Search Results - "BLOKSMA, Nanne"

Indoleamine 2,3-dioxygenase–dependent tryptophan metabolites contribute to tolerance induction during allergen immunotherapy in a mouse model by Taher, Yousef A., MSc, Piavaux, Benoit J.A., MSc, Gras, Reneé, BSc, van Esch, Betty C.A.M., BSc, Hofman, Gerard A., BSc, Bloksma, Nanne, PhD, Henricks, Paul A.J., PhD, van Oosterhout, Antoon J.M., PhD

“…Background The tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO) has been implicated in immune suppression and tolerance induction. Objective We…”
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Induction of HSP70 is dispensable for anti-inflammatory action of heat shock or NSAIDs in mast cells by Mortaz, Esmaeil, Redegeld, Frank A., Bloksma, Nanne, Dunsmore, Kathy, Denenberg, Alvin, Wong, Hector R., Nijkamp, Frans P., Engels, Ferdi

“…It is well known that nonsteroidal anti-inflammatory drugs (NSAIDs), such as acetylsalicylic acid, ibuprofen, and indomethacin, induce anti-inflammatory…”
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Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro by Valstar, Dingena L, Schijf, Marcel A, Stelekati, Erietta, Nijkamp, Frans P, Bloksma, Nanne, Henricks, Paul A J

“…Occupational exposure to airborne low molecular weight chemicals, like trimellitic anhydride (TMA), can result in occupational asthma. Alveolar macrophages…”
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Predictive testing for pathogenic autoimmunity: the morphological approach by Kuper, C.Frieke, Schuurman, Henk-Jan, Bos-Kuijpers, Marga, Bloksma, Nanne

“…The term autoimmunity refers to physiologically normal immune processes against self-antigens. In rare cases, the regulatory mechanisms become deflective and…”
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Effects of the T cell inhibitor, cyclosporin A (CsA), on hexachlorobenzene (HCB)-induced immunopathology in the Brown Norway (BN) rat by Bloksma, Nanne

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RESPIRATORY IRRITATION BY TRIMELLITIC ANHYDRIDE IN BROWN NORWAY AND WISTAR RATS by Arts, J H, de Koning, M W, Bloksma, N, Kuper, C F

“…Several acid anhydrides are known for their sensitizing and irritative properties. Since both irritation and respiratory allergy can cause changes of lung…”
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Humic acid enhances cigarette smoke-induced lung emphysema in mice and IL-8 release of human monocytes by van Eijl, Sven, Mortaz, Esmaeil, Ferreira, Ana F, Kuper, Frieke, Nijkamp, Frans. P, Folkerts, Gert, Bloksma, Nanne

“…Abstract Tobacco smoke is the main factor in the etiology of lung emphysema. Generally prolonged, substantial exposure is required to develop the disease…”
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The contact allergen dinitrochlorobenzene (DNCB) and respiratory allergy in the Th2-prone Brown Norway rat by Kuper, C. Frieke, Stierum, Rob H, Boorsma, Andre, Schijf, Marcel A, Prinsen, Menk, Bruijntjes, Joost P, Bloksma, Nanne, Arts, Josje H.E

“…Abstract All LMW respiratory allergens known to date can also induce skin allergy in test animals. The question here was if in turn skin allergens can induce…”
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Respiratory allergy and pulmonary irritation to trimellitic anhydride in Brown Norway rats by Arts, Josje H.E, Bloksma, Nanne, Leusink-Muis, Thea, Kuper, C.Frieke

“…Occupational exposure to low-molecular-weight (LMW) allergens such as acid anhydrides can result in occupational asthma, an allergic disease characterized by…”
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Influence of the macrophage bacterial resistance gene Nramp1 (Slc11a1) on the induction of allergic asthma in the mouse by Smit, Joost J., Van Loveren, Henk, Hoekstra, Maarten O., Nijkamp, Frans P., Bloksma, Nanne

