Search Results - "BLANC, Véronique"

Colistin in multi-drug resistant Pseudomonas aeruginosa blood-stream infections A narrative review for the clinician by MARTIS, Nihal, LEROY, Sylvie, BLANC, Véronique

“…Antimicrobial resistance to Pseudomonas aeruginosa is on the rise. In the absence of new anti-pseudomonal drugs, clinicians have had to resort to older…”
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Bedbugs and Infectious Diseases by Delaunay, Pascal, Blanc, Véronique, Del Giudice, Pascal, Levy-Bencheton, Anna, Chosidow, Olivier, Marty, Pierre, Brouqui, Philippe

“…Bedbugs are brown and flat hematophagous insects. The 2 cosmopolite species, Cimex lectularius and Cimex hemipterus, feed on humans and/or domestic animals,…”
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An Antibody–Drug Conjugate Targeting MUC1-Associated Carbohydrate CA6 Shows Promising Antitumor Activities by Nicolazzi, Céline, Caron, Anne, Tellier, Alexia, Trombe, Marc, Pinkas, Jan, Payne, Gillian, Carrez, Chantal, Guérif, Stéphane, Maguin, Marie, Baffa, Raffaele, Fassan, Matteo, Adam, Julien, Mangatal-Wade, Lydie, Blanc, Véronique

“…Abstract Glycosylation is a complex multienzyme-related process that is frequently deregulated in cancer. Aberrant glycosylation can lead to the generation of…”
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Antibody-drug conjugate (ADC) clinical pipeline: a review by Sassoon, Ingrid, Blanc, Véronique

“…Biological therapies play an increasing role in cancer treatment, although the number of naked antibodies showing clinical efficacy as single agent remains…”
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Antibiotic therapy for Enterococcus bacteraemia: warning for the antimicrobial stewardship team by Souhail, Bérénice, Le Maréchal, Marion, Manuello, Roxane, Chrétien, Ratana, Charlot, Patrick, Déroudilhes, Gilles, Della Guardia, Marc, Blanc, Véronique, Fribourg, Agnès, Degand, Nicolas, Roger, Pierre-Marie

“…Enterococci are a significant cause of bacteraemia in healthcare-associated infections (HCAI), being resistant to cephalosporins and aminoglycosides often used…”
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Biopharmaceutical Assessment of Dexamethasone Acetate-Based Hydrogels Combining Hydroxypropyl Cyclodextrins and Polysaccharides for Ocular Delivery by Mazet, Roseline, García-Otero, Xurxo, Choisnard, Luc, Wouessidjewe, Denis, Verdoot, Vincent, Bossard, Frédéric, Díaz-Tomé, Victoria, Blanc-Marquis, Véronique, Otero-Espinar, Francisco-Javier, Fernandez-Ferreiro, Anxo, Gèze, Annabelle

“…We previously developed two optimized formulations of dexamethasone acetate (DXMa) hydrogels by means of special cubic mixture designs for topical ocular…”
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Colistin in multi-drug resistant Pseudomonas aeruginosa blood-stream infections by Martis, Nihal, Leroy, Sylvie, Blanc, Véronique

“…Summary Antimicrobial resistance to Pseudomonas aeruginosa is on the rise. In the absence of new anti-pseudomonal drugs, clinicians have had to resort to older…”
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Combination of obstructive sleep apnoea and insomnia treated by continuous positive airway pressure with the SensAwake pressure relief technology to assist sleep: a randomised cross-over trial protocol by Pepin, Jean Louis, Gagnadoux, Frédéric, Foote, Alison, Vicars, Rachel, Ogra, Bhavi, Viot-Blanc, Véronique, Benmerad, Meriem, D’Ortho, Marie-Pia, Tamisier, Renaud

