Search Results - "BMC medicine"

Key challenges for delivering clinical impact with artificial intelligence by Kelly, Christopher J, Karthikesalingam, Alan, Suleyman, Mustafa, Corrado, Greg, King, Dominic

“…Artificial intelligence (AI) research in healthcare is accelerating rapidly, with potential applications being demonstrated across various domains of medicine…”
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Calibration: the Achilles heel of predictive analytics by Van Calster, Ben, McLernon, David J, van Smeden, Maarten, Wynants, Laure, Steyerberg, Ewout W

“…The assessment of calibration performance of risk prediction models based on regression or more flexible machine learning algorithms receives little attention…”
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The epidemiological burden of obesity in childhood: a worldwide epidemic requiring urgent action by Di Cesare, Mariachiara, Sorić, Maroje, Bovet, Pascal, Miranda, J Jaime, Bhutta, Zulfiqar, Stevens, Gretchen A, Laxmaiah, Avula, Kengne, Andre-Pascal, Bentham, James

“…In recent decades, the prevalence of obesity in children has increased dramatically. This worldwide epidemic has important consequences, including psychiatric,…”
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Quantifying the impact of physical distance measures on the transmission of COVID-19 in the UK by Jarvis, Christopher I, Van Zandvoort, Kevin, Gimma, Amy, Prem, Kiesha, Klepac, Petra, Rubin, G James, Edmunds, W John

“…To mitigate and slow the spread of COVID-19, many countries have adopted unprecedented physical distancing policies, including the UK. We evaluate whether…”
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The Health Stigma and Discrimination Framework: a global, crosscutting framework to inform research, intervention development, and policy on health-related stigmas by Stangl, Anne L, Earnshaw, Valerie A, Logie, Carmen H, van Brakel, Wim, C Simbayi, Leickness, Barré, Iman, Dovidio, John F

“…Stigma is a well-documented barrier to health seeking behavior, engagement in care and adherence to treatment across a range of health conditions globally. In…”
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Celiac disease: a comprehensive current review by Caio, Giacomo, Volta, Umberto, Sapone, Anna, Leffler, Daniel A, De Giorgio, Roberto, Catassi, Carlo, Fasano, Alessio

“…Celiac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and possible…”
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Association between gut microbiota and preeclampsia-eclampsia: a two-sample Mendelian randomization study by Li, Pengsheng, Wang, Haiyan, Guo, Lan, Gou, Xiaoyan, Chen, Gengdong, Lin, Dongxin, Fan, Dazhi, Guo, Xiaoling, Liu, Zhengping

“…Abstract Background Several recent observational studies have reported that gut microbiota composition is associated with preeclampsia. However, the causal…”
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COVID-19 length of hospital stay: a systematic review and data synthesis by Rees, Eleanor M, Nightingale, Emily S, Jafari, Yalda, Waterlow, Naomi R, Clifford, Samuel, B Pearson, Carl A, Group, Cmmid Working, Jombart, Thibaut, Procter, Simon R, Knight, Gwenan M

“…The COVID-19 pandemic has placed an unprecedented strain on health systems, with rapidly increasing demand for healthcare in hospitals and intensive care units…”
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Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies by Cupp, Meghan A, Cariolou, Margarita, Tzoulaki, Ioanna, Aune, Dagfinn, Evangelou, Evangelos, Berlanga-Taylor, Antonio J

“…Although neutrophils have been linked to the progression of cancer, uncertainty exists around their association with cancer outcomes, depending on the site,…”
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Stigma in health facilities: why it matters and how we can change it by Nyblade, Laura, Stockton, Melissa A, Giger, Kayla, Bond, Virginia, Ekstrand, Maria L, Lean, Roger Mc, Mitchell, Ellen M H, Nelson, La Ron E, Sapag, Jaime C, Siraprapasiri, Taweesap, Turan, Janet, Wouters, Edwin

“…Stigma in health facilities undermines diagnosis, treatment, and successful health outcomes. Addressing stigma is fundamental to delivering quality healthcare…”
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The impact of non-pharmaceutical interventions on SARS-CoV-2 transmission across 130 countries and territories by Liu, Yang, Morgenstern, Christian, Kelly, James, Lowe, Rachel, Jit, Mark

“…Non-pharmaceutical interventions (NPIs) are used to reduce transmission of SARS coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19)…”
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New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis by Hou, Yuan, Zhao, Junfei, Martin, William, Kallianpur, Asha, Chung, Mina K, Jehi, Lara, Sharifi, Nima, Erzurum, Serpil, Eng, Charis, Cheng, Feixiong

“…Coronavirus Disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now been confirmed worldwide. Yet,…”
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Ethnic and socioeconomic differences in SARS-CoV-2 infection: prospective cohort study using UK Biobank by Niedzwiedz, Claire L, O'Donnell, Catherine A, Jani, Bhautesh Dinesh, Demou, Evangelia, Ho, Frederick K, Celis-Morales, Carlos, Nicholl, Barbara I, Mair, Frances S, Welsh, Paul, Sattar, Naveed, Pell, Jill P, Katikireddi, S Vittal

“…Understanding of the role of ethnicity and socioeconomic position in the risk of developing SARS-CoV-2 infection is limited. We investigated this in the UK…”
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Studying complexity in health services research: desperately seeking an overdue paradigm shift by Greenhalgh, Trisha, Papoutsi, Chrysanthi

“…Complexity is much talked about but sub-optimally studied in health services research. Although the significance of the complex system as an analytic lens is…”
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Coronavirus: the spread of misinformation by Mian, Areeb, Khan, Shujhat

“…Keywords: COVID-19, Coronavirus, Misinformation, Internet, Antiscience, Pandemic, Public health…”
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Mechanisms linking childhood trauma exposure and psychopathology: a transdiagnostic model of risk and resilience by McLaughlin, Katie A, Colich, Natalie L, Rodman, Alexandra M, Weissman, David G

“…Transdiagnostic processes confer risk for multiple types of psychopathology and explain the co-occurrence of different disorders. For this reason,…”
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Impact of lockdown on COVID-19 epidemic in Île-de-France and possible exit strategies by Di Domenico, Laura, Pullano, Giulia, Sabbatini, Chiara E, Boëlle, Pierre-Yves, Colizza, Vittoria

“…More than half of the global population is under strict forms of social distancing. Estimating the expected impact of lockdown and exit strategies is critical…”
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Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017 by Avan, Abolfazl, Digaleh, Hadi, Di Napoli, Mario, Stranges, Saverio, Behrouz, Reza, Shojaeianbabaei, Golnaz, Amiri, Amin, Tabrizi, Reza, Mokhber, Naghmeh, Spence, J David, Azarpazhooh, Mahmoud Reza

“…Socioeconomic status (SES) is associated with stroke incidence and mortality. Distribution of stroke risk factors is changing worldwide; evidence on these…”
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How and why weight stigma drives the obesity 'epidemic' and harms health by Tomiyama, A Janet, Carr, Deborah, Granberg, Ellen M, Major, Brenda, Robinson, Eric, Sutin, Angelina R, Brewis, Alexandra

“…In an era when obesity prevalence is high throughout much of the world, there is a correspondingly pervasive and strong culture of weight stigma. For example,…”
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Effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern: a systematic review and meta-analysis by Zeng, Baoqi, Gao, Le, Zhou, Qingxin, Yu, Kai, Sun, Feng

“…It was urgent and necessary to synthesize the evidence for vaccine effectiveness (VE) against SARS-CoV-2 variants of concern (VOC). We conducted a systematic…”
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