Search Results - "BLACKNEY, Michael"
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Cloning and expression analysis of Drosophila extracellular Cu Zn superoxide dismutase
Published in Bioscience reports (01-01-2014)“…In the present study, we cloned and sequenced the mRNAs of the Sod3 [extracellular Cu Zn SOD (superoxide dismutase)] gene in Drosophila and identified two mRNA…”
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Economic impact of treating invasive mold disease with isavuconazole compared with liposomal amphotericin B in the UK
Published in Future microbiology (01-09-2018)“…Invasive mold diseases (IMDs) are associated with significant morbidity and mortality. Approved treatments include voriconazole (VORI), liposomal amphotericin…”
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The cost of treating mucormycosis with isavuconazole compared with standard therapy in the UK
Published in Future microbiology (01-05-2017)“…Mucormycosis is a fungal infection associated with high mortality. Until recently, the only licensed treatments were amphotericin B (AMB) formulations…”
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Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosis
Published in Journal of medicinal chemistry (25-02-2010)“…FIXa is a serine protease enzyme involved in the intrinsic pathway of the coagulation cascade. The upstream intervention of the coagulation cascade in…”
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Structure Based Drug Design: Development of Potent and Selective Factor IXa (FIXa) Inhibitors
Published in Journal of medicinal chemistry (25-02-2010)“…On the basis of our understanding on the binding interactions of the benzothiophene template within the FIXa active site by X-ray crystallography and molecular…”
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Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosist
Published in Journal of medicinal chemistry (2010)Get full text
Journal Article -
7
Characterising the drosophila extracellular superoxide dismutase gene
Published 01-01-2010“…The indiscriminate action of reactive oxygen species (ROS), if left unregulated, has long been considered contributory to a range of disease processes within…”
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Dissertation