Search Results - "BLANK, E. W"

Initial clinical evaluation of radiolabeled MX-DTPA humanized BrE-3 antibody in patients with advanced breast cancer by KRAMER, E. L, LIEBES, L, WASSERHEIT, C, NOZ, M. E, BLANK, E. W, ZABALEGUI, A, MELAMED, J, FURMANSKI, P, PETERSON, J. A, CERIANI, R. L

“…To evaluate radiometal-labeled humanized BrE-3 (huBrE-3) monoclonal antibody as a radioimmunolocalization and therapeutic agent in breast cancer patients,…”
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Conjugation of interferon alpha to a humanized monoclonal antibody (HuBrE-3vl) enhances the selective localization and antitumor effects of interferon in breast cancer xenografts by OZZELLO, L, BLANK, E. W, DE ROSA, C. M, CERIANI, R. L, TÖLÖ, H, KAUPPINEN, H.-L, CANTELL, K

“…Human mammary carcinoma xenografts (MCF-7) growing in nude mice were treated with natural interferon alpha (n-IFN-alpha) alone or conjugated to a humanized…”
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Effect of multiple, repeated doses of radioimmunotherapy on target antigen expression (breast MUC-1 Mucin) in breast carcinomas by PETERSON, J. A, BLANK, E. W, CERIANI, R. L

“…The effect of radioimmunotherapy (RIT) on target antigen expression was studied in breast carcinomas transplanted in immunodeficient mice. In nine separate…”
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Anti-BA46 monoclonal antibody Mc3: humanization using a novel positional consensus and in vivo and in vitro characterization by COUTO, J. R, BLANK, E. W, PETERSON, J. A, CERIANI, R. L

“…Mc3 is a murine mAb that is highly effective in treating breast tumors in experimental radioimmunotherapy. Mc3 binds to BA46, a 46-kDa glycoprotein of the…”
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Effect of dietary fat and monoclonal antibody therapy on the growth of human mammary adenocarcinoma MX-1 grafted in athymic mice by Gabor, H, Blank, E W, Ceriani, R L

“…A diet containing 11% per weight fish oils (Max-EPA) reduced the rate of growth of a transplantable human breast tumor (MX-1) grafted into immunodeficient mice…”
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Circulating Human Mammary Epithelial Antigens in Breast Cancer by Ceriani, Roberto L., Sasaki, Masao, Sussman, Howard, Wara, William M., Blank, Edward W.

“…Heterologous specific antisera against human mammary epithelial antigens (HME-Ags), which are present in the human milk fat globule membrane and breast…”
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The use of natural interferon alpha conjugated to a monoclonal antibody anti mammary epithelial mucin (Mc5) for the treatment of human breast cancer xenografts by OZZELLO, L, DE ROSA, C. M, BLANK, E. W, CANTELL, K, CERIANI, R. L, HABIF, D. V

“…An immunoconjugate composed of natural interferon alpha (nIFN alpha) bound in a noncleavable fashion to a monoclonal antibody (MoAb) recognizing a breast…”
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Evidence of extensive phospholipid fatty acid methylation during the assumed selective methylation of plasma free fatty acids by diazomethane by Lin, Chu, Blank, Edward W., Ceriani, Roberto L., Baker, Nome

“…We compared a conventional method (Method I) for measuring plasma free fatty acid (FFA) concentrations with two more rapid procedures (Method II and Method…”
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Epitope expression on the breast epithelial mucin by CERIANI, R. L, PETERSON, J. A, BLANK, E. W, LAMPORT, D. T. A

“…Multiple epitope expression on the breast epithelial mucin was explored using a panel of monoclonal antibodies (MoAbs) created against milk and breast tissue…”
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5-Iododeoxyuridine Increases the Efficacy of the Radioimmunotherapy of Human Tumors Growing in Nude Mice by Santos, Orlando, Pant, Keshab D, Blank, Edward W, Ceriani, Roberto L

“…Recently, there has been much interest in the use of radionuclide conjugated monoclonal antibodies for the treatment of human malignancies. One way to…”
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Biochemical and histological characterization of antigens preferentially expressed on the surface and cytoplasm of breast carcinoma cells identified by monoclonal antibodies against the human milk fat globule by Peterson, J A, Zava, D T, Duwe, A K, Blank, E W, Battifora, H, Ceriani, R L

“…The preparation of monoclonal antibodies (MAbs) against the human milk fat globule membrane with preferential binding to breast carcinoma cells is described…”
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Breast epithelial mucin serum clearance by Ceriani, R L, Blank, E W

“…The breast epithelial mucin is one of the currently used serum breast cancer markers. Immunoassays detect elevations of this marker in breast cancer relapse;…”
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Engineering of antibodies for breast cancer therapy: construction of chimeric and humanized versions of the murine monoclonal antibody BrE-3 by Couto, J R, Blank, E W, Peterson, J A, Kiwan, R, Padlan, E A, Ceriani, R L

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A novel serum assay for breast epithelial antigen using a fusion protein by Ceriani, R L, Larocca, D, Peterson, J A, Enloe, S, Amiya, R, Walkup, G, Blank, E W

“…Serum levels of breast epithelial antigens (BrE-Ags) are presently used in the follow-up of breast cancer patients. Available assays do not have optimal…”
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Experimental immunotherapy of breast cancer using alpha interferon conjugated to monoclonal antibody Mc5 by Ozzello, L, De Rosa, C M, Blank, E W, Cantell, K, Ceriani, R L, Habif, Sr, D V

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Comparison of rates of phenotypic variability in surface antigen expression in normal and cancerous human breast epithelial cells by PETERSON, J. A, CERIANI, R. L, BLANK, E. W, OSVALDO, L

“…A method is described for measuring the rate of phenotypic variability in normal and neoplastic breast epithelial cells. Three groups of normal human mammary…”
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Variability in surface antigen expression of human breast epithelial cells cultured from normal breast, normal tissue peripheral to breast carcinomas, and breast carcinomas by CERIANI, R. L, PETERSON, J. A, BLANK, E. W

“…Single-cell heterogeneity and variability in expression of several surface antigens on human mammary epithelial cells in short-term culture were studied with…”
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Diagnostic ability of different human milk fat globule antigens in breast cancer by CERIANI, R. L, BLANK, E. W, ROSENBAUM, E. H, BEN ZEEV, D, LOWITZ, R. S, JOHANSEN, L, TRUJILLO, T

“…Human mammary epithelial antigens (HME-Ags) are released into the circulation by breast tumors and not by normal breast tissue (Proc. Natl. Acad. Sci. USA 74:…”
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Experimental therapy of human breast tumors with 131I-labeled monoclonal antibodies prepared against the human milk fat globule by CERIANI, R. L, BLANK, E. W

“…Breast tumors are susceptible to attack by unconjugated anti-human milk fat globule monoclonal antibodies (MoAbs) and most particularly by their mixture…”
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Cloning of cDNAs encoding the variable domains of antibody BrE-3 and construction of a chimeric antibody by Couto, J R, Blank, E W, Peterson, J A, Ceriani, R L

“…BrE-3 is an IgG1,kappa murine monoclonal antibody that binds to human breast epithelial mucin and that has been shown to be promising for imaging and treatment…”
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