Search Results - "BLACKWOOD, E. M"

Going the Distance: A Current View of Enhancer Action by Blackwood, Elizabeth M., Kadonaga, James T.

“…In eukaryotes, transcription of genes by RNA polymerase II yields messenger RNA intermediates from which protein products are synthesized. Transcriptional…”
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Phase I study of the checkpoint kinase 1 inhibitor GDC-0575 in combination with gemcitabine in patients with refractory solid tumors by Italiano, A., Infante, J.R., Shapiro, G.I., Moore, K.N., LoRusso, P.M., Hamilton, E., Cousin, S., Toulmonde, M., Postel-Vinay, S., Tolaney, S., Blackwood, E.M., Mahrus, S., Peale, F.V., Lu, X., Moein, A., Epler, J., DuPree, K., Tagen, M., Murray, E.R., Schutzman, J.L., Lauchle, J.O., Hollebecque, A., Soria, J.-C.

“…Checkpoint kinase 1 (Chk1) inhibition following chemotherapy-elicited DNA damage overrides cell cycle arrest and induces mitotic catastrophe and cell death…”
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Myc and Max associate in vivo by BLACKWOOD, E. M, LÜSCHER, B, EISENMAN, R. N

“…Max is a helix-loop-helix zipper protein that associates in vitro with Myc family proteins to form a sequence-specific DNA-binding complex. We show here, by…”
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Myc and Max proteins possess distinct transcriptional activities by Kretzner, Leo, Blackwood, Elizabeth M, Eisenman, Robert N

“…The Myc family proteins are thought to be involved in transcription because they have both a carboxy-terminal basic-helix-loop-helix-zipper (bHLH-Z) domain,…”
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Sequence-Specific DNA Binding by the c-Myc Protein by Blackwell, T. Keith, Kretzner, Leo, Blackwood, Elizabeth M., Eisenman, Robert N., Weintraub, Harold

“…While it has been known for some time that the c-Myc protein binds to random DNA sequences, no sequence-specific binding activity has been detected. At its…”
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Alternative Modes of Substrate Distortion in Enzyme and Antibody Catalyzed Ferrochelation Reactions by Blackwood, Milton E, Rush, Thomas S, Romesberg, Floyd, Schultz, Peter G, Spiro, Thomas G

“…Both an antibody that catalyzes metal insertion into porphyrins and the corresponding enzyme, ferrochelatase, are shown by resonance Raman spectroscopy to…”
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Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc by Blackwood, Elizabeth M., Eisenman, Robert N.

“…The myc protooncogene family has been implicated in cell proliferation, differentiation, and neoplasia, but its mechanism of function at the molecular level is…”
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The Myc:Max protein complex and cell growth regulation by Blackwood, E M, Lüscher, B, Kretzner, L, Eisenman, R N

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Selective enhancement of resonance Raman spectra of separate bacteriopheophytins in Rb. sphaeroides reaction centers by Eads, Daniel D., Moser, Chris, Blackwood Jr, Milton E., Lin, Ching-Yao, Dutton, Leslie, Spiro, Thomas G.

“…Tunable dye laser excitation of carefully prepared samples of Rb. sphaeroides reaction centers provides richly detailed resonance Raman (RR) spectra of the…”
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Regulation of Myc: Max Complex Formation and Its Potential Role in Cell Proliferation by BLAOKWOOD, ELIZABETH M., EISENMAN, ROBERT N.

“…BLACKWOOD, E.M. and EISENMAN, R.N. Regulation of Myc: Max Complex Formation and Its Potential Role in Cell Proliferation. Tohoku J. Exp. Med., 1992, 168 (2),…”
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Transcriptional activities of the Myc and Max proteins in mammalian cells by Kretzner, L, Blackwood, E M, Eisenman, R N

“…The myc family of oncogenes exhibit deregulated expression in a host of neoplasias. Though the molecular function of the Myc protein in both normal and…”
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Expression of two distinct homologues of Xenopus Max during early development by KING, M. W, BLACKWOOD, E. M, EISENMAN, R. N

“…The Max protein belongs to the basic region-helix-loop-helix-leucine zipper family of transcriptional regulators. Max heterodimerizes with Myc family proteins…”
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Resonance Raman spectroelectrochemistry of the C60 radical anion by MCGLASHEN, M. L, BLACKWOOD, M. E, SPIRO, T. G

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Functional analysis of the AUG- and CUG-initiated forms of the c-Myc protein by Blackwood, E M, Lugo, T G, Kretzner, L, King, M W, Street, A J, Witte, O N, Eisenman, R N

“…Activation of the c-myc proto-oncogene by chromosomal translocation or proviral insertion frequently results in the separation of the c-myc coding region from…”
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Mapping of MAX to human chromosome 14 and mouse chromosome 12 by in situ hybridization by Gilladoga, A D, Edelhoff, S, Blackwood, E M, Eisenman, R N, Disteche, C M

“…The protein encoded by the MAX gene is a member of the class of basic region-helix-loop-helix-zipper proteins and has been demonstrated to associate with N-,…”
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Resonance Raman characterization of the triplet state of zinc tetraphenylchlorin by Vitols, S. E, Terashita, Shin-ichi, Blackwood, Milton E, Kumble, Ranjit, Ozaki, Yukihiro, Spiro, Thomas G

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Myc and Max function as a nucleoprotein complex by Blackwood, E M, Kretzner, L, Eisenman, R N

“…The Myc family of oncoproteins are thought to regulate proliferation and differentiation in a wide variety of cell types. Recent studies show that Myc proteins…”
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Identification of protein-protein interactions by lambda gt11 expression cloning by Blackwood, E M, Eisenman, R N

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Resonance Raman Spectra of Ferrochelatase Reveal Porphyrin Distortion upon Metal Binding by Blackwood, Milton E, Rush, Thomas S, Medlock, Amy, Dailey, Harry A, Spiro, Thomas G

“…Ferrochelatase catalyzes Fe2+ insertion into porphyrins, and is inhibited by Hg2+. Resonance Raman spectra of mesoporphyrin IX show that binding to…”
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Simulation of Non-Condon Enhancement and Interference Effects in the Resonance Raman Intensities of Metalloporphyrins by Kumble, Ranjit, Rush, Thomas S, Blackwood, Milton E, Kozlowski, Pawel M, Spiro, Thomas G

“…The room-temperature resonance Raman (RR) spectra of nickel(II) porphine have been simulated for excitation within the Q-band optical transition, taking into…”
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