kai-Uwe

“…OBJECTIVES:To investigate the effect of low-dose hydrocortisone on time to shock reversal, the cytokine profile, and its relation to adrenal function in…”
Get full text

Galectin 9 - a Novel Regulator of Humoral Rejection: 2306 by Boenisch, O., Watanabe, T., Snawder, B., Najafian, N.

Get full text

Blocking IL-17 Prevents The Accelerated Rejection of Older Cardiac Allografts: Abstract# 579 by Biefer, Rodriguez H. Cetina, Oberhuber, R., Boenisch, O., Quante, M., Slegtenhorst, B., Edtinger, K., Yang, X., ElKhal, A., Tullius, S.

Get full text

Residual APCs Are Critical for the More Potent Immune Response Following the Engraftment of Older Organs: 1742 by Oberhuber, R., Boenisch, O., Heinbokel, T., Hock, K., Li, H., Liu, G., Elkhal, A., Pratschke, J., Tullius, S. G.

Get full text

Residual APCs Are Critical for the More Potent Immune Response Following the Engraftment of Older Organs: 1742 by Oberhuber, R., Boenisch, O., Heinbokel, T., Hock, K., Li, H., Liu, G., Elkhal, A., Pratschke, J., Tullius, S. G.

Get full text

Differential Requirement of CD27 Costimulatory Signaling for Naïve Versus Alloantig(en‐Primed Effector/Memory CD8+ T Cells by Yamaura, K., Boenisch, O., Watanabe, T., Ueno, T., Vanguri, V., Yang, J., Tanaka, K., Guleria, I., Borst, J., Zhai, Y., Kupiec‐Weglinski, J.W., Najafian, N.

Get full text

Clinical manifestation of mannose-binding lectin deficiency in adults independent of concomitant immunodeficiency by Hoeflich, Conny, Unterwalder, Nadine, Schuett, Sabine, Schmolke, Kathrin, Boenisch, Olaf, Hammer, Markus, Scheufele, Ramona, Michael, Dagmar, Volk, Hans-Dieter, Scheibenbogen, Carmen, von Baehr, Volker, Meisel, Christian

“…Abstract Mannose-binding lectin (MBL) mediates important functions within the innate immune system, and its deficiency was associated with infectious…”
Get full text

C-reactive-protein and cytokine plasma levels in hemodialysis patients by Boenisch, Olaf, Ehmke, Klaus-Dieter, Heddergott, Adalbert, Naoum, Claudia, Frei, Ulrich, Schindler, Ralf

“…Markers of an acute phase reaction, such as C-reactive protein (CRP) or interleukin-6 (IL-6), are predictive for cardiovascular morbidity and mortality in…”
Get more information