Search Results - "BLANCHARD, E. M"

Protection of Human Left Ventricular Myocardium From Cutting Injury With 2,3 -Butanedione Monoxime by Mulieri, Louis A, Hasenfuss, Gerd, Ittleman, Frank, Blanchard, Edward M, Alpert, Norman R

“…To prevent dissection injury when cutting strip preparations from human left ventricular papillary muscle tissue, dissections were carried out with…”
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Energetics of Isometric Force Development in Control and Volume-Overload Human Myocardium: Comparison With Animal Species by Hasenfuss, Gerd, Mulieri, Louis A, Blanchard, Edward M, Holubarsch, Christian, Leavitt, Bruce J, Ittleman, Frank, Alpert, Norman R

“…Alteration in crossbridge behavior and myocardial performance have been associated with myosin isoenzyme composition in animal models of myocardial hypertrophy…”
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Targeted Ablation of the Murine alpha-Tropomyosin Gene by Blanchard, Edward M, Iizuka, Kenji, Christe, Michael, Conner, David A, Geisterfer-Lowrance, Anja, Schoen, Frederick J, Maughan, David W, Seidman, Christine E, Seidman, J.G

“…We created a mouse that lacks a functional alpha-tropomyosin gene using gene targeting in embryonic stem cells and blastocyst-mediated transgenesis. Homozygous…”
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The effects of 2,3-butanedione monoxime on initial heat, tension, and aequorin light output of ferret papillary muscles by BLANCHARD, E. M, SMITH, G. L, ALLEN, D. G, ALPERT, N. R

“…At low concentrations (up to 5 mM) the compound 2,3-butanedione monoxime (BDM) was found to reduce twitch tension and initial heat production in isolated…”
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Inhibition of the Activation and Troponin Calcium Binding of Dog Cardiac Myofibrils by Acidic pH by Blanchard, Edward M, Solaro, R John

“…The aim of experiments described here was to test whether deactivation of cardiac myofibrils in acidic pH is associated with decreases in amounts of calcium…”
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Peripheral Blood Lymphocyte Transformation to G2s in Patients with Autoimmune Thyroid Disease with and without Ophthalmopathy by Chang, C.H., Yamada, M., Blanchard, M.-E., Li, A. Wu, Wall, J.R.

“…Thyroid associated ophthalmopathy (TAO) is an autoimmune disease involving the extra ocular muscles and surrounding orbital connective and adipose tissues. The…”
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Tension-independent heat in rabbit papillary muscle by Alpert, N R, Blanchard, E M, Mulieri, L A

“…1. Heat and force were measured from isometrically contracting (0.2 Hz) rabbit papillary muscles at 21 degrees C during a single contraction-relaxation cycle…”
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Differential Effects of pH on Calcium Activation of Myofilaments of Adult and Perinatal Dog Hearts: Evidence for Developmental Differences in Thin Filament Regulation by Solaro, R John, Kumar, Pankaj, Blanchard, Edward M, Martin, Anne F

“…Our results show that calcium activation of myofilament preparations of dog heart in the perinatal period is unaffected by a reduction in pH from 7.0 to 6.5,…”
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Influence of isoproterenol on myocardial energetics: experimental and clinical investigations by HASENFUSS, G, HOLUBARSCH, C, BLANCHARD, E. M, MULIERI, L. A, ALPERT, N. R, JUST, H

“…The influence of isoproterenol on myocardial performance and energetics was investigated in normal guinea pig myocardium and in patients with normal left…”
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The effect of acidic pH on the ATPase activity and troponin Ca2+ binding of rabbit skeletal myofilaments by Blanchard, E M, Pan, B S, Solaro, R J

“…We compared the effect of reductions in pH from 7.0 to 6.5 and to 6.2 on Mg-ATPase activity and Ca2+ binding of rabbit psoas myofilaments. The amounts of Ca2+…”
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Genetic and non-genetic control of myocardial calcium by ALPERT, N. R, BLANCHARD, E. M, MULIERI, L. A, NAGAI, R, ZARAIN-HERBERG, A, PERIASAMY, M

“…Some aspects of the genetic and non-genetic control of the amount and rate of calcium cycled during steady-state activation of papillary muscles from right…”
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An infrared study of the effects of hydration on cation-loaded nafion thin films by Blanchard, Renée M., Nuzzo, Ralph G.

“…We explore the effects of hydration on the vibrational spectra of cation‐exchanged Nafion thin films. In addition to the initial H+ form of the membrane, the…”
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Myocardial adaptation to stress from the viewpoint of adaptation and development by Hasenfuss, G, Mulieri, L A, Holubarsch, C, Blanchard, E M, Just, H, Alpert, N R

“…Myocardial adaptation to stress and development includes reorganization of subcellular systems. Using a myothermal method, changes in the contractile protein…”
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Dynamic calcium requirements for activation of human ventricular muscle calculated from tension-independent heat by Blanchard, E M, Leavitt, B J, Mulieri, L A, Alpert, N R

“…The heat and tension generated by strips of human left ventricle taken from nonfailing hearts were measured at 30 C before and after partial inhibition of ATP…”
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The effects of acute and chronic inotropic interventions on tension independent heat of rabbit papillary muscle by Blanchard, E M, Mulieri, L A, Alpert, N R

“…We have used the myothermal method to noninvasively monitor the amount of calcium cycled during a single isometric twitch of rabbit papillary muscle…”
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The reorganization of the human and rabbit heart in response to haemodynamic overload by Alpert, N R, Hasenfuss, G, Mulieri, L A, Blanchard, E M, Leavitt, B J, Ittleman, F

“…A myothermal/mechanical analysis on non-failing and failing human hearts and normal and pressure overloaded rabbit hearts is reported. Heat production is…”
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Peripheral blood transcriptomics-based molecular predictors of breast cancer by Blanchard, E. M., Domhan, S., Ma, L., Schwager, C., Ambika, S., Martin, L. A., Debus, J., Hesketh, P. J., Hlatky, L., Abdollahi, A.

“…Abstract only…”
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The epidemiology and spectrum of surgical care in district hospitals of Pakistan by Blanchard, R J, Blanchard, M E, Toussignant, P, Ahmed, M, Smythe, C M

“…On-site surveys of 19 district-level hospitals in Pakistan revealed that, in 1983, 23,839 procedures were performed. There were 98 different types of…”
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Modulation of myothermal economy of isometric force generation by positive inotropic interventions in the guinea pig myocardium by Holubarsch, C H, Hasenfuss, G, Just, H, Blanchard, E M, Mulieri, L A, Alpert, N R

“…Isometric force development has been measured simultaneously with liberated heat in papillary muscles from the right ventricle of the guinea pig, using rapid…”
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Tension independent heat reflects phospholamban regulation of sarcoplasmic reticulum activity in rabbit papillary muscle by Blanchard, E M, Alpert, N R

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