Search Results - "BLAKE, M. C"

A Meta-Analysis of CYP2D6 Metabolizer Phenotype and Metoprolol Pharmacokinetics by Blake, C M, Kharasch, E D, Schwab, M, Nagele, P

“…Metoprolol, a commonly prescribed β‐blocker, is primarily metabolized by cytochrome P450 2D6 (CYP2D6), an enzyme with substantial genetic heterogeneity…”
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Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivo by BLAKE, M. C, AZIZKHAN, J. C

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Transcriptional initiation is controlled by upstream GC-box interactions in a TATAA-less promoter by BLAKE, M. C, JAMBOU, R. C, SWICK, A. G, KAHN, J. W, AZIZKHAN, J. C

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From Goose Drops to Spec Ops: A Pinfire Shotgun Shell from Fort York by Williams, Blake C. M.

“…In 2011, during a salvage excavation at the Fort York National Historic Site, Archaeological Services Inc. (ASI) recovered a pinfire shotgun shell cartridge…”
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Atypical scrapie cases in the UK by Konold, T., Davis, A., Bone, G. E., Simmons, M. M., Kahn, J., Blake-Dyke, M. C., Bracegirdle, J., Shimwell, C. J.

“…All clinical cases presented with ataxia without evidence of pruritus or wool loss. [...]August 2005, atypical cases in Great Britain were only identified…”
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Evidence of a molecular clock in the ovine ovary and the influence of photoperiod by Murphy, B.A., Blake, C.M., Brown, J.A., Martin, A.-M., Forde, N., Sweeney, L.M., Evans, A.C.O.

“…The influence of the central circadian clock on reproductive timing is well established. Much less is known about the role of peripheral oscillators such as…”
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The yeast Cln3 protein is an unstable activator of Cdc28 by CROSS, F. R, BLAKE, C. M

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Gonococcal opacity: lectin-like interactions between Opa proteins and lipooligosaccharide by BLAKE, M. S, BLAKE, C. M, APICELLA, M. A, MANDRELL, R. E

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Biostratigraphic Constraints on Formation and Timing of Accretion in a Subduction Complex: An Example from the Franciscan Complex of Northern California by Isozaki, Y., Blake, M. C.

“…The determination of the total age coverage of pelagic bedded chert is particularly important in studies of ancient accretionary complexes because the time…”
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Global access to surgical care: a modelling study by Alkire, Blake C, MD, Raykar, Nakul P, Dr, Shrime, Mark G, MD, Weiser, Thomas G, MD, Bickler, Stephen W, Prof, Rose, John A, MD, Nutt, Cameron T, BA, Greenberg, Sarah L M, MD, Kotagal, Meera, MD, Riesel, Johanna N, MD, Esquivel, Micaela, MD, Uribe-Leitz, Tarsicio, MD, Molina, George, MD, Roy, Nobhojit, Prof, Meara, John G, MD, Farmer, Paul E, Prof

“…Summary Background More than 2 billion people are unable to receive surgical care based on operating theatre density alone. The vision of the Lancet Commission…”
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Catastrophic expenditure to pay for surgery worldwide: a modelling study by Shrime, Mark G, Dr, Dare, Anna J, MBChB, Alkire, Blake C, MD, O'Neill, Kathleen, BS, Meara, John G, MD

“…Summary Background Approximately 150 million individuals worldwide face catastrophic expenditure each year from medical costs alone, and the non-medical costs…”
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Time of day influences cytokine and clock gene response to immune stimulation in equine whole blood by McGlynn, O.F, Browne, J.A, Blake, C.M, Murphy, B.A

“…The immune system demonstrates regularly recurring rhythmic variation that has important medical and veterinary clinical implications. Emerging evidence…”
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Regulation of Plasminogen Activator Inhibitor-1 Expression by Transforming Growth Factor-β-induced Physical and Functional Interactions between Smads and Sp1 by Datta, Pran K., Blake, Michael C., Moses, Harold L.

“…Members of the transforming growth factor-β (TGF-β) superfamily mediate a broad range of biological activities by regulating the expression of target genes…”
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Structure and Metamorphism of the Franciscan Complex, Mt. Hamilton Area, Northern California by Blake, M. C., Wentworth, C. M.

“…Truncation of metamorphic isograds and fold axes within coherent terranes of Franciscan meta-graywacke by intervening zones of melange indicate that the…”
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Isolation and characterization of mutants with lesions affecting pellicle formation and erythrocyte agglutination by type 1 piliated Escherichia coli by HARRIS, S. L, ELLIOTT, D. A, BLAKE, M. C, MUST, L. M, MESSENGER, M, ORNDORFF, P. E

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Franciscan Complex Calera limestones: accreted remnants of Farallon Plate oceanic plateaus by Tarduno, John A, McWilliams, Michael, Debiche, Michel G, Sliter, William V, Blake, M. C

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Southern Hemisphere Origin of the Cretaceous Laytonville Limestone of California by Tarduno, J. A., McWilliams, M., Sliter, W. V., Cook, H. E., Blake, M. C., Premoli-Silva, I.

“…New paleomagnetic, paleontologic, and stratigraphie data from outcrops of the Laytonville Limestone (101 to 88 million years old) support a Southern Hemisphere…”
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Timing and cost of scaling up surgical services in low-income and middle-income countries from 2012 to 2030: a modelling study by Verguet, Stéphane, Dr, Alkire, Blake C, MD, Bickler, Stephen W, MD, Lauer, Jeremy A, PhD, Uribe-Leitz, Tarsicio, MD, Molina, George, MD, Weiser, Thomas G, MD, Yamey, Gavin, MD, Shrime, Mark G, MD

“…Summary Background Given the large burden of surgical conditions and the crosscutting nature of surgery, scale-up of basic surgical services is crucial to…”
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Functional analysis of GC element binding and transcription in the hamster dihydrofolate reductase gene promoter by Swick, A G, Blake, M C, Kahn, J W, Azizkhan, J C

“…Dihydrofolate reductase (DHFR) gene expression is required for cell growth. The DHFR gene promoter contains several GC elements capable of binding the…”
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Opportunistic salpingectomy: uptake, risks, and complications of a regional initiative for ovarian cancer prevention by McAlpine, Jessica N., MD, Hanley, Gillian E., MA, PhD, Woo, Michelle M.M., PhD, Tone, Alicia A., PhD, Rozenberg, Nirit, Swenerton, Kenneth D., MD, Gilks, C. Blake, MD, Finlayson, Sarah J., MD, Huntsman, David G., MD, Miller, Dianne M., MD

“…Objective The purpose of this study was to assess the uptake and perioperative safety of bilateral salpingectomy (BS) as an ovarian cancer risk-reduction…”
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