Search Results - "BLONDIN, Denis P"

Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation by Blondin, Denis P., Nielsen, Soren, Kuipers, Eline N., Severinsen, Mai C., Jensen, Verena H., Miard, Stéphanie, Jespersen, Naja Z., Kooijman, Sander, Boon, Mariëtte R., Fortin, Mélanie, Phoenix, Serge, Frisch, Frédérique, Guérin, Brigitte, Turcotte, Éric E., Haman, François, Richard, Denis, Picard, Frédéric, Rensen, Patrick C.N., Scheele, Camilla, Carpentier, André C.

“…Stimulation of brown adipose tissue (BAT) thermogenesis in humans has emerged as an attractive target to improve metabolic health. Pharmacological stimulations…”
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Inhibition of Intracellular Triglyceride Lipolysis Suppresses Cold-Induced Brown Adipose Tissue Metabolism and Increases Shivering in Humans by Blondin, Denis P., Frisch, Frédérique, Phoenix, Serge, Guérin, Brigitte, Turcotte, Éric E., Haman, François, Richard, Denis, Carpentier, André C.

“…Indirect evidence from human studies suggests that brown adipose tissue (BAT) thermogenesis is fueled predominantly by fatty acids hydrolyzed from…”
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Brown Adipose Tissue Energy Metabolism in Humans by Carpentier, André C, Blondin, Denis P, Virtanen, Kirsi A, Richard, Denis, Haman, François, Turcotte, Éric E

“…The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily using positron emission tomography coupled to computed tomography…”
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Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans by Ouellet, Véronique, Labbé, Sébastien M, Blondin, Denis P, Phoenix, Serge, Guérin, Brigitte, Haman, François, Turcotte, Eric E, Richard, Denis, Carpentier, André C

“…Brown adipose tissue (BAT) is vital for proper thermogenesis during cold exposure in rodents, but until recently its presence in adult humans and its…”
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Contributions of white and brown adipose tissues and skeletal muscles to acute cold‐induced metabolic responses in healthy men by Blondin, Denis P., Labbé, Sébastien M., Phoenix, Serge, Guérin, Brigitte, Turcotte, Éric E., Richard, Denis, Carpentier, André C., Haman, François

“…Key points Both brown adipose tissue (BAT) and skeletal muscle activation contribute to the metabolic response of acute cold exposure in healthy men even under…”
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Dietary fatty acid metabolism of brown adipose tissue in cold-acclimated men by Blondin, Denis P., Tingelstad, Hans C., Noll, Christophe, Frisch, Frédérique, Phoenix, Serge, Guérin, Brigitte, Turcotte, Éric E, Richard, Denis, Haman, François, Carpentier, André C.

“…In rodents, brown adipose tissue (BAT) plays an important role in producing heat to defend against the cold and can metabolize large amounts of dietary fatty…”
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Increased Brown Adipose Tissue Oxidative Capacity in Cold-Acclimated Humans by Blondin, Denis P, Labbé, Sébastien M, Tingelstad, Hans C, Noll, Christophe, Kunach, Margaret, Phoenix, Serge, Guérin, Brigitte, Turcotte, Éric E, Carpentier, André C, Richard, Denis, Haman, François

“…Context: Recent studies examining brown adipose tissue (BAT) metabolism in adult humans have provided convincing evidence of its thermogenic potential and role…”
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Recent advances in the detection of brown adipose tissue in adult humans: a review by Ong, Frank J, Ahmed, Basma A, Oreskovich, Stephan M, Blondin, Denis P, Haq, Tahniyah, Konyer, Norman B, Noseworthy, Michael D, Haman, Francois, Carpentier, Andre C, Morrison, Katherine M, Steinberg, Gregory R

“…The activation of brown adipose tissue (BAT) is associated with reductions in circulating lipids and glucose in rodents and contributes to energy expenditure…”
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Four‐week cold acclimation in adult humans shifts uncoupling thermogenesis from skeletal muscles to brown adipose tissue by Blondin, Denis P., Daoud, Amani, Taylor, Taryn, Tingelstad, Hans C., Bézaire, Véronic, Richard, Denis, Carpentier, André C., Taylor, Albert W., Harper, Mary‐Ellen, Aguer, Céline, Haman, François