“…IntroductionObstructive sleep apnoea (OSA) is a common sleep breathing disorder affecting up to 17% of the middle-aged population. Continuous positive airway…”
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Primary skin abscesses are mainly caused by Panton-Valentine leukocidin-positive Staphylococcus aureus strains by del Giudice, Pascal, Blanc, Véronique, de Rougemont, Alexis, Bes, Michèle, Lina, Gérard, Hubiche, Thomas, Roudière, Laurent, Vandenesch, François, Etienne, Jérôme

“…The role of Panton-Valentine leukocidin (PVL) in skin and soft-tissue infections is not clear. Our purpose was to determine the prevalence of PVL gene carriage…”
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SAR650984, A Novel Humanized CD38-Targeting Antibody, Demonstrates Potent Antitumor Activity in Models of Multiple Myeloma and Other CD38+ Hematologic Malignancies by DECKERT, Jutta, WETZEL, Marie-Cécile, DUMONTET, Charles, PLESA, Adriana, CHIRON, Marielle, LEJEUNE, Pascale, CHITTENDEN, Thomas, PARK, Peter U, BLANC, Véronique, BARTLE, Laura M, SKALETSKAYA, Anna, GOLDMACHER, Victor S, VALLEE, François, QING, Zhou-Liu, FERRARI, Paul, POUZIEUX, Stéphanie, LAHOUTE, Charlotte

“…The CD38 cell surface antigen is expressed in diverse hematologic malignancies including multiple myeloma, B-cell non-Hodgkin lymphoma (NHL), B-cell chronic…”
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Panton-Valentine leukocidin-positive Staphylococcus aureus strains are associated with follicular skin infections by Del Giudice, Pascal, Bes, Michèle, Hubiche, Thomas, Blanc, Véronique, Roudière, Laurent, Lina, Gérard, Vandenesch, François, Etienne, Jérôme

“…Panton-Valentine leukocidin (PVL)-positive Staphylococcus aureus have been associated with suppurative infections; however, their precise role in skin…”
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The Crystal Structures of Four Peptide Deformylases Bound to the Antibiotic Actinonin Reveal Two Distinct Types: A Platform for the Structure-based Design of Antibacterial Agents by Guilloteau, Jean-Pierre, Mathieu, Magali, Giglione, Carmela, Blanc, Véronique, Dupuy, Alain, Chevrier, Miline, Gil, Patricia, Famechon, Alain, Meinnel, Thierry, Mikol, Vincent

“…Bacterial peptide deformylase (PDF) belongs to a sub-family of metalloproteases that catalyse the removal of the N-terminal formyl group from newly synthesised…”
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Metabolic Profiling Reveals a Contribution of Gut Microbiota to Fatty Liver Phenotype in Insulin-Resistant Mice by Dumas, Marc-Emmanuel, Barton, Richard H., Toye, Ayo, Cloarec, Olivier, Blancher, Christine, Rothwell, Alice, Fearnside, Jane, Tatoud, Roger, Blanc, Véronique, Lindon, John C., Mitchell, Steve C., Holmes, Elaine, McCarthy, Mark I., Scott, James, Gauguier, Dominique, Nicholson, Jeremy K.

“…Here, we study the intricate relationship between gut microbiota and host cometabolic phenotypes associated with dietary-induced impaired glucose homeostasis…”
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Sleep apnea and glucose metabolism: The new challenge by Viot-Blanc, Véronique, Lévy, Patrick

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In silico and pharmacological evaluation of GPR65 as a cancer immunotherapy target regulating T-cell functions by Li, Shamin, Melchiore, Fabien, Kantari-Mimoun, Chahrazade, Mouton, Aurore, Knockaert, Samantha, Philippon, Wendy, Chanrion, Benjamin, Bourgeois, Christophe, Lefebvre, Céline, Elhmouzi-Younes, Jamila, Blanc, Véronique, Ramon Olayo, Fernando, Laugel, Bruno