“…ABSTRACT Based on the hygiene hypothesis that lack of early childhood bacterial infections would favor development of allergic disease, we hypothesize that…”
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Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin by VALSTAR, Dingena L, SCHIJF, Marcel A, ARTS, Josje H. E, FRIEKE KUPER, C, NIJKAMP, Frans P, STORM, Gert, BLOKSMA, Nanne, HENRICKS, Paul A. J

“…Occupational exposure to low molecular weight chemicals, like trimellitic anhydride (TMA), can result in occupational asthma. Alveolar macrophages (AMs) are…”
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Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma by Valstar, Dingena L., Schijf, Marcel A., Nijkamp, Frans P., Storm, Gert, Arts, Josje H.E., Kuper, C. Frieke, Bloksma, Nanne, Henricks, Paul A.J.

“…Occupational exposure to low molecular weight chemicals, like trimellitic anhydride (TMA), can result in occupational asthma. Alveolar macrophages (AMs) are…”
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Airway Morphology and Function of Rats Following Dermal Sensitization and Respiratory Challenge with Low Molecular Weight Chemicals by Arts, Josje H.E., Kuper, C.Frieke, Spoor, Stan M., Bloksma, Nanne

“…Local lymph node activation and increased total serum IgE levels are suggested to be predictive parameters of airway hypersensitivity caused by low molecular…”
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Respiratory Allergy to Trimellitic Anhydride in Rats: Concentration-Response Relationships During Elicitation by Arts, Josje H. E., de Koning, Martijn W., Bloksma, Nanne, Kuper, C. Frieke

“…The present study investigated whether airway responses of sensitized rats to trimellitic anhydride (TMA) were concentration dependent and whether these were…”
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Glutathione and other low-molecular-weight thiols relax guinea pig trachea ex vivo: interactions with nitric oxide? by Kloek, Joris, van Ark, Ingrid, Bloksma, Nanne, De Clerck, Fred, Nijkamp, Frans P, Folkerts, Gert

“…The aim of this study was to determine the effects of glutathione (GSH) on trachea smooth muscle tension in view of previously reported interactions between…”
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Effects of lactobacilli on parameters of non-specific resistance of mice by Bloksma, N, Ettekoven, H, Hofhuis, F M, van Noorle-Jansen, L, De Reuver, M J, Kreeftenberg, J G, Willers, J M

“…The viability of Lactobacillus plantarum in vivo and the effects of viable and heat-killed lactobacilli on parameters of non-specific resistance were studied…”
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Effect of adrenoceptor blockade on hemorrhagic necrosis of meth A sarcomata induced by endotoxin or tumor necrosis serum by Bloksma, N, Hofhuis, F M, Willers, J M

“…An intravenous injection of endotoxin into BALB/c mice bearing subcutaneous Meth A sarcomata caused hemorrhagic necrosis and reduced growth of the tumors. In a…”
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RESPIRATORY IRRITATION BY TRIMELLITIC ANHYDRIDE IN BROWN NORWAY AND WISTAR RATS by Arts, Josje H. E., de Koning, Martijn W., Bloksma, Nanne, Kuper, C. Frieke

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Predictive immunotoxicological test systems: suitability of the popliteal lymph node assay in mice and rats by Bloksma, N, Kubicka-Muranyi, M, Schuppe, H C, Gleichmann, E, Gleichmann, H

“…This article reviews results obtained with popliteal lymph node assays (PLNAs) in rodents and discusses their ability to detect and analyze immunotoxic effects…”
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Hexachlorobenzene-Induced Eosinophilic and Granulomatous Lung Inflammation Is Associated with in Vivo Airways Hyperresponsiveness in the Brown Norway Rat by Michielsen, Carola P.P.C., Leusink-Muis, Ateunette, Vos, Joseph G., Bloksma, Nanne

“…We investigated whether the eosinophilic and granulomatous lung pathology that develops in Brown Norway (BN/SsNOlaHsd) rats upon feeding hexachlorobenzene…”
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