Search Results - "BODE, Arthur P"
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Primary and secondary hemostatic functionalities of rehydrated, lyophilized platelets
Published in Transfusion (Philadelphia, Pa.) (01-11-2006)“…BACKGROUND: The rehydrated, lyophilized (RL) platelet (PLT) is being developed as a hemostatic infusion agent for the control of active bleeding. The key to…”
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2
Hemostatic properties of glucosamine-based materials
Published in Journal of biomedical materials research. Part A (01-01-2007)“…Glucosamine‐ and N‐acetyl glucosamine‐containing polymers are being used in an increasing number of biomedical applications, including in products for surface…”
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3
Correction of the bleeding time with lyophilized platelet infusions in dogs on cardiopulmonary bypass
Published in Clinical and applied thrombosis/hemostasis (01-01-2008)“…Lyophilized canine platelets were infused in a single large bolus dose into splenectomized dogs after 2 hours' perfusion on cardiopulmonary bypass to test…”
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4
Lyophilized platelets: fifty years in the making
Published in Artificial cells, blood substitutes, and immobilization biotechnology (2007)“…Starting with the work of Klein et al. in the early 1950s, there has been a concerted effort to apply the process of freeze-drying for the preservation of…”
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5
The interaction of factor VIIa with rehydrated, lyophilized platelets
Published in Platelets (Edinburgh) (01-05-2008)“…The experiments presented here were undertaken to determine if factor VIIa (rFVIIa, the Novo Nordisk product NovoSeven™) will directly bind to rehydrated,…”
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6
Aprotinin restores the adhesive capacity of dysfunctional platelets
Published in Thrombosis research (15-02-2003)“…The post-operative coagulopathy associated with cardiopulmonary bypass (CPB) is known to be predominantly related to platelet dysfunction. The use of the…”
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Platelet adhesion testing may predict early hemodialysis arteriovenous graft and fistula failure in end-stage renal disease patients
Published in Clinical and applied thrombosis/hemostasis (01-10-2008)“…Vascular access thrombosis (VAT) is the most morbid and costly complication in end-stage renal disease (ESRD) patients. Although hypercoagulability is a major…”
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8
Flow cytometry of platelets for clinical analysis
Published in Hematology/oncology clinics of North America (01-04-2002)“…Platelets are small, non-homogenous cells with distinctive surface features important to their essential role in hemostasis. The surface membrane is dynamic,…”
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Preservation of Hemostatic and Structural Properties of Rehydrated Lyophilized Platelets: Potential for Long-Term Storage of Dried Platelets for Transfusion
Published in Proceedings of the National Academy of Sciences - PNAS (17-01-1995)“…Currently, therapeutic platelet concentrates can be stored for only 5 days. We have developed a procedure that permits long-term storage of fixed and…”
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10
Evidence that rehydrated, lyophilized red blood cells are sufficiently deformable for normal microcirculation transit
Published in Microscopy research and technique (01-09-2004)“…A method was developed for the preparation of rehydratable lyophilized red blood cells (RL RBCs) that hold promise as cell‐based oxygen carriers for…”
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11
Intracellular function in rehydrated lyophilized platelets
Published in British journal of haematology (01-10-2000)“…This study aimed to evaluate the effect of cross-linking and lyophilization on intracellular signalling processes in rehydrated, lyophilized (RL) platelets,…”
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12
Lyophilized platelets: continued development
Published in Transfusion science (01-02-2000)“…In our initial investigation of functionality of platelets freeze-dried after stabilization with 1.8% paraformaldehyde, we found that the rehydrated cells were…”
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13
In-line leukocyte filtration during bypass. Clinical results from a randomized prospective trial
Published in ASAIO journal (1992) (01-09-1996)“…Leukocyte mediated pulmonary injury may delay recovery after cardiac surgery, and leukocyte depletion during bypass has been suggested. Two groups of patients…”
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Assessment of Platelet Activation by Coronary Sinus Blood Sampling During Balloon Angioplasty and Directional Coronary Atherectomy11This study was supported by the National Heart, Lung, and Blood Institute Specialized Center of Research Grant in Thrombosis (HL26309-15), Bethesda, Maryland
Published in The American journal of cardiology (01-10-1997)Get full text
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44. New developments in lyophilized platelets for arrest of bleeding in transfusion medicine
Published in Cryobiology (01-12-2008)Get full text
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Stabilization of Human Erythrocytes for Lyophilization: Recovery of Biochemical Activities and Membrane Filterability
Published in Blood (16-11-2004)“…It has much more advantages to preserve human red blood cells (RBC) in freezing and drying form than conventional blood storage, even though it is still under…”
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Activation and adherence of lyophilized human platelets on canine vessel strips in the Baumgartner perfusion chamber
Published in The Journal of laboratory and clinical medicine (01-02-1999)“…The Baumgartner perfusion technique was used to test the ability of rehydrated lyophilized human platelets to adhere to the thrombogenic surface of a denuded…”
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Sera From Patients With Heparin-Induced Thrombocytopenia Generate Platelet-Derived Microparticles With Procoagulant Activity: An Explanation for the Thrombotic Complications of Heparin-Induced Thrombocytopenia
Published in Blood (01-12-1994)“…Heparin-induced thrombocytopenia is characterized by moderate thrombocytopenia and thrombotic complications, whereas quinine/quinidine-induced thrombocytopenia…”
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Interaction of Recombinant Factor VIIa with Rehydrated, Lyophilized Platelets
Published in Blood (16-11-2005)“…The experiments presented here were undertaken to determine if factor VIIa (rFVIIa, the Novo Nordisk product NovoSeven™) will directly bind to rehydrated,…”
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20
Effect of INS50589, a Reversible ADP-Receptor Antagonist, on Platelet Function and Blood Loss in a Canine Model of Cardiopulmonary Bypass
Published in Blood (16-11-2005)“…Open-heart surgery performed with cardiopulmonary extracorporeal bypass (CPB) of anticoagulated blood often is complicated by excessive postoperative…”
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