“…Key points Muscle‐derived thermogenesis during acute cold exposure in humans consists of a combination of cold‐induced increases in skeletal muscle proton leak…”
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Challenges in tackling energy expenditure as obesity therapy: From preclinical models to clinical application by Löffler, Mona C., Betz, Matthias J., Blondin, Denis P., Augustin, Robert, Sharma, Anand K., Tseng, Yu-Hua, Scheele, Camilla, Zimdahl, Heike, Mark, Michael, Hennige, Anita M., Wolfrum, Christian, Langhans, Wolfgang, Hamilton, Bradford S., Neubauer, Heike

“…A chronic imbalance of energy intake and energy expenditure results in excess fat storage. The obesity often caused by this overweight is detrimental to the…”
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The role of BAT in cardiometabolic disorders and aging by Blondin, Denis P, Carpentier, André C., Dr

“…Abstract The demonstration of the presence of metabolically active brown adipose tissue (BAT) in adult humans using positron emission tomography (PET) over the…”
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Elite Male Volleyball Players Are at Risk of Insufficient Energy and Carbohydrate Intake by Sesbreno, Erik, Dziedzic, Christine E, Sygo, Jennifer, Blondin, Denis P, Haman, François, Leclerc, Suzanne, Brazeau, Anne-Sophie, Mountjoy, Margo

“…Elite volleyball athletes experience significant physical and psychological demands during the competitive season. The aim was to compare the dietary intake of…”
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Human thermogenic adipose tissue by Blondin, Denis P

“…Human thermogenic adipose tissue has long been touted as a promising therapeutic target for obesity and its associated metabolic diseases. Here, we provide a…”
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Relationship between the Daily Rhythm of Distal Skin Temperature and Brown Adipose Tissue 18F-FDG Uptake in Young Sedentary Adults by Acosta, Francisco M., Martinez-Tellez, Borja, Blondin, Denis P., Haman, François, Rensen, Patrick C. N., Llamas-Elvira, Jose M., Martinez-Nicolas, Antonio, Ruiz, Jonatan R.

“…The present study examines whether the daily rhythm of distal skin temperature (DST) is associated with brown adipose tissue (BAT) metabolism as determined by…”
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Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota by Ahmed, Basma A., Ong, Frank J., Barra, Nicole G., Blondin, Denis P., Gunn, Elizabeth, Oreskovich, Stephan M., Szamosi, Jake C., Syed, Saad A., Hutchings, Emily K., Konyer, Norman B., Singh, Nina P., Yabut, Julian M., Desjardins, Eric M., Anhê, Fernando F., Foley, Kevin P., Holloway, Alison C., Noseworthy, Michael D., Haman, Francois, Carpentier, Andre C., Surette, Michael G., Schertzer, Jonathan D., Punthakee, Zubin, Steinberg, Gregory R., Morrison, Katherine M.

“…In rodents, lower brown adipose tissue (BAT) activity is associated with greater liver steatosis and changes in the gut microbiome. However, little is known…”
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Determination of a pharmacokinetic model for [11C]-acetate in brown adipose tissue by Richard, Marie Anne, Blondin, Denis P., Noll, Christophe, Lebel, Réjean, Lepage, Martin, Carpentier, André C.

“…Background [ 11 C]-acetate positron emission tomography is used to assess oxidative metabolism in various tissues including the heart, tumor, and brown adipose…”
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A double-edged sword: risks and benefits of heat for human health by Pallubinsky, Hannah, Blondin, Denis P., Jay, Ollie

“…Extreme heat events will become more frequent and intense across the globe. In this Science & Society article we summarize how heat affects our body and…”
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Brown Adipose Tissue—A Translational Perspective by Carpentier, André C, Blondin, Denis P, Haman, François, Richard, Denis

“…Abstract Brown adipose tissue (BAT) displays the unique capacity to generate heat through uncoupled oxidative phosphorylation that makes it a very attractive…”
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Shivering and nonshivering thermogenesis in skeletal muscles by Blondin, Denis P, Haman, François

“…Humans have inherited complex neural circuits which drive behavioral, somatic, and autonomic thermoregulatory responses to defend their body temperature. While…”
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Examining the benefits of cold exposure as a therapeutic strategy for obesity and type 2 diabetes by Ivanova, Yoanna M, Blondin, Denis P

“…The pathogenesis of metabolic diseases such as obesity and type 2 diabetes are characterized by a progressive dysregulation in energy partitioning, often…”
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