“…The success of cancer immunotherapies such as immune checkpoint inhibitors, CAR T-cells and immune cell engagers have provided clinicians with tools to bypass…”
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SAR3419: an anti-CD19-Maytansinoid Immunoconjugate for the treatment of B-cell malignancies by Blanc, Veronique, Bousseau, Anne, Caron, Anne, Carrez, Chantal, Lutz, Robert J, Lambert, John M

“…SAR3419 is a novel anti-CD19 humanized monoclonal antibody conjugated to a maytansine derivate through a cleavable linker for the treatment of B-cell…”
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Preclinical Activity of SAR408701: A Novel Anti-CEACAM5-maytansinoid Antibody-drug Conjugate for the Treatment of CEACAM5-positive Epithelial Tumors by Decary, Stéphanie, Berne, Pierre-François, Nicolazzi, Céline, Lefebvre, Anne-Marie, Dabdoubi, Tarik, Cameron, Béatrice, Rival, Pierrick, Devaud, Catherine, Prades, Catherine, Bouchard, Hervé, Cassé, Alhassan, Henry, Christophe, Amara, Céline, Brillac, Claire, Ferrari, Paul, Maçon, Laetitia, Lacoste, Eric, Combeau, Cecile, Beys, Eric, Naimi, Souad, García-Echeverría, Carlos, Mayaux, Jean-François, Blanc, Véronique

“…Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is a glycoprotein that has limited expression in normal adult tissues, but is overexpressed…”
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Characterization of CD4 + and CD8 + T cells responses in the mixed lymphocyte reaction by flow cytometry and single cell RNA sequencing by Mangelinck, Adèle, Dubuisson, Agathe, Becht, Etienne, Dromaint-Catesson, Sandra, Fasquel, Manon, Provost, Nicolas, Walas, Dawid, Darville, Hélène, Galizzi, Jean-Pierre, Lefebvre, Céline, Blanc, Véronique, Lombardi, Vincent

“…The Mixed Lymphocyte Reaction (MLR) consists in the allogeneic co-culture of monocytes derived dendritic cells (MoDCs) with T cells from another donor. This…”
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SAR650984: A Potent Anti-CD38 Therapeutic Antibody with Three Mechanisms of Action (Apoptosis, ADCC, CDC) for Hematological Malignancies by Park, Peter U., Blanc, Véronique, Deckert, Jutta, Lejeune, Pascale, Bartle, Laura M., Skaletskaya, Anna, Mayo, Michele F., Zhang, Chonghui, Wetzel, Marie-Cécile, Tavares, Daniel J., Lutz, Robert J., Chittenden, Thomas, Bissery, Marie-Christine, Lambert, John M., Goldmacher, Victor S.

“…CD38 is a promising target for antibody therapeutics for the treatment of various hematological malignancies, including multiple myeloma as well as…”
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Systemic immune‐checkpoint blockade with anti‐PD1 antibodies does not alter cerebral amyloid‐β burden in several amyloid transgenic mouse models by Latta‐Mahieu, Martine, Elmer, Bradford, Bretteville, Alexis, Wang, Yaming, Lopez‐Grancha, Mati, Goniot, Philippe, Moindrot, Nicolas, Ferrari, Paul, Blanc, Véronique, Schussler, Nathalie, Brault, Emmanuel, Roudières, Valérie, Blanchard, Véronique, Yang, Zhi‐Yong, Barneoud, Pascal, Bertrand, Philippe, Roucourt, Bart, Carmans, Sofie, Bottelbergs, Astrid, Mertens, Liesbeth, Wintmolders, Cindy, Larsen, Peter, Hersley, Caroline, McGathey, Tyler, Racke, Margaret M., Liu, Ling, Lu, Jirong, O'Neill, Michael J., Riddell, David R., Ebneth, Andreas, Nabel, Gary J., Pradier, Laurent

“…Chronic inflammation represents a central component in the pathogenesis of Alzheimer's disease (AD). Recent work suggests that breaking immune tolerance by…”
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