Search Results - "BOCKENSTEDT, Linda K"

Borrelia burgdorferi promotes the establishment of Babesia microti in the northeastern United States by Dunn, Jessica M, Krause, Peter J, Davis, Stephen, Vannier, Edouard G, Fitzpatrick, Meagan C, Rollend, Lindsay, Belperron, Alexia A, States, Sarah L, Stacey, Andrew, Bockenstedt, Linda K, Fish, Durland, Diuk-Wasser, Maria A

“…Babesia microti and Borrelia burgdorferi, the respective causative agents of human babesiosis and Lyme disease, are maintained in their enzootic cycles by the…”
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The impact of nanoparticle ligand density on dendritic-cell targeted vaccines by Bandyopadhyay, Arunima, Fine, Rebecca L, Demento, Stacey, Bockenstedt, Linda K, Fahmy, Tarek M

“…Abstract Dendritic-cell (DC) targeted antigen delivery systems hold promise for enhancing vaccine efficacy and delivery of therapeutics. However, it is not…”
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The RpoS Gatekeeper in Borrelia burgdorferi : An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity by Caimano, Melissa J, Groshong, Ashley M, Belperron, Alexia, Mao, Jialing, Hawley, Kelly L, Luthra, Amit, Graham, Danielle E, Earnhart, Christopher G, Marconi, Richard T, Bockenstedt, Linda K, Blevins, Jon S, Radolf, Justin D

“…Maintenance of within its enzootic cycle requires a complex regulatory pathway involving the alternative σ factors RpoN and RpoS and two ancillary -acting…”
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Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone by Lawres, Lauren A, Garg, Aprajita, Kumar, Vidya, Bruzual, Igor, Forquer, Isaac P, Renard, Isaline, Virji, Azan Z, Boulard, Pierre, Rodriguez, Eduardo X, Allen, Alexander J, Pou, Sovitj, Wegmann, Keith W, Winter, Rolf W, Nilsen, Aaron, Mao, Jialing, Preston, Douglas A, Belperron, Alexia A, Bockenstedt, Linda K, Hinrichs, David J, Riscoe, Michael K, Doggett, J Stone, Ben Mamoun, Choukri

“…Human babesiosis is a tick-borne multisystem disease caused by Babesia species of the apicomplexan phylum. Most clinical cases and fatalities of babesiosis are…”
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Circulating fibrocytes: collagen-secreting cells of the peripheral blood by Quan, Timothy E, Cowper, Shawn, Wu, Sou-Pan, Bockenstedt, Linda K, Bucala, Richard

“…Since the original description of circulating fibrocytes in 1994, our knowledge of this unique cell population has grown steadily. While initially described in…”
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heterogeneous motility of the Lyme disease spirochete in gelatin mimics dissemination through tissue by Harman, Michael W, Dunham-Ems, Star M, Caimano, Melissa J, Belperron, Alexia A, Bockenstedt, Linda K, Fu, Henry C, Radolf, Justin D, Wolgemuth, Charles W

“…The Lyme disease spirochete Borrelia burgdorferi exists in nature in an enzootic cycle that involves the arthropod vector Ixodes scapularis and mammalian…”
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Longitudinal serum proteomics analyses identify unique and overlapping host response pathways in Lyme disease and West Nile virus infection by Boada, Patrick, Fatou, Benoit, Belperron, Alexia A, Sigdel, Tara K, Smolen, Kinga K, Wurie, Zainab, Levy, Ofer, Ronca, Shannon E, Murray, Kristy O, Liberto, Juliane M, Rashmi, Priyanka, Kerwin, Maggie, Montgomery, Ruth R, Bockenstedt, Linda K, Steen, Hanno, Sarwal, Minnie M

“…Advancement in proteomics methods for interrogating biological samples has helped identify disease biomarkers for early diagnostics and unravel underlying…”
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Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging by Qian, Feng, Guo, Xiuyang, Wang, Xiaomei, Yuan, Xiaoling, Chen, Shu, Malawista, Stephen E, Bockenstedt, Linda K, Allore, Heather G, Montgomery, Ruth R

“…Aging is associated with a progressive decline in immune function (immunosenescence) resulting in an increased susceptibility to viral and bacterial…”
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Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells by Jiang, Ruoyi, Meng, Hailong, Raddassi, Khadir, Fleming, Ira, Hoehn, Kenneth B, Dardick, Kenneth R, Belperron, Alexia A, Montgomery, Ruth R, Shalek, Alex K, Hafler, David A, Kleinstein, Steven H, Bockenstedt, Linda K

