Search Results - "BLOMEKE, B"

No major role for glutathione S-transferase gene polymorphisms in sensitization to para-phenylenediamine and other xenobiotics: a study of association and a meta-analysis by Pot, L.M., Alizadeh, B.Z., Ahrenberg, D., Coenraads, P.-J., Snieder, H., Blömeke, B.

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p53 and K-ras mutations in lung cancers from former and never-smoking women by VÄHÄKANGAS, Kirsi H, BENNETT, William P, CASTREN, Katariina, WELSH, Judith A, KHAN, Mohammed A, BLÖMEKE, Brunhilde, ALAVANJA, Michael C. R, HARRIS, Curtis C

“…Somatic p53 mutations are common in lung cancer. Active cigarette smoking is positively correlated with the total frequency of p53 mutations and G:C to T:A…”
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Environmental tobacco smoke, genetic susceptibility, and risk of lung cancer in never-smoking women by BENNETT, W. P, ALAVANJA, M. C. R, BLOMEKE, B, VÄHÄKANGAS, K. H, CASTREN, K, WELSH, J. A, BOWMAN, E. D, KHAN, M. A, FLIEDER, D. B, HARRIS, C. C

“…Exposure to environmental tobacco smoke (ETS) is considered to be a major lung cancer risk factor for never smokers. We investigated the hypothesis that…”
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Functional expression of N‐acetyltransferase 1 in differentiated human skin keratinocytes by Lichter, J., Bock, U., Lotz, C., Groeber, F., Blömeke, B.

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Human lung carcinogen-DNA adduct levels mediated by genetic polymorphisms in vivo by Kato, S, Bowman, E D, Harrington, A M, Blomeke, B, Shields, P G

“…Cancer risk from exposure to tobacco smoke varies widely from person to person, depending in part on the status of particular genes and acquired…”
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Skin sensitization to fragrance hydroperoxides: interplay between dendritic cells, keratinocytes and free radicals by Lichter, J., Silva e Sousa, M., Peter, N., Sahli, F., Vileno, B., Kuresepi, S., Gourlaouen, C., Giménez‐Arnau, E., Blömeke, B.

“…Summary Background Skin sensitization to hydroperoxides (R‐OOHs) of the commonly used fragrance terpenes limonene, linalool and citronellol is frequently…”
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Continuous usage of a hair dye product containing 2-methoxymethyl-para-phenylenediamine by hair-dye-allergic individuals by Kock, M., Coenraads, P.-J., Blömeke, B., Goebel, C.

“…Summary Background Despite a positive patch test reaction to para‐phenylenediamine (PPD) and/or toluene‐2,5‐diamine (PTD), many people attempt to continue…”
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Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine under hair dye use conditions in p-phenylenediamine-allergic individuals by Blömeke, B., Pot, L.M., Coenraads, P.-J., Hennen, J., Kock, M., Goebel, C.

“…Summary Background The factors influencing elicitation responses in individuals allergic to p‐phenylenediamine (PPD) in hair dyes are not well understood…”
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Assessment of the elicitation response in subjects weakly sensitized to p-phenylenediamine by Pot, L.M., Coenraads, P.J., Goebel, C., Blömeke, B.

“…Summary Background A 30‐min application of a hair dye product containing 2% p‐phenylenediamine (PPD) to subjects diagnostically graded +, showed that 12 of 18…”
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Common fragrance chemicals activate dendritic cells in coculture with keratinocytes by Peter, Niklas, Lichter, Jutta, Hagvall, Lina, Bock, Udo, Blömeke, Brunhilde

“…Background Fragrances are important contact allergens; however, investigation of their skin sensitization potency has been challenging in new approach methods…”
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Association between TNFA-308 G/A polymorphism and sensitization to para-phenylenediamine: a case-control study by Blömeke, B, Brans, R, Dickel, H, Bruckner, T, Erdmann, S, Heesen, M, Merk, H.F, Coenraads, P.-J

“…Para-phenylenediamine (PPD) and related chemicals are common contact sensitizers, frequently causing allergic contact dermatitis (ACD). The cytokine tumor…”
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Elicitation of the immune response to p-phenylenediamine in allergic patients: the role of dose and exposure time by Goebel, C., Coenraads, P.-J., Rothe, H., Kunze, G., Kock, M., Schlatter, H., Gerberick, G.F., Blömeke, B.

“…Summary Background  Usage of hair dye products containing p‐phenylenediamine (PPD) is a concern for PPD‐allergic individuals. Objectives  The present study…”
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Para-phenylenediamine and allergic sensitization: risk modification by N-acetyltransferase 1 and 2 genotypes by Blömeke, B., Brans, R., Coenraads, P.-J., Dickel, H., Bruckner, T., Hein, D.W., Heesen, M., Merk, H.-F., Kawakubo, Y.

“…Summary Background  Para‐phenylenediamine (PPD) is a common contact sensitizer causing allergic contact dermatitis, a major skin problem. As PPD may need…”
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Distribution of 7-alkyl-2'-deoxyguanosine adduct levels in human lung by Blömeke, Brunhilde, Greenblatt, Michael J., Van Doan, D., Bowman, Elise D., Murphy, Sharon E., Chen, Clara C., Kato, Shunji, Shields, Peter G.

“…Human lung tissue is frequently studied as a target organ for DNA damage from carcinogen-DNA adducts. In order to assess the distribution of carcinogen-DNA…”
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N-Acetylation of paraphenylenediamine in human skin and keratinocytes by Kawakubo, Y, Merk, H F, Masaoudi, T A, Sieben, S, Blömeke, B

“…Skin is the major target of allergic reactions to paraphenylenediamine (PPD). Such small molecules require activation to become immunogenic. The balance…”
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Lack of association between the -260 C→T promoter polymorphism of the endotoxin receptor CD14 gene and the CD14 density of unstimulated human monocytes and soluble CD14 plasma levels by HEESEN, Michael, BLÖMEKE, Brunhilde, SCHLÜTER, Bernhard, HEUSSEN, Nicole, ROSSAINT, Rolf, KUNZ, Dagmar

“…CD14 is a receptor for endotoxin and binds components of Gram-positive and Gram-negative bacteria. CD14-bearing monocytes respond to stimulation with the…”
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Evaluation of DNA-binding activity of hydroxyanthraquinones occurring in Rubia tinctorum L by Poginsky, B, Westendorf, J, Blömeke, B, Marquardt, H, Hewer, A, Grover, P L, Phillips, D H

“…The naturally-occurring anthraquinones (AQs), alizarin (1,2-dihydroxyanthraquinone) and lucidin (1,3-dihydroxy-2-hydroxymethylanthraquinone), were incubated…”
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Impact of para -phenylenediamine on cyclooxygenases expression and prostaglandin formation in human immortalized keratinocytes (HaCaT) by Moeller, Ruth, Lichter, Jutta, Blömeke, Brunhilde

“…Abstract para -Phenylenediamine, a monocyclic arylamine, is a frequently used chemical and ingredient of oxidative hair coloring products. Thus exposure occurs…”
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THP-1 in Coculture with HaCaT Keratinocytes (COCAT) for an advanced in vitro prediction of sensitization potential and potency of chemicals by Hennen, J., Blömeke, B.

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Characterization of T Cell Responses to Fragrances by Sieben, Sonja, Hertl, Michael, Al Masaoudi, Tames, Merk, Hans F., Blömeke, Brunhilde

“…Fragrances are worldwide a major cause of allergic contact dermatitis (ACD), a delayed-type hypersensitivity reaction mediated by T lymphocytes. We…”
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