Search Results - "BOCHOT, A"

Intraocular implants for extended drug delivery: Therapeutic applications by Bourges, J.L., Bloquel, C., Thomas, A., Froussart, F., Bochot, A., Azan, F., Gurny, R., BenEzra, D., Behar-Cohen, F.

“…An overview of ocular implants with therapeutic application potentials is provided. Various types of implants can be used as slow release devices delivering…”
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Oil-cyclodextrin based beads for oral delivery of poorly-soluble drugs by Hamoudi, M C, Bochot, A

“…The main interest of cyclodextrins results from their ability to form inclusion complexes with hydrophobic molecules. This property is employed in…”
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Beads made of cyclodextrin and oil for the oral delivery of lipophilic drugs: In vitro studies in simulated gastro-intestinal fluids by Hamoudi, M., Fattal, E., Gueutin, C., Nicolas, V., Bochot, A.

“…The aim of this work was to investigate the stability in vitro, in simulated gastro-intestinal fluids, of beads, made of α-cyclodextrin and soybean oil, and to…”
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Formulations based on alpha cyclodextrin and soybean oil: an approach to modulate the oral release of lipophilic drugs by Hamoudi, M.C., Bourasset, F., Domergue-Dupont, V., Gueutin, C., Nicolas, V., Fattal, E., Bochot, A.

“…The purpose of this work was to investigate the potential of α-cyclodextrin combined to soybean oil-based formulations to modulate the release of a model drug,…”
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Liposomal amphotericin B eye drops to treat fungal keratitis: Physico-chemical and formulation stability by Morand, K., Bartoletti, A.C., Bochot, A., Barratt, G., Brandely, M.L., Chast, F.

“…Local fungal infections with Candida, Fusarium, Curvularia and Aspergillus can lead to serious ulceration of the cornea and must be treated rapidly. The…”
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Cationic nanoemulsion as a delivery system for oligonucleotides targeting malarial topoisomerase II by Bruxel, F., Cojean, S., Bochot, A., Teixeira, H., Bories, C., Loiseau, P.-M., Fattal, E.

“…A promising strategy based on the antisense oligonucleotides against the Plasmodium falciparum topoisomerase II has been considered using cationic nanoemulsion…”
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Design of poly-ε-caprolactone nanospheres coated with bioadhesive hyaluronic acid for ocular delivery by Barbault-Foucher, S, Gref, R, Russo, P, Guechot, J, Bochot, A

“…This study was performed to design a new ocular drug delivery system based on poly-ε-caprolactone (PCL) biodegradable nanospheres (NS) coated with a…”
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Beads made of α-cyclodextrin and soybean oil: the drying method influences bead properties and drug release by Hamoudi, M. C., Saunier, J., Gueutin, C., Fattal, E., Bochot, A.

“…Freeze-dried beads made of α-cyclodextrin and soybean oil were reported previously as an efficient system for the oral delivery of lipophilic drugs. In the…”
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α-Cyclodextrin/oil beads: An innovative self-assembling system by Bochot, A., Trichard, L., Le Bas, G., Alphandary, H., Grossiord, J.L., Duchêne, D., Fattal, E.

“…The aim of this work was to characterise a new type of particulate system, named beads, prepared by a straightforward technique starting from a mixture of…”
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Gel and solid matrix systems for the controlled delivery of drug carrier-associated nucleic acids by Fattal, E, De Rosa, G, Bochot, A

“…In order to achieve a sustained pharmacological activity of oligonucleotides (ODNs) and avoid repeated administrations, we have developed a new concept of…”
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Formulation and characterisation of beads prepared from natural cyclodextrins and vegetable, mineral or synthetic oils by Trichard, L., Fattal, E., Le Bas, G., Duchêne, D., Grossiord, J.-L., Bochot, A.

“…A continuous external shaking for 2.5 days of a mixture composed of α-cyclodextrin (6%), soybean oil (19.6%) and water (74.4%) resulted in a calibrated lipid…”
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Intravitreal Delivery of Oligonucleotides by Sterically Stabilized Liposomes by Bochot, Amelie, Fattal, Elias, Boutet, Valerie, Deverre, Jean Robert, Jeanny, Jean Claude, Chacun, Helene, Couvreur, Patrick

“…The efficacy of sterically stabilized liposomes for delivering a model phosphodiester oligonucleotide intravitreally was investigated in the rabbit. Ocular…”
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Ocular and systemic bio-distribution of rhodamine-conjugated liposomes loaded with VIP injected into the vitreous of Lewis rats by Camelo, S, Lajavardi, L, Bochot, A, Goldenberg, B, Naud, M C, Fattal, E, Behar-Cohen, F, de Kozak, Y

“…Local delivery of therapeutic molecules encapsulated within liposomes is a promising method to treat ocular inflammation. The purpose of the present study was…”
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Drainage of fluorescent liposomes from the vitreous to cervical lymph nodes via conjunctival lymphatics by Camelo, S, Lajavardi, L, Bochot, A, Goldenberg, B, Naud, M C, Fattal, E, Behar-Cohen, F, de Kozak, Y

“…The use of liposomes as carriers for the delivery of biologically active molecules into the eye is of major interest. Indeed, encapsulation of biologically…”
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Beads made of alpha-cyclodextrin and vegetable oils: oil composition and physicochemical properties influence bead feasibility and properties by Trichard, L., Chaminade, P., Grossiord, J.-L., Le Bas, G., Huang, N., Durand, D., Fattal, E., Bochot, A.

“…Beads made of alpha-cyclodextrin and soybean oil are an efficient system for the encapsulation of lipophilic drugs. In this work we investigated the impact of…”
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Intraocular delivery of oligonucleotides by Gomes Dos Santos, A L, Bochot, A, Fattal, E

“…Anti-mRNA and particularly antisense oligonucleotides are molecules able to inhibit gene expression after intracellular penetration being potentially very…”
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Properties of various thermoassociating polymers: pharmaceutical and cosmetic applications by Agnely, F., Djedour, A., Bochot, A., Grossiord, J.-L.

“…This paper describes the main results obtained in our group on three thermoassociating polymers with interesting applications in the pharmaceutical and…”
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Drug delivery systems for intraocular applications by Bourges, J-L, Touchard, E, Kowalczuk, L, Berdugo, M, Thomas-Doyle, A, Bochot, A, Gomez, A, Azan, F, Gurny, R, Behar-Cohen, F

“…Numerous drug delivery systems (DDSs) can be used as intraocular tools to provide a sustained and calibrated release for a specific drug. Great progress has…”
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Comparison of the Ocular Distribution of a Model Oligonucleotide after Topical Instillation in Rabbits of Conventional and New Dosage Forms by Bochota, A., Mashhour, B., Puisieux, F., Couvreur, P., Fattal, E.

“…Abstract The distribution of a model 16-mer oligothymidylate (pdT16) in several ocular tissues (cornea, conjunctiva, sclera, iris, lens, aqueous and vitreous…”
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Exosomes/EVs: EXTRACELLULAR VESICLES FROM HUC-MSC DELIVERED BY AN INJECTABLE BIOMATERIAL AS A CARDIO-REPARATIVE THERAPY IN A RAT MODEL OF MYOCARDIAL ISCHEMIA-REPERFUSION by Pezzana, C., Guesdon, R., Cras, A., Correa, B. Lima, Desgres, M., Alberdi, A., Pidial, L., Guillas, C., Hagège, A., Simelière, F., Bochot, A., Agnely, F., Menasché, P.

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