Search Results - "BLESSING, Robert"

The IMAGINE instrument: first neutron protein structure and new capabilities for neutron macromolecular crystallography by Meilleur, Flora, Munshi, Parthapratim, Robertson, Lee, Stoica, Alexandru D., Crow, Lowell, Kovalevsky, Andrey, Koritsanszky, Tibor, Chakoumakos, Bryan C., Blessing, Robert, Myles, Dean A. A.

“…The first high‐resolution neutron protein structure of perdeuterated rubredoxin from Pyrococcus furiosus (PfRd) determined using the new IMAGINE macromolecular…”
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Novel diagnostic test for acute stroke by LYNCH, John R, BLESSING, Robert, WHITE, William D, GROCOTT, Hilary P, NEWMAN, Mark F, LASKOWITZ, Daniel T

“…The absence of a widely available and sensitive diagnostic test for acute cerebral ischemia remains a significant limitation in the diagnosis and management of…”
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Routine 24-Hour Computed Tomography Brain Scan is not useful in stable patients Post Intravenous Tissue Plasminogen Activator by Guhwe, Mary, DNP, Utley-Smith, Queen, EdD, Blessing, Robert, DNP, Goldstein, Larry B., MD

“…Background Obtaining a routine computed tomography (CT) brain scan 24 hours after treatment with intravenous tissue plasminogen activator (IV-tPA) is included…”
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Risk of cerebral vasopasm after subarachnoid hemorrhage reduced by statin therapy : a multivariate analysis of an institutional experience by MCGIRT, Matthew J, BLESSING, Robert, ALEXANDER, Michael J, NIMJEE, Shahid M, WOODWORTH, Graeme F, FRIEDMAN, Allan H, GRAFFAGNINO, Carmelo, LASKOWITZ, Daniel T, LYNCH, John R

“…Impairment of endothelial nitric oxide synthase (eNOS), endothelium-dependent relaxation, and cerebrovascular autoregulation all occur in vasospastic cerebral…”
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SUSPECTED DAPTOMYCIN-INDUCED EOSINOPHILLIC PNEUMONIA by FYFFE, ZACHARY, BLESSING, ROBERT

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Serum von Willebrand factor, matrix metalloproteinase-9, and vascular endothelial growth factor levels predict the onset of cerebral vasospasm after aneurysmal subarachnoid hemorrhage by MCGIRT, Matthew J, LYNCH, John R, BLESSING, Robert, WARNER, David S, FRIEDMAN, Allan H, LASKOWITZ, Daniel T, AWAD, Issam A, FINDLAY, J. Max, LAWTON, Michael T, FRIEDLANDER, Robert M

“…Endothelial damage and intimal proliferation occur in vasospastic cerebral arteries after subarachnoid hemorrhage (SAH). In the peripheral vasculature,…”
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Apolipoprotein E Modifies Neurological Outcome by Affecting Cerebral Edema but not Hematoma Size after Intracerebral Hemorrhage in Humans by James, Michael L., MD, Blessing, Robert, RN, ACNP, Bennett, Ellen, PhD, Laskowitz, Daniel T., MD

“…Introduction To address the mechanisms by which apoE polymorphism affects functional outcome after intracerebral hemorrhage in humans, we tested the hypothesis…”
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Topological analysis of experimental electron densities by Souhassou, Mohamed, Blessing, Robert H.

“…Practical computing algorithms are described for analysing the topology of experimental electron density distributions represented as either three‐dimensional…”
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The structure of T6 human insulin at 1.0 Å resolution by Smith, G. David, Pangborn, Walter A., Blessing, Robert H.

“…The structure of T6 human insulin has been determined at 120 K at a resolution of 1.0 Å and refined to a residual of 0.183. As a result of cryofreezing, the…”
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Accurate Protein Crystallography at Ultra-High Resolution: Valence Electron Distribution in Crambin by Jelsch, Christian, Teeter, Martha M., Lamzin, Victor, Pichon-Pesme, Virginie, Blessing, Robert H., Lecomte, Claude

“…The charge density distribution of a protein has been refined experimentally. Diffraction data for a crambin crystal were measured to ultra-high resolution…”
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AN UNEXPECTED ETIOLOGY OF RESPIRATORY FAILURE DURING COVID-19 PANDEMIC by BUNDY, ALYSON, BLESSING, ROBERT, MUNDELL, JENNIFER

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The structure of T6 bovine insulin by Smith, G. David, Pangborn, Walter A., Blessing, Robert H.

“…Porcine insulin differs in sequence from bovine insulin at residues A8 (Thr in porcine→Ala in bovine) and A10 (Ile in porcine→Val in bovine). The structure of…”
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Transcranial doppler monitoring and clinical decision-making after subarachnoid hemorrhage by McGirt, Matthew J., Blessing, Robert P., Goldstein, Larry B.

“…Our objective was to examine the impact of transcranial Doppler ultrasound (TCD) vasospasm monitoring on clinical decision-making following subarachnoid…”
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The 1.1 Å Resolution Crystal Structure of [Tyr15]EpI, a Novel α-Conotoxin from Conus episcopatus, Solved by Direct Methods by Hu, Shu-Hong, Loughnan, Marion, Miller, Russ, Weeks, Charles M, Blessing, Robert H, Alewood, Paul F, Lewis, Richard J, Martin, Jennifer L

“…Conotoxins are valuable probes of receptors and ion channels because of their small size and highly selective activity. α-Conotoxin EpI, a 16-residue peptide…”
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Difference structure-factor normalization for heavy-atom or anomalous-scattering substructure determinations by Blessing, Robert H., Smith, G. David

“…Procedures are described for normalizing structure‐factor difference magnitudes, |Δ|F||SIR = ||FDer| − |FNat|| ≤ |FHeavy| or |Δ|F||SAS = ||F+h| − |F−h|| ≤…”
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Exploring the Relationship Between Objective Pupillometry Metrics and Midline Shift by Giamarino, Kathryn, Blessing, Robert, Boelter, Christopher, Thompson, Julie A., Reynolds, Staci S.

“…BACKGROUND: Pupillary examinations provide early subtle signs of worsening intracranial pathology. Objective pupillomtery assessment, although not yet the…”
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Exploring the Relationship Between Objective Pupillometry Metrics and Midline Shift by Giamarino, Kathryn, Blessing, Robert, Boelter, Christopher, Thompson, Julie A., Reynolds, Staci S.

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In Situ Simulation to Improve Management of In-Hospital Strokes: Unexpected Challenges by Rollison, Sarah, Blessing, Robert, Kuszajewski, Michele L., Muckler, Virginia C.

“…In-hospital strokes are life-threatening emergencies that require prompt and skillful treatment to prevent poor patient outcomes. Currently, however, a…”
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Electron distributions in peptides and related molecules. 2. An experimental and theoretical study of (Z)-N-acetyl-.alpha.,.beta.-dehydrophenylalanine methylamide by Souhassou, Mohamed, Lecomte, Claude, Ghermani, Nour Eddine, Rohmer, Marie Madeleine, Wiest, Roland, Benard, Marc, Blessing, Robert H

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Outlier Treatment in Data Merging by Blessing, R. H.

“…Experience with a variety of diffraction data‐reduction problems has led to several strategies for dealing with mismeasured outliers in multiply measured data…”
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