Search Results - "BLOCK, Alan J"

Update on Fibrocartilaginous Disease Clinical Examination by Butterworth, Michelle L., Block, Alan J.

“…This article provides an update on fibrocartilaginous disease clinical examination. Lesser metatarsophalangeal joint instability is a challenging entity for…”
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Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial by Ruperto, Nicolino, MD, Lovell, Daniel J, Prof, Quartier, Pierre, MD, Paz, Eliana, MD, Rubio-Pérez, Nadina, MD, Silva, Clovis A, MD, Abud-Mendoza, Carlos, MD, Burgos-Vargas, Ruben, Prof, Gerloni, Valeria, MD, Melo-Gomes, Jose A, MD, Saad-Magalhães, Claudia, MD, Sztajnbok, Flavio, MD, Goldenstein-Schainberg, Claudia, MD, Scheinberg, Morton, MD, Penades, Immaculada Calvo, MD, Fischbach, Michael, MD, Orozco, Javier, MD, Hashkes, Philip J, MD, Hom, Christine, MD, Jung, Lawrence, MD, Lepore, Loredana, MD, Oliveira, Sheila, MD, Wallace, Carol A, Prof, Sigal, Leonard H, Prof, Block, Alan J, PhD, Covucci, Allison, MS, Martini, Alberto, Prof, Giannini, Edward H, Prof

“…Summary Background Some children with juvenile idiopathic arthritis either do not respond, or are intolerant to, treatment with disease-modifying antirheumatic…”
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Long‐Term Safety, Efficacy, and Quality of Life in Patients With Juvenile Idiopathic Arthritis Treated With Intravenous Abatacept for Up to Seven Years by Lovell, Daniel J., Ruperto, Nicolino, Mouy, Richard, Paz, Eliana, Rubio‐Pérez, Nadina, Silva, Clovis A., Abud‐Mendoza, Carlos, Burgos‐Vargas, Ruben, Gerloni, Valeria, Melo‐Gomes, Jose A., Saad‐Magalhaes, Claudia, Chavez‐Corrales, J., Huemer, Christian, Kivitz, Alan, Blanco, Francisco J., Foeldvari, Ivan, Hofer, Michael, Huppertz, Hans‐Iko, Job Deslandre, Chantal, Minden, Kirsten, Punaro, Marilynn, Block, Alan J., Giannini, Edward H., Martini, Alberto

“…Objective The efficacy and safety of abatacept in patients with juvenile idiopathic arthritis (JIA) who experienced an inadequate response to disease‐modifying…”
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Determinants of elevated pulse pressure in middle-aged and older subjects with uncomplicated systolic hypertension: The role of proximal aortic diameter and the aortic pressure-flow relationship by MITCHELL, Gary F, LACOURCIERE, Yves, OUELLET, Jean-Pascal, IZZO, Joseph L, NEUTEL, Joel, KERWIN, Linda J, BLOCK, Alan J, PFEFFER, Marc A

“…Elevated pulse pressure (PP) is associated with increased cardiovascular risk and is thought to be secondary to elastin fragmentation with secondary collagen…”
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Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial by Rouleau, Jean L, Pfeffer, Marc A, Stewart, Duncan J, Isaac, Debra, Sestier, Francois, Kerut, Edmund K, Porter, Charles B, Proulx, Guy, Qian, Chunlin, Block, Alan J

“…We aimed to assess in patients with congestive heart failure whether dual inhibition of neutral endopeptidase and angiotensin-converting enzyme (ACE) with the…”
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Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: Results of the conduit hemodynamics of omapatrilat international research study by MITCHELL, Gary F, IZZO, Joseph L, LACOURCIERE, Yves, OUELLET, Jean-Pascal, NEUTEL, Joel, CHUNLIN QIAN, KERWIN, Linda J, BLOCK, Alan J, PFEFFER, Marc A

“…Increased pulse pressure, an indicator of conduit vessel stiffness, is a strong independent predictor of cardiovascular events in hypertensive cohorts, which…”
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Treatment of Recalcitrant Intermetatarsal Neuroma With 4% Sclerosing Alcohol Injection: A Pilot Study by Hyer, Christopher F., Mehl, Lynette R., Block, Alan J., Vancourt, Robert B.

“…The purpose of this investigation was to conduct a prospective trial to assess the effectiveness of a 4% sclerosing alcohol injection in a small group of…”
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Evaluation of the anterior and middle talocalcaneal articular facets and the evans osteotomy by Hyer, Christopher F., Lee, Thomas, Block, Alan J., VanCourt, Robert

“…The purpose of this study was to determine the occurrence of discrete anterior and middle talocalcaneal facets and the distance of these facets from the…”
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Long‐term safety and efficacy of abatacept in children with juvenile idiopathic arthritis by Ruperto, Nicolino, Lovell, Daniel J., Quartier, Pierre, Paz, Eliana, Rubio‐Pérez, Nadina, Silva, Clovis A., Abud‐Mendoza, Carlos, Burgos‐Vargas, Ruben, Gerloni, Valeria, Melo‐Gomes, Jose A., Saad‐Magalhães, Claudia, Chavez‐Corrales, J., Huemer, Christian, Kivitz, Alan, Blanco, Francisco J., Foeldvari, Ivan, Hofer, Michael, Horneff, Gerd, Huppertz, Hans‐Iko, Job‐Deslandre, Chantal, Loy, Anna, Minden, Kirsten, Punaro, Marilynn, Nunez, Alejandro Flores, Sigal, Leonard H., Block, Alan J., Nys, Marleen, Martini, Alberto, Giannini, Edward H.

