Search Results - "BLAIR, Brian"

Extending end‐of‐summer‐snowlines for the Southern Alps glaciers of New Zealand back to 1949 by Salinger, Michael James, Fitzharris, Brian Blair, Chinn, Trevor

“…New Zealand has a more than four‐decade long (1977–2019) continuous record of measurements of the altitude of end‐of‐summer‐snowlines (EOSS). These are…”
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Detection of Cancer DNA in Plasma of Patients with Early-Stage Breast Cancer by BEAVER, Julia A, JELOVAC, Danijela, CHU, David, BURNS, Timothy, HIGGINS, Michaela J, STEARNS, Vered, JACOBS, Lisa, HABIBI, Mehran, LANGE, Julie, HURLEY, Paula J, LAURING, Josh, VANDENBERG, Dustin A, BALUKRISHNA, Sasidharan, KESSLER, Jill, JETER, Stacie, SAMUELS, Michael L, MAAR, Dianna, COPE, Leslie, CIMINO-MATHEWS, Ashley, ARGANI, Pedram, WOLFF, Antonio C, BEN HO PARK, COCHRAN, Rory L, CROESSMANN, Sarah, ZABRANSKY, Daniel J, HONG YUEN WONG, TORO, Patricia Valda, CIDADO, Justin, BLAIR, Brian G

“…Detecting circulating plasma tumor DNA (ptDNA) in patients with early-stage cancer has the potential to change how oncologists recommend systemic therapies for…”
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Copper Transporter 2 Regulates the Cellular Accumulation and Cytotoxicity of Cisplatin and Carboplatin by BLAIR, Brian G, LARSON, ChristopherA, SAFAEI, Roohangiz, HOWELL, Stephen B

“…Purpose: Copper transporter 2 (CTR2) is known to mediate the uptake of Cu +1 by mammalian cells. Several other Cu transporters, including the influx…”
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Somatic alterations as the basis for resistance to targeted therapies by Blair, Brian G, Bardelli, Alberto, Park, Ben Ho

“…Recent advances in genetics and genomics have revealed new genes and pathways that are somatically altered in human malignancies. This wealth of knowledge has…”
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The role of the mammalian copper transporter 1 in the cellular accumulation of platinum-based drugs by Larson, Christopher A, Blair, Brian G, Safaei, Roohangiz, Howell, Stephen B

“…The mammalian copper transporter 1 (CTR1) is responsible for the uptake of copper from the extracellular space. In this study, we used an isogenic pair of…”
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Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood by HIGGINS, Michaela J, JELOVAC, Danijela, EMENS, Leisha, RILEY, Carol, STEARNS, Vered, DIEHL, Frank, ANGENENDT, Philipp, PENG HUANG, COPE, Leslie, ARGANI, Pedram, MURPHY, Kathleen M, BACHMAN, Kurtis E, BARNATHAN, Evan, GRESHOCK, Joel, WOLFF, Antonio C, PARK, Ben H, BLAIR, Brian, SLATER, Shannon, POWERS, Penny, ZORZI, Jane, JETER, Stacie C, OLIVER, George R, FETTING, John

“…We sought to evaluate the feasibility of detecting PIK3CA mutations in circulating tumor DNA (ctDNA) from plasma of patients with metastatic breast cancer…”
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Coadministration of rTMS and Nasal Ketamine on patients with MDD – A Retrospective Study by Caussat, Thomas, Scharf, Gabriel, Blair, Brian, Katyal, Shalini, Oberman, Lindsay M.

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MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers by Mohseni, Morassa, Cidado, Justin, Croessmann, Sarah, Cravero, Karen, Cimino-Mathews, Ashley, Wong, Hong Yuen, Scharpf, Rob, Zabransky, Daniel J, Abukhdeir, Abde M, Garay, Joseph P, Wang, Grace M, Beaver, Julia A, Cochran, Rory L, Blair, Brian G, Rosen, D Marc, Erlanger, Bracha, Argani, Pedram, Hurley, Paula J, Lauring, Josh, Park, Ben Ho

“…Tamoxifen is effective for treating estrogen receptor-alpha (ER) positive breast cancers. However, few molecular mediators of tamoxifen resistance have been…”
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The PIK3CA gene is mutated with high frequency in human breast cancers by Bachman, Kurtis E., Argani, Pedram, Samuels, Yardena, Silliman, Natalie, Ptak, Janine, Szabo, Steve, Konishi, Hiroyuki, Karakas, Bedri, Blair, Brian G., Lin, Clarence, Peters, Brock A., Velculescu, Victor E., Park, Ben Ho

“…The phosphatidylinositol 3-kinases (PI3Ks) are known regulators of cellular growth and proliferation. It has recently been reported that somatic mutations…”
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Longitudinal Rupture of Distal Corpus Cavernosum With Concomitant Urethral Injury: An Uncommon Result of a Common Mechanism by Blair, Brian M., Vilson, Fernandino, Kocher, Neil J., Kloniecke, Edward, Clark, Joseph Y.

