Search Results - "BOECKXSTAENS, Guy E. E"

Achalasia by Boeckxstaens, Guy E, Prof, Zaninotto, Giovanni, Prof, Richter, Joel E, Prof

“…Summary Achalasia is a rare motility disorder of the oesophagus characterised by loss of enteric neurons leading to absence of peristalsis and impaired…”
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A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment by Van Hove, Hannah, Martens, Liesbet, Scheyltjens, Isabelle, De Vlaminck, Karen, Pombo Antunes, Ana Rita, De Prijck, Sofie, Vandamme, Niels, De Schepper, Sebastiaan, Van Isterdael, Gert, Scott, Charlotte L., Aerts, Jeroen, Berx, Geert, Boeckxstaens, Guy E., Vandenbroucke, Roosmarijn E., Vereecke, Lars, Moechars, Diederik, Guilliams, Martin, Van Ginderachter, Jo A., Saeys, Yvan, Movahedi, Kiavash

“…While the roles of parenchymal microglia in brain homeostasis and disease are fairly clear, other brain-resident myeloid cells remain less well understood. By…”
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Functional Lumen Imaging Probe for the Management of Esophageal Disorders: Expert Review From the Clinical Practice Updates Committee of the AGA Institute by Hirano, Ikuo, Pandolfino, John E, Boeckxstaens, Guy E

“…The functional luminal imaging probe is a Food and Drug Administration–approved measurement tool used to measure simultaneous pressure and diameter to guide…”
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Transient receptor potential ion channel function in sensory transduction and cellular signaling cascades underlying visceral hypersensitivity by Balemans, Dafne, Boeckxstaens, Guy E, Talavera, Karel, Wouters, Mira M

“…Visceral hypersensitivity is an important mechanism underlying increased abdominal pain perception in functional gastrointestinal disorders including…”
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Efficacy of psychotropic drugs in functional dyspepsia: systematic review and meta-analysis by Ford, Alexander C, Luthra, Pavit, Tack, Jan, Boeckxstaens, Guy E, Moayyedi, Paul, Talley, Nicholas J

“…Functional dyspepsia (FD) is a chronic gastroduodenal disorder. Individuals with FD demonstrate visceral hypersensitivity, abnormal central pain processing,…”
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Bioelectronics in the brain–gut axis: focus on inflammatory bowel disease (IBD) by Stakenborg, Nathalie, Boeckxstaens, Guy E

“…Abstract Accumulating evidence shows that intestinal homeostasis is mediated by cross-talk between the nervous system, enteric neurons and immune cells,…”
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A distinct vagal anti-inflammatory pathway modulates intestinal muscularis resident macrophages independent of the spleen by Matteoli, Gianluca, Gomez-Pinilla, Pedro J, Nemethova, Andrea, Di Giovangiulio, Martina, Cailotto, Cathy, van Bree, Sjoerd H, Michel, Klaus, Tracey, Kevin J, Schemann, Michael, Boesmans, Werend, Vanden Berghe, Pieter, Boeckxstaens, Guy E

“…The cholinergic anti-inflammatory pathway (CAIP) has been proposed as a key mechanism by which the brain, through the vagus nerve, modulates the immune system…”
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Functional characterization of oxazolone-induced colitis and survival improvement by vagus nerve stimulation by Meroni, Elisa, Stakenborg, Nathalie, Gomez-Pinilla, Pedro J, De Hertogh, Gert, Goverse, Gera, Matteoli, Gianluca, Verheijden, Simon, Boeckxstaens, Guy E

“…Oxazolone-induced colitis has been frequently used in literature as a model of IBD, but insights into the underlying immune response and pathological features…”
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Outcomes of Treatment for Achalasia Depend on Manometric Subtype by Rohof, Wout O, Salvador, Renato, Annese, Vito, Bruley des Varannes, Stanislas, Chaussade, Stanislas, Costantini, Mario, Elizalde, J. Ignasi, Gaudric, Marianne, Smout, André J, Tack, Jan, Busch, Olivier R, Zaninotto, Giovanni, Boeckxstaens, Guy E

“…Background & Aims Patients with achalasia are treated with either pneumatic dilation (PD) or laparoscopic Heller myotomy (LHM), which have comparable rates of…”
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Pneumatic Dilation versus Laparoscopic Heller's Myotomy for Idiopathic Achalasia by Boeckxstaens, Guy E, Annese, Vito, Varannes, Stanislas Bruley des, Chaussade, Stanislas, Costantini, Mario, Cuttitta, Antonello, Elizalde, J. Ignasi, Fumagalli, Uberto, Gaudric, Marianne, Rohof, Wout O, Smout, André J, Tack, Jan, Zwinderman, Aeilko H, Zaninotto, Giovanni, Busch, Olivier R