“…Objective We previously documented that abatacept was effective and safe in patients with juvenile idiopathic arthritis (JIA) who had not previously achieved a…”
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OR-37: Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension. Results of the conduit hemodynamics of omapatrilat international research (CHOIR) study by Mitchell, Gary F., Lacourcière, Yves, Ouellet, Jean-Pascal, Izzo, Joseph, Neutel, Joel, Qian, Chunlin, Kerwin, Linda J., Block, Alan J., Pfeffer, Marc A.

“…Pulse pressure has recently emerged as a strong independent predictor of cardiovascular events in the general population and in essential hypertension (EH)…”
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Conduit vessel stiffness is increased in central but not peripheral conduit arteries in adults with essential hypertension by Mitchell, Gary F., Lacourcière, Yves, Ouellet, Jean-Pascal, Izzo, Joseph L., Neutel, Joel M., Smith, Kent, Qian, Chunlin, Kerwin, Linda J., Block, Alan J., Pfeffer, Marc A.

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Reducing the risk of wound infections. Examining the role of antimicrobial resistance in the management of lower extremity infections by Block, Alan J

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A169: Cumulative Long‐Term Safety, Efficacy and Patient‐Reported Outcomes in Children With Juvenile Idiopathic Arthritis Treated With Intravenous Abatacept: Up to 7 Years of Treatment by Lovell, Daniel J., Ruperto, Nicolino, Mouy, Richard, Paz, Eliana, Rubio‐Perez, Nadina, Silva, Clovis A., Abud‐Mendoza, Carlos, Burgos‐Vargas, Ruben, Gerloni, Valeria, Melo‐Gomes, Jose A., Magalhaes, Claudia Saad, Chavez‐Corrales, Jose, Huemer, Christian, Kivitz, Alan J., Blanco, Francisco J., Foeldvari, Ivan, Hofer, Michael, Huppertz, Hans‐Iko, Deslandre, Chantal, Minden, Kirsten, Block, Alan J., Giannini, Edward H., Martini, Alberto

“…Background/Purpose: The long‐term efficacy and safety of intravenous abatacept in patients (pts) with juvenile idiopathic arthritis (JIA) have been reported…”
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Stereoselectivity of tocainide pharmacodynamics in vivo and in vitro by Block, A J, Merrill, D, Smith, E R

“…Racemic tocainide [R,S-T], which is used in the treatment of ventricular arrhythmias, consists of an R(-)-enantiomer [R-T] and an S(+)-enantiomer [S-T]. The…”
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On the kinetics and dynamics of tocainide and its metabolites by Ronfeld, R A, Wolshin, E M, Block, A J

“…The kinetics of tocainide, a new antiarrhythmic, and two of its metabolites, lactoxylidide (LX) and tocainide carbamoyl glucuronide (TG), were examined in…”
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Modification of basal release of prostaglandins from rabbit isolated hearts by Block, A J, Poole, S, Vane, J R

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Abatacept in children with juvenile idiopathic arthritis : a randomised, double-blind, placebo-controlled withdrawal trial. Commentary by LEHMAN, Thomas J. A, RUPERTO, Nicolino, MELO-GOMES, Jose A, SAAD-MAGALHAES, Claudia, SZTAJNBOK, Flavio, GOLDENSTEIN-SCHAINBERG, Claudia, SCHEINBERG, Morton, CALVO PENADES, Immaculada, FISCHBACH, Michael, OROZCO, Javier, HASHKES, Philip J, HOM, Christine, LOVELL, Daniel J, JUNG, Lawrence, LEPORE, Loredana, OLIVEIRA, Sheila, WALLACE, Carol A, SIGAL, Leonard H, BLOCK, Alan J, COVUCCI, Allison, MARTINI, Alberto, GIANNINI, Edward H, QUARTIER, Pierre, PAZ, Eliana, RUBIO-PEREZ, Nadina, SILVA, Clovis A, ABUD-MENDOZA, Carlos, BURGOS-VARGAS, Ruben, GERLONI, Valeria

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New antiarrhythmic agents. 6. Quantitative structure-activity relationships of aminoxylidides by Tenthorey, Paul A, Block, Alan J, Ronfeld, Robert A, McMaster, Paul D, Byrnes, Eugene W

“…The synthesis and pharmacological evaluation of primary and tertiary aminoxylidides with the amino group in the 2-7 position of the acyl chain are described…”
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New antiarrhythmic agents. 5. .alpha.-Aminoaceto-2,6-xylidides with functionalized amide alkyl substituents by McMaster, Paul D, Byrnes, Eugene W, Block, Alan J, Tenthorey, Paul A

“…The synthesis of aminoaceto-2',6'-xylidides substituted on the amide nitrogen with 2-(diethylamino)ethyl, 2-aminoethyl, 2-hydroxyethyl, and 2-ethoxyethyl…”
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A health perception score predicts cardiac events in patients with heart failure: Results from the IMPRESS trial by Havranek, Edward P., Lapuerta, Pablo, Simon, Teresa A., L'Italien, Gilbert, Block, Alan J., Rouleau, Jean L.

“…Background: New York Heart Association (NYHA) class and treadmill exercise test variables are widely used for estimating prognosis and measuring the outcomes…”
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