“…Fracture of the penis is a well-recognized yet relatively uncommon urologic event. Forceful, blunt trauma with lateral bending of the penis in an erect state…”
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Effects of the loss of Atox1 on the cellular pharmacology of cisplatin by Safaei, Roohangiz, Maktabi, Mohammad H., Blair, Brian G., Larson, Christopher A., Howell, Stephen B.

“…Previous work has demonstrated that the copper (Cu) transporters Ctr1, Atp7a and Atp7b regulate the cellular pharmacology of cisplatin (CDDP) by mediating its…”
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Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo by Blair, Brian G, Larson, Christopher A, Adams, Preston L, Abada, Paolo B, Pesce, Catherine E, Safaei, Roohangiz, Howell, Stephen B

“…Copper transporter 2 (CTR2) is one of the four copper transporters in mammalian cells that influence the cellular pharmacology of cisplatin and carboplatin…”
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The role of the N-terminus of mammalian copper transporter 1 in the cellular accumulation of cisplatin by Larson, Christopher A., Adams, Preston L., Jandial, Danielle D., Blair, Brian G., Safaei, Roohangiz, Howell, Stephen B.

“…The mammalian copper transporter 1 (CTR1) is responsible for the uptake of copper (Cu) from the extracellular space, and has been shown to play a major role in…”
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Sodium Polystyrene Sulfonate-Induced Gastric Pneumatosis: A Rare Side Effect by Dasu, Neethi, Khalid, Yaser, Dasu, Kirti, Joo, Lucy, Blair, Brian

“…Abstract Kayexalate has been used in the USA since 1975 for the treatment of hyperkalemia. Prior case reports have shown that sorbitol added to kayexalate has…”
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Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation by WANG, Grace M, YUEN WONG, Hong, GARAY, Joseph P, MOHSENI, Morassa, HIGGINS, Michaela J, CIDADO, Justin, JELOVAC, Danijela, CROESSMANN, Sarah, COCHRAN, Rory L, KARNAN, Sivasundaram, KONISHI, Yuko, OTA, Akinobu, KONISHI, Hiroyuki, HOSOKAWA, Yoshitaka, ARGANI, Pedram, LAURING, Josh, HO PARK, Ben, BLAIR, Brian G, ABUKHDEIR, Abde M, GUSTIN, John P, MARC ROSEN, D, RAY DENMEADE, Samuel, RASHEED, Zeshaan, MATSUI, William

“…The selective pressures leading to cancers with mutations in both KRAS and PIK3CA are unclear. Here, we show that somatic cell knockin of both KRAS G12V and…”
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An Unfortunate Cause of Chronic Nausea and Vomiting: Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE) by Dasu, Neethi, Blair, Brian, Foster, C. Jonathan, Smith, Colin

“…We present a unique case of a 24-year-old male who was admitted for intractable nausea, emesis, weight loss, and abdominal discomfort. The patient underwent an…”
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The role of the methionines and histidines in the transmembrane domain of mammalian copper transporter 1 in the cellular accumulation of cisplatin by Larson, Christopher A, Adams, Preston L, Blair, Brian G, Safaei, Roohangiz, Howell, Stephen B

“…Mammalian copper transporter 1 (CTR1) is a high-affinity copper influx transporter that also mediates the uptake of platinum-containing chemotherapeutic agents…”
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Regulation of copper transporter 2 expression by copper and cisplatin in human ovarian carcinoma cells by Blair, Brian G, Larson, Christopher A, Adams, Preston L, Abada, Paolo B, Safaei, Roohangiz, Howell, Stephen B

“…Down-regulation of copper transporter 1 (CTR1) reduces uptake and sensitivity, whereas down-regulation of CTR2 enhances both. Cisplatin (DDP) triggers the…”
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Predicted versus observed 30-day perioperative outcomes using the ACS NSQIP surgical risk calculator in patients undergoing partial nephrectomy for renal cell carcinoma by Blair, Brian M., Lehman, Erik B., Jafri, Syed M., Kaag, Matthew G., Raman, Jay D.

“…Purpose The purpose of the study was to evaluate the accuracy of the American College of Surgeons NSQIP Surgical Risk Calculator for predicting risk-adjusted…”
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In-Hospital Outcomes of Patients With Pulmonary Hypertension and Cirrhosis: A 6-Year Population Cohort Study of Over One Million Patients by Khalid, Yaser, Dasu, Neethi, Zafar, Raja Fawad, Suga, Herman, Dasu, Kirti, Blair, Brian

“…Introduction There is a paucity of data on the influence of sex, race, insurance, pulmonary hypertension-related complications, and cirrhosis-related…”
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