Search Results - "BO SAN PAUL LAI"

A selective HDAC8 inhibitor potentiates antitumor immunity and efficacy of immune checkpoint blockade in hepatocellular carcinoma by Yang, Weiqin, Feng, Yu, Zhou, Jingying, Cheung, Otto Ka-Wing, Cao, Jianquan, Wang, Jing, Tang, Wenshu, Tu, Yalin, Xu, Liangliang, Wu, Feng, Tan, Zhiwu, Sun, Hanyong, Tian, Yuan, Wong, John, Lai, Paul Bo-San, Chan, Stephen Lam, Chan, Anthony Wing-Hung, Tan, Patrick Boon-Ooi, Chen, Zhiwei, Sung, Joseph Jao-Yiu, Yip, Kevin Yuk-Lap, To, Ka-Fai, Cheng, Alfred Sze-Lok

“…Insufficient T cell infiltration into noninflamed tumors, such as hepatocellular carcinoma (HCC), restricts the effectiveness of immune-checkpoint blockade…”
Get more information

Liver stiffness measurement predicts high-grade post-hepatectomy liver failure: A prospective cohort study by Chong, Charing Ching-Ning, Wong, Grace Lai-Hung, Chan, Anthony Wing-Hung, Wong, Vincent Wai-Sun, Fong, Anthony Kwong-Wai, Cheung, Yue-Sun, Wong, John, Lee, Kit-Fai, Chan, Stephen L, Lai, Paul Bo-San, Chan, Henry Lik-Yuen

“…Liver stiffness measurement using transient elastography appears to be an excellent tool for detection of liver fibrosis and cirrhosis with high accuracy. The…”
Get full text

O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress by Xu, Weiqi, Zhang, Xiang, Wu, Jian-lin, Fu, Li, Liu, Ken, Liu, Dabin, Chen, George Gong, Lai, Paul Bo-san, Wong, Nathalie, Yu, Jun

“…Graphical abstract…”
Get full text

Long-term outcomes of microwave versus radiofrequency ablation for hepatocellular carcinoma by surgical approach: A retrospective comparative study by Lee, Kit-fai, Wong, John, Hui, Joyce Wai-yi, Cheung, Yue-sun, Chong, Charing Ching-ning, Fong, Anthony Kong-wai, Yu, Simon Chun-ho, Lai, Paul Bo-san

“…Summary Background Both microwave ablation (MWA) and radiofrequency ablation (RFA) are commonly employed local ablation techniques for malignant liver tumors…”
Get full text

Determining the surgical quality improvement model by outcome monitoring in Hong Kong public hospitals by Cheung, Yue‐Sun, Fung, Anthony Shu‐Yan, Lai, Paul Bo‐San

“…Aim Reduction in the surgical mortality has been observed in Hong Kong public hospitals after the implementation of the Surgical Outcomes Monitoring and…”
Get full text

The ATP-binding cassette transporter ABCF1 is a hepatic oncofetal protein that promotes chemoresistance, EMT and cancer stemness in hepatocellular carcinoma by Fung, Sze Wai, Cheung, Phyllis Fung-Yi, Yip, Chi Wai, Ng, Linda Wing-Chi, Cheung, Tan To, Chong, Charing Ching-Ning, Lee, Carol, Lai, Paul Bo-San, Chan, Anthony Wing-Hung, Tsao, George Sai-Wah, Wong, Chi-Hang, Chan, Stephen Lam, Lo, Kwok Wai, Cheung, Siu Tim

“…ATP-binding cassette (ABC) transporters mediate multidrug resistance and cancer stem cell properties in various model systems. Yet, their biological…”
Get full text

Superior mesenteric venous thrombophlebitis: A rare complication of a common disease by Wong, Leo Chun‐Hei, Lee, Kit‐Fai, Lai, Paul Bo‐San, Chong, Charing Ching‐Ning

“…We would like to report a case of acute appendicitis complicated with superior mesenteric venous (SMV) thrombophlebitis. A 61‐year‐old gentleman presented with…”
Get full text

A comparability study of immunohistochemical assays for PD-L1 expression in hepatocellular carcinoma by Shi, Lei, Zhang, Shu-Jun, Chen, Jun, Lu, Shi-Xun, Fan, Xin-Juan, Tong, Joanna Hung-Man, Chow, Chit, Tin, Edith Ka-Yee, Chan, Stephen Lam, Chong, Charing Ching-Ning, Lai, Paul Bo-San, To, Ka-Fai, Wong, Nathalie, Chan, Anthony Wing-Hung

“…Programmed death ligand 1 (PD-L1) protein expression by immunohistochemistry is a promising biomarker for PD-1/PD-L1 blockade in hepatocellular carcinoma…”
Get full text

One‐stop clinic for ketamine‐associated uropathy: report on service delivery model, patients' characteristics and non‐invasive investigations at baseline by a cross‐sectional study in a prospective cohort of 318 teenagers and young adults by Tam, Yuk‐Him, Ng, Chi‐Fai, Pang, Kristine Kit‐Yi, Yee, Chi‐Hang, Chu, Winnie Chiu‐Wing, Leung, Vivian Yee‐Fong, Wong, Grace Lai‐Hung, Wong, Vincent Wai‐Sun, Chan, Henry Lik‐Yuen, Lai, Paul Bo‐San

“…Objective To describe a service delivery model and report the baseline characteristics of patients investigated by a non‐invasive approach for…”
Get full text

Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development by Yip, Wing-Kit, Cheng, Alfred Sze-Lok, Zhu, Ranxu, Lung, Raymond Wai-Ming, Tsang, Daisy Pui-Fong, Lau, Suki Shuk-Kei, Chen, Yangchao, Sung, Jonathan Gabriel, Lai, Paul Bo-San, Ng, Enders Kai-On, Yu, Jun, Wong, Nathalie, To, Ka-Fai, Wong, Vincent Wai-Sun, Sung, Joseph Jao-Yiu, Chan, Henry Lik-Yuen

“…The biological pathways and functional properties by which misexpressed microRNAs (miRNAs) contribute to liver carcinogenesis have been intensively…”
Get full text

Spontaneous liver rupture in hypereosinophilic syndrome： A rare but fatal complication by Cheung, Yue-Sun, Wong, Shun, Lam, Philip Koon-Ngai, Lee, Kit-Fai, Wong, John, Lai, Paul Bo-San

“…We report a rare case of spontaneous liver rupture in a patient with hypereosinophilic syndrome （HES）, of which the diagnosis was delayed, resulting in a fatal…”
Get full text

Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis by Zhou, Jingying, Wang, Huanyu, Shu, Ting, Wang, Jing, Yang, Weiqin, Li, Jingqing, Ding, Lipeng, Liu, Man, Sun, Hanyong, Wong, John, Lai, Paul Bo-san, Tsang, Shun-Wa, Ward, Simon E., Chow, King-Lau, Sung, Joseph Jao-yiu, Sze-Lok Cheng, Alfred

“…Massive expansion of immature and suppressive myeloid cells is a common feature of malignant solid tumors. Over-expression of cyclin-dependent kinase 20, also…”
Get full text

Transcriptional regulation of the tumor suppressor FHL2 by p53 in human kidney and liver cells by Xu, Jiaying, Zhou, Junwei, Li, Man-Shan, Ng, Chor-Fung, Ng, Yuen-Keng, Lai, Paul Bo-San, Tsui, Stephen Kwok-Wing

“…Four and a Half LIM protein 2 (FHL2) is a LIM domain only protein that is able to form various protein complexes and regulate gene transcription. Recent…”
Get full text

Albumin-bilirubin grade predicts the outcomes of liver resection versus radiofrequency ablation for very early/early stage of hepatocellular carcinoma by Chong, Charing Ching-Ning, Chan, Anthony Wing-Hung, Wong, John, Chu, Cheuk-Man, Chan, Stephen Lam, Lee, Kit-Fai, Yu, Simon Chun-Ho, To, Ka-Fai, Johnson, Philip, Lai, Paul Bo-San

“…Whether liver resection or ablation should be the first-line treatment for very early/early hepatocellular carcinoma (HCC) in patients who are candidates for…”
Get full text

Surveillance programme for hepatocellular carcinoma improves the survival of patients with chronic viral hepatitis by Wong, Grace Lai-Hung, Wong, Vincent Wai-Sun, Tan, Guang-Ming, Ip, Ka-Ian, Lai, Wing-Kwan, Li, Yuk-Wah, Mak, Mercedes Shun-Chi, Lai, Paul Bo-San, Sung, Joseph Jao-Yiu, Chan, Henry Lik-Yuen

“…Background: The survival benefit of surveillance for hepatocellular carcinoma (HCC) is controversial. Aim: We aimed to examine the survival benefit of HCC…”
Get full text

Novel biomarkers GEP/ABCB5 regulate response to adjuvant transarterial chemoembolization after curative hepatectomy for hepatocellular carcinoma by Chong, Charing Ching-Ning, Cheung, Siu Tim, Cheung, Yue-Sun, Chan, Anthony Wing-Hung, Chan, Stephen Lam, Yu, Simon Chun-Ho, Lai, Paul Bo-San

“…Transarterial chemoembolization (TACE) is the most commonly used adjuvant therapy for hepatocellular carcinoma (HCC) after curative resection. Responses to…”
Get full text

Impact of antiviral therapy on post-hepatectomy outcome for hepatitis B-related hepatocellular carcinoma by Chong, Charing Ching Ning, Wong, Grace Lai Hung, Lai, Paul Bo San

“…The outcome after curative resection for hepatocellular carcinoma(HCC)remains unsatisfactory due to the high recurrence rate after surgery.In patients with…”
Get full text

Percutaneous radiofrequency ablation versus surgical radiofrequency ablation for malignant liver tumours: the long‐term results by Wong, John, Lee, Kit‐Fai, Yu, Simon Chun‐Ho, Lee, Paul Sing‐Fun, Cheung, Yue‐Sun, Chong, Ching‐Ning, Ip, Philip Ching‐Tak, Lai, Paul Bo‐San

“…Abstract Background Radiofrequency ablation (RFA) has been used to treat hepatocellular carcinoma (HCC) and liver metastases for more than 10 years with…”
Get full text

Epstein‐Barr virus positive inflammatory pseudotumours (IPT) and IPT‐like tumours by Cheung, Alyson, Leung, Howard Ho‐Wai, Lee, Kit‐Fai, Lai, Paul Bo‐San, Chong, Charing Ching‐Ning

“…Inflammatory pseudotumour (IPT) is a spectrum of lesions which mimic malignancies in various organs. Preoperative diagnosis is often challenging. In this case…”
Get full text

Differential functions of C- and N-terminal hepatitis B x protein in liver cells treated with doxorubicin in normoxic or hypoxic condition by Chau, Davor Kin-Fan, Chen, George Gong, Zhang, Haitao, Leung, Billy Cheuk Sing, Chun, Sukying, Lai, Paul Bo-San

“…Hepatitis viral B x protein (HBx), a hepatocarcinogen, is frequently mutated. Hypoxia influences the growth of HCC and also the sensitivity of tumor cells to…”
Get full text