“…The skin lesion erythema migrans (EM) is an initial sign of the Ixodes tick-transmitted Borreliella spirochetal infection known as Lyme disease. T cells and…”
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Myeloid Differentiation Antigen 88 Deficiency Impairs Pathogen Clearance but Does Not Alter Inflammation in Borrelia burgdorferi-Infected Mice by LIU, Nengyin, MONTGOMERY, Ruth R, BARTHOLD, Stephen W, BOCKENSTEDT, Linda K

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Insights From Omics in Lyme Disease by Bockenstedt, Linda K, Belperron, Alexia A

“…Abstract Lyme disease is a zoonotic infection due to Ixodes tick–transmitted Borrelia burgdorferi sensu lato spirochetes and the most common vector-borne…”
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MyD88 deficiency markedly worsens tissue inflammation and bacterial clearance in mice infected with Treponema pallidum, the agent of syphilis by Silver, Adam C, Dunne, Dana W, Zeiss, Caroline J, Bockenstedt, Linda K, Radolf, Justin D, Salazar, Juan C, Fikrig, Erol

“…Research on syphilis, a sexually transmitted infection caused by the non-cultivatable spirochete Treponema pallidum, has been hampered by the lack of an inbred…”
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Marginal Zone B-Cell Depletion Impairs Murine Host Defense against Borrelia burgdorferi Infection by Belperron, Alexia A, Dailey, Catherine M, Booth, Carmen J, Bockenstedt, Linda K

“…Marginal zone B (MZB) cells are a B-cell subset that produces T-cell-independent antibodies to blood-borne antigens. In this study, we examined the effects of…”
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Langerhans Cell Deficiency Impairs Ixodes scapularis Suppression of Th1 Responses in Mice by Vesely, Diana L, Fish, Durland, Shlomchik, Mark J, Kaplan, Daniel H, Bockenstedt, Linda K

“…Ixodes scapularis ticks transmit a number of human pathogens, including the Lyme disease spirochete Borrelia burgdorferi. I. scapularis suppresses host…”
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Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis by Jutras, Brandon L., Lochhead, Robert B., Kloos, Zachary A., Biboy, Jacob, Strle, Klemen, Booth, Carmen J., Govers, Sander K., Gray, Joe, Schumann, Peter, Vollmer, Waldemar, Bockenstedt, Linda K., Steere, Allen C., Jacobs-Wagner, Christine

“…Lyme disease is a multisystem disorder caused by the spirochete Borrelia burgdorferi. A common late-stage complication of this disease is oligoarticular…”
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Caspase 1 Inflammasome Is Not Required for Control of Murine Lyme Borreliosis by Liu, Nengyin, Belperron, Alexia A, Booth, Carmen J, Bockenstedt, Linda K

“…The contribution of the inflammasome to the development of immune responses and disease during infection with the Lyme disease spirochete, Borrelia…”
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Immune Response to Borrelia : Lessons from Lyme Disease Spirochetes by Bockenstedt, Linda K, Wooten, R Mark, Baumgarth, Nicole

“…The mammalian host responds to infection with spirochetes through a highly orchestrated immune defense involving innate and adaptive effector functions aimed…”
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Cutting Edge: CD1d Deficiency Impairs Murine Host Defense Against the Spirochete, Borrelia burgdorferi by Kumar, Hemant, Belperron, Alexia, Barthold, Stephen W, Bockenstedt, Linda K

“…CD1 molecules can present microbial lipid Ag to T cells, suggesting that they participate in host defense against pathogens. In this study, we examined the…”
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Spirochete antigens persist near cartilage after murine Lyme borreliosis therapy by Bockenstedt, Linda K, Gonzalez, David G, Haberman, Ann M, Belperron, Alexia A

“…An enigmatic feature of Lyme disease is the slow resolution of musculoskeletal symptoms that can continue after treatment, with some patients developing an…”
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Detection of Attenuated, Noninfectious Spirochetes in Borrelia burgdorferi–Infected Mice after Antibiotic Treatment by Bockenstedt, Linda K., Mao, Jialing, Hodzic, Emir, Barthold, Stephen W., Fish, Durland

“…Xenodiagnosis by ticks was used to determine whether spirochetes persist in mice after 1 month of antibiotic therapy for vectorborne Borrelia burgdorferi…”
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