Search Results - "BOCCA, Anamélia Lorenzetti"
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NLRP3 inflammasome activation by Paracoccidioides brasiliensis
Published in PLoS neglected tropical diseases (01-12-2013)“…Paracoccidioides brasiliensis is the etiologic agent of paracoccidioidomycosis (PCM), the most prevalent systemic mycosis that is geographically confined to…”
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Complete Genome Sequence of Mycobacterium massiliense
Published in Journal of Bacteriology (01-10-2012)“…Mycobacterium massiliense is a rapidly growing bacterium associated with opportunistic infections. The genome of a representative isolate (strain GO 06)…”
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Expanding the Toolbox for Functional Genomics in Fonsecaea pedrosoi : The Use of Split-Marker and Biolistic Transformation for Inactivation of Tryptophan Synthase ( trpB ) Gene
Published in Journal of fungi (Basel) (08-02-2023)“…Chromoblastomycosis (CBM) is a disease caused by several dematiaceous fungi from different genera, and is the most common which has been clinically isolated…”
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Photodynamic therapy leads to complete remission of tongue tumors and inhibits metastases to regional lymph nodes
Published in Journal of biomedical nanotechnology (01-05-2013)“…In patients diagnosed with oral cancer, the most important prognostic indicator for patient survival after primary treatment is metastasis to the cervical…”
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Oropharynx HPV status and its relation to HIV infection
Published in PeerJ (San Francisco, CA) (22-03-2018)“…The number of oropharyngeal lesions caused by HPV (Human papillomavirus) has been increasing worldwide in the past years. In spite of the clinical relevance of…”
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Dopamine-loaded nanoparticle systems circumvent the blood–brain barrier restoring motor function in mouse model for Parkinson’s Disease
Published in Scientific reports (26-07-2021)“…Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease of the central nervous system. Early treatment for PD is efficient; however,…”
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Effects of metoclopramide on the expression of metalloproteinases and interleukins in left colonic anastomoses. An experimental study
Published in Acta cirurgica brasileira (01-11-2015)“…To evaluate the effects of metoclopramide on metalloproteinases (MMP) and interleukins (IL) gene expression in colonic anastomoses in rats. Eighty rats were…”
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In silico construction of a multiepitope Zika virus vaccine using immunoinformatics tools
Published in Scientific reports (07-01-2022)“…Zika virus (ZIKV) is an arbovirus from the Flaviviridae family and Flavivirus genus. Neurological events have been associated with ZIKV-infected individuals,…”
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Kicking sleepers out of bed: Macrophages promote reactivation of dormant Cryptococcus neoformans by extracellular vesicle release and non-lytic exocytosis
Published in PLoS pathogens (30-11-2023)“…Macrophages play a key role in disseminated cryptococcosis, a deadly fungal disease caused by Cryptococcus neoformans. This opportunistic infection can arise…”
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Erg6 affects membrane composition and virulence of the human fungal pathogen Cryptococcus neoformans
Published in Fungal genetics and biology (01-07-2020)“…•Erg6 is required for Cryptococcus neoformans high temperature growth.•ERG6 deletion impairs susceptibility to stress and antifungal agents.•Sterol membrane…”
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Turning Up the Heat: Inflammasome Activation by Fungal Pathogens
Published in PLoS pathogens (01-07-2015)“… [...]microbiota differences are observed in inflammasome knockout mice [36], resulting in microbiota-driven differences in phenotypes (i.e., microbiota would…”
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Distinct anti-NP, anti-RBD and anti-Spike antibody profiles discriminate death from survival in COVID-19
Published in Frontiers in immunology (09-10-2023)“…IntroductionInfection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces rapid production of IgM, IgA, and IgG antibodies directed to…”
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The Effects of Paracoccidioides brasiliensis Infection on GM-CSF- and M-CSF-Induced Mouse Bone Marrow-Derived Macrophage from Resistant and Susceptible Mice Strains
Published in Mediators of Inflammation (01-01-2015)“…Considering the importance of macrophages as the first line of defense against fungal infection and the different roles played by the two M1- and M2-like…”
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Antifungal Activity of Amphotericin B Conjugated to Nanosized Magnetite in the Treatment of Paracoccidioidomycosis
Published in PLoS neglected tropical diseases (15-06-2016)“…This study reports on in vitro and in vivo tests that sought to assess the antifungal activity of a newly developed magnetic carrier system comprising…”
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Fish Oil Nanoemulsion Supplementation Attenuates Bleomycin-Induced Pulmonary Fibrosis BALB/c Mice
Published in Nanomaterials (Basel, Switzerland) (14-05-2022)“…Diets rich in omega-3 or -6 fatty acids will produce different profiles for cell membranes phospholipid constitutions. Omegas 3 and 6 are part of the diet and…”
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Engineered Fluorescent Strains of Cryptococcus neoformans: a Versatile Toolbox for Studies of Host-Pathogen Interactions and Fungal Biology, Including the Viable but Nonculturable State
Published in Microbiology spectrum (26-10-2022)“…Cryptococcus neoformans is an opportunistic fungal pathogen known for its remarkable ability to infect and subvert phagocytes. This ability provides survival…”
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The Major Chromoblastomycosis Etiologic Agent Fonsecaea pedrosoi Activates the NLRP3 Inflammasome
Published in Frontiers in immunology (20-11-2017)“…is the main etiologic agent of chromoblastomycosis (CBM), one of the most prevalent subcutaneous mycosis in tropical and subtropical countries. CBM is a poorly…”
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Antifungal drugs: New insights in research & development
Published in Pharmacology & therapeutics (Oxford) (01-03-2019)“…The need for better antifungal therapy is commonly accepted in view of the high mortality rates associated with systemic infections, the low number of…”
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Intracellular Eukaryotic Pathogens' Virulence Attributes and Their Interplay with Host Immune Defenses
Published in Mediators of Inflammation (01-01-2017)“…Anamélia Lorenzetti Bocca [1] and Célia Maria de Almeida Soares [2] and Joshua D. Nosanchuk [3] and Ildinete Silva-Pereira [4] 1, Cell Biology Department of…”
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Transcriptional Remodeling Patterns in Murine Dendritic Cells Infected with Paracoccidioides brasiliensis: More Is Not Necessarily Better
Published in Journal of fungi (Basel) (24-11-2020)“…Most people infected with the fungus Paracoccidioides spp. do not get sick, but approximately 5% develop paracoccidioidomycosis. Understanding how host…”
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