“…In patients with achalasia, symptom reduction at 2 years was not superior with laparoscopic Heller's myotomy (LHM) as compared with pneumatic dilation…”
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CCR2-dependent monocyte-derived macrophages resolve inflammation and restore gut motility in postoperative ileus by Farro, Giovanna, Stakenborg, Michelle, Gomez-Pinilla, Pedro J, Labeeuw, Evelien, Goverse, Gera, Di Giovangiulio, Martina, Stakenborg, Nathalie, Meroni, Elisa, D'Errico, Francesca, Elkrim, Yvon, Laoui, Damya, Lisowski, Zofia M, Sauter, Kristin A, Hume, David A, Van Ginderachter, Jo A, Boeckxstaens, Guy E, Matteoli, Gianluca

“…Postoperative ileus (POI) is assumed to result from myeloid cells infiltrating the intestinal (ME) in patients undergoing abdominal surgery. In the current…”
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Vagus nerve stimulation dampens intestinal inflammation in a murine model of experimental food allergy by Bosmans, Goele, Appeltans, Iris, Stakenborg, Nathalie, Gomez‐Pinilla, Pedro J., Florens, Morgane V., Aguilera‐Lizarraga, Javier, Matteoli, Gianluca, Boeckxstaens, Guy E.

“…Background The vagus nerve has emerged as an important modulator of the intestinal immune system. Its anti‐inflammatory properties have been previously shown…”
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Revisiting Epidemiologic Features of Achalasia by Boeckxstaens, Guy E., MD, PhD

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Neuro-anatomical evidence indicating indirect modulation of macrophages by vagal efferents in the intestine but not in the spleen by Cailotto, Cathy, Gomez-Pinilla, Pedro J, Costes, Léa M, van der Vliet, Jan, Di Giovangiulio, Martina, Némethova, Andrea, Matteoli, Gianluca, Boeckxstaens, Guy E

“…Electrical stimulation of the vagus nerve suppresses intestinal inflammation and normalizes gut motility in a mouse model of postoperative ileus. The exact…”
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The Neuromodulation of the Intestinal Immune System and Its Relevance in Inflammatory Bowel Disease by Di Giovangiulio, Martina, Verheijden, Simon, Bosmans, Goele, Stakenborg, Nathalie, Boeckxstaens, Guy E, Matteoli, Gianluca

“…One of the main tasks of the immune system is to discriminate and appropriately react to "danger" or "non-danger" signals. This is crucial in the…”
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Treatment of abdominal pain in irritable bowel syndrome by Vanuytsel, Tim, Tack, Jan F., Boeckxstaens, Guy E.

“…Functional abdominal pain in the context of irritable bowel syndrome (IBS) is a challenging problem for primary care physicians, gastroenterologists and pain…”
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Cholinergic Modulation of Type 2 Immune Responses by Bosmans, Goele, Shimizu Bassi, Gabriel, Florens, Morgane, Gonzalez-Dominguez, Erika, Matteoli, Gianluca, Boeckxstaens, Guy E

“…In recent years, the bidirectional relationship between the nervous and immune system has become increasingly clear, and its role in both homeostasis and…”
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Enteric glial cells favor accumulation of anti-inflammatory macrophages during the resolution of muscularis inflammation by Stakenborg, Michelle, Abdurahiman, Saeed, De Simone, Veronica, Goverse, Gera, Stakenborg, Nathalie, van Baarle, Lies, Wu, Qin, Pirottin, Dimitri, Kim, Jung-Seok, Chappell-Maor, Louise, Pintelon, Isabel, Thys, Sofie, Pollenus, Emilie, Boon, Louis, Van den Steen, Philippe, Hao, Marlene, Van Ginderachter, Jo A., Boeckxstaens, Guy E., Timmermans, Jean-Pierre, Jung, Steffen, Marichal, Thomas, Ibiza, Sales, Matteoli, Gianluca

“…Monocyte-derived macrophages (Mφs) are crucial regulators during muscularis inflammation. However, it is unclear which micro-environmental factors are…”
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Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway by de Jonge, Wouter J, van der Zanden, Esmerij P, The, Frans O, Bijlsma, Maarten F, van Westerloo, David J, Bennink, Roelof J, Berthoud, Hans-Rudolf, Uematsu, Satoshi, Akira, Shizuo, van den Wijngaard, Rene M, Boeckxstaens, Guy E

“…Acetylcholine released by efferent vagus nerves inhibits macrophage activation. Here we show that the anti-inflammatory action of nicotinic receptor activation…”
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Nicotine attenuates activation of tissue resident macrophages in the mouse stomach through the β2 nicotinic acetylcholine receptor by Nemethova, Andrea, Michel, Klaus, Gomez-Pinilla, Pedro J, Boeckxstaens, Guy E, Schemann, Michael

“…The cholinergic anti-inflammatory pathway is an endogenous mechanism by which the autonomic nervous system attenuates macrophage activation via nicotinic…”
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