Search Results - "BODO, M"
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A proposal for the future of scientific publishing in the life sciences
Published in PLoS biology (12-02-2019)“…Science advances through rich, scholarly discussion. More than ever before, digital tools allow us to take that dialogue online. To chart a new future for open…”
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Mini-batch optimization enables training of ODE models on large-scale datasets
Published in Nature communications (10-01-2022)“…Quantitative dynamic models are widely used to study cellular signal processing. A critical step in modelling is the estimation of unknown model parameters…”
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Intra-population terpene polymorphism of Thymus pulegioides L.: Evidence for seven chemotypes in a German limestone grassland
Published in Biochemical systematics and ecology (01-12-2020)“…For Thymus pulegioides L. (Lamiaceae), occurring in almost entire Europe, about 20 different essential oil chemotypes are described in approximately 25…”
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Proteomic and functional analysis of the mitotic Drosophila centrosome
Published in The EMBO journal (06-10-2010)“…Regulation of centrosome structure, duplication and segregation is integrated into cellular pathways that control cell cycle progression and growth. As part of…”
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Using vegetation attributes to rapidly assess degradation of East African wetlands
Published in Ecological indicators (01-06-2018)“…•Anthropogenic disturbances modify vegetation structure in wetlands.•We used vegetation attributes in regression models to predict degradation of…”
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Long term effects of cigarette smoke extract or nicotine on nerve growth factor and its receptors in a bronchial epithelial cell line
Published in Toxicology in vitro (01-12-2018)“…Long-term exposure to cigarette smoke induces severe injuries to respiratory system through several mechanisms, some of them are well defined, but many others…”
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Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins
Published in PLoS computational biology (01-11-2022)“…The clustering of platelet glycoprotein receptors with cytosolic YxxL and YxxM motifs, including GPVI, CLEC-2 and PEAR1, triggers activation via…”
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Climate change influences chlorophylls and bacteriochlorophylls metabolism in hypersaline microbial mat
Published in The Science of the total environment (01-01-2022)“…This study aimed to determine the effect of the climatic change on the phototrophic communities of hypersaline microbial mats. Ocean acidification and warming…”
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Models of Models: A Translational Route for Cancer Treatment and Drug Development
Published in Frontiers in oncology (19-09-2017)“…Every patient and every disease is different. Each patient therefore requires a personalized treatment approach. For technical reasons, a personalized approach…”
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Carbon accrual rates, vegetation and nutrient dynamics in a regularly burned coppice woodland in Germany
Published in Global change biology. Bioenergy (01-06-2017)“…Historically, large areas of forest in Europe were managed as coppice woodland to produce wood‐based fuel for the smelting industry. We hypothesized that this…”
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Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma
Published in Cancer research (Chicago, Ill.) (01-11-2016)“…Hypofertility is a risk factor for the development of testicular germ cell tumors (TGCT), but the initiating event linking these pathologies is unknown. We…”
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The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors
Published in Molecular cancer (16-05-2011)“…Current large-scale cancer sequencing projects have identified large numbers of somatic mutations covering an increasing number of different cancer tissues and…”
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Miniaturization in functional genomics and proteomics
Published in Nature reviews. Genetics (01-06-2005)“…Proteins are the key components of the cellular machinery responsible for processing changes that are ordered by genomic information. Analysis of most human…”
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centromeric protein Sgo1 is required to sense lack of tension on mitotic chromosomes
Published in Science (American Association for the Advancement of Science) (07-01-2005)“…Chromosome alignment on the mitotic spindle is monitored by the spindle checkpoint. We identify Sgo1, a protein involved in meiotic chromosome cohesion, as a…”
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LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells
Published in Nature communications (2013)“…Centrosome morphology and number are frequently deregulated in cancer cells. Here, to identify factors that are functionally relevant for centrosome…”
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Cancer Precision Medicine: Why More Is More and DNA Is Not Enough
Published in Public health genomics (01-01-2017)“…Every tumour is different. They arise in patients with different genomes, from cells with different epigenetic modifications, and by random processes affecting…”
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Parallels of secondary grassland succession and soil regeneration in a chronosequence of central-Hungarian old fields
Published in Folia geobotanica (02-07-2015)“…This study deals with spontaneous regeneration of fen and steppe meadows and corresponding soil properties on extensively managed ex-arable fields. Our first…”
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A Pathway Containing the Ipl1/Aurora Protein Kinase and the Spindle Midzone Protein Ase1 Regulates Yeast Spindle Assembly
Published in Developmental cell (01-09-2007)“…It is critical to elucidate the pathways that mediate spindle assembly and therefore ensure accurate chromosome segregation during cell division. Our studies…”
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Higher frequency of genetic variants conferring increased risk for ADRs for commonly used drugs treating cancer, AIDS and tuberculosis in persons of African descent
Published in The pharmacogenomics journal (01-04-2014)“…There is established clinical evidence for differences in drug response, cure rates and survival outcomes between different ethnic populations, but the causes…”
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