Search Results - "BJELIK, Annamaria"

A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging by Kovács, Tibor, Szinyákovics, Janka, Billes, Viktor, Murányi, Gábor, Varga, Virginia B., Bjelik, Annamária, Légrádi, Ádám, Szabó, Melinda, Sándor, Sára, Kubinyi, Enikő, Szekeres-Paracky, Cecília, Szocsics, Péter, Lőke, János, Mulder, Jun, Gulyás, Balázs, Renner, Éva, Palkovits, Miklós, Gulya, Károly, Maglóczky, Zsófia, Vellai, Tibor

“…Ageing is driven by the progressive, lifelong accumulation of cellular damage. Autophagy (cellular self-eating) functions as a major cell clearance mechanism…”
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The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms by Kovács, Tibor, Billes, Viktor, Komlós, Marcell, Hotzi, Bernadette, Manzéger, Anna, Tarnóci, Anna, Papp, Diána, Szikszai, Fanni, Szinyákovics, Janka, Rácz, Ákos, Noszál, Béla, Veszelka, Szilvia, Walter, Fruzsina R., Deli, Mária A., Hackler, Laszlo, Alfoldi, Robert, Huzian, Orsolya, Puskas, Laszlo G., Liliom, Hanna, Tárnok, Krisztián, Schlett, Katalin, Borsy, Adrienn, Welker, Ervin, Kovács, Attila L., Pádár, Zsolt, Erdős, Attila, Legradi, Adam, Bjelik, Annamaria, Gulya, Károly, Gulyás, Balázs, Vellai, Tibor

“…Autophagy functions as a main route for the degradation of superfluous and damaged constituents of the cytoplasm. Defects in autophagy are implicated in the…”
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Capsaicin promotes the amyloidogenic route of brain amyloid precursor protein processing by Pákáski, Magdolna, Hugyecz, Marietta, Sántha, Péter, Jancsó, Gábor, Bjelik, Annamária, Domokos, Ágnes, Janka, Zoltán, Kálmán, János

“…Besides being an important component of spices used worldwide, capsaicin has wide-ranging therapeutic potential as a hypolipidemic, antioxidant and…”
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Imipramine and citalopram facilitate amyloid precursor protein secretion in vitro by Pákáski, Magdolna, Bjelik, Annamária, Hugyecz, Marietta, Kása, Péter, Janka, Zoltán, Kálmán, János

“…Comorbid depression of Alzheimer's disease (AD) is a common mood disorder in the elderly and a broad spectrum of antidepressants have been used for its…”
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Age-dependent oxidative stress-induced DNA damage in Down’s lymphocytes by Zana, Marianna, Szécsényi, Anita, Czibula, Ágnes, Bjelik, Annamária, Juhász, Anna, Rimanóczy, Ágnes, Szabó, Krisztina, Vetró, Ágnes, Szűcs, Péter, Várkonyi, Ágnes, Pákáski, Magdolna, Boda, Krisztina, Raskó, István, Janka, Zoltán, Kálmán, János

“…The aim of the present study was to investigate the oxidative status of lymphocytes from children ( n = 7) and adults ( n = 18) with Down’s syndrome (DS). The…”
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Human apoB overexpression and a high-cholesterol diet differently modify the brain APP metabolism in the transgenic mouse model of atherosclerosis by Bjelik, Annamária, Bereczki, Erika, Gonda, Szilvia, Juhász, Anna, Rimanóczy, Ágnes, Zana, Marianna, Csont, Tamás, Pákáski, Magdolna, Boda, Krisztina, Ferdinandy, Péter, Dux, László, Janka, Zoltán, Sántha, Miklós, Kálmán, János

“…Epidemiological and biochemical data suggest a link between the cholesterol metabolism, the amyloid precursor protein (APP) processing and the increased…”
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Effect of general anesthetics on amyloid precursor protein and mRNA levels in the rat brain by Palotás, Miklós, Palotás, András, Bjelik, Annamária, Pákáski, Magdolna, Hugyecz, Marietta, Janka, Zoltán, Kálmán, János

“…The incidence of Alzheimer's disease is elevated after exposure to surgical interventions. Since amyloid precursor protein (APP) and its neurotoxic derivatives…”
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APP mRNA splicing is upregulated in the brain of biglycan transgenic mice by Bjelik, Annamária, Pákáski, Magdolna, Bereczki, Erika, Gonda, Szilvia, Juhász, Anna, Rimanóczy, Ágnes, Zana, Marianna, Janka, Zoltán, Sántha, Miklós, Kálmán, János

“…Many of the risk factors for cerebrovascular disease and atherosclerosis also increase the risk of Alzheimer's disease, characterized by the cerebral…”
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3,4-Methylenedioxymethamphetamine (MDMA), but not morphine, alters APP processing in the rat brain by Kálmán, János, Bjelik, Annamária, Hugyecz, Marietta, Tímár, Júlia, Gyarmati, Zsuzsanna, Zana, Marianna, Fürst, Zsuzsanna, Janka, Zoltán, Rakonczay, Zoltán, Horváth, Zoltán, Pákáski, Magdolna

“…The abuse of drugs such as opioids and 3,4-methylenedioxymethamphetamine (MDMA or ‘ecstasy’) can have detrimental effects on the cognitive functions, but the…”
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Alzheimer's lymphocytes are resistant to ultraviolet B-induced apoptosis by Zana, Marianna, Juhász, Anna, Rimanóczy, Ágnes, Bjelik, Annamária, Baltás, Eszter, Ocsovszki, Imre, Boda, Krisztina, Penke, Botond, Dobozy, Attila, Kemény, Lajos, Janka, Zoltán, Kálmán, János

“…In the present pilot investigation, the susceptibility of T-lymphocytes from Alzheimer's disease (AD) subjects ( n = 22) and aged-matched, non-demented…”
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CYP46 T/C polymorphism is not associated with Alzheimer's dementia in a population from Hungary by Juhász, Anna, Rimanóczy, Agnes, Boda, Krisztina, Vincze, Gábor, Szlávik, Gyozo, Zana, Marianna, Bjelik, Annamária, Pákáski, Magdolna, Bódi, Nikoletta, Palotás, András, Janka, Zoltán, Kálmán, János

“…Multiple genetic and environmental factors regulate the susceptibility to Alzheimer's disease (AD). Recently, several independent studies have reported that a…”
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Impact of haloperidol and risperidone on gene expression profile in the rat cortex by Fehér, Liliána Z., Kálmán, János, Puskás, László G., Gyülvészi, Gábor, Kitajka, Klára, Penke, Botond, Palotás, Miklós, Samarova, Elena I., Molnár, József, Zvara, Ágnes, Matin, Keyvan, Bódi, Nikoletta, Hugyecz, Marietta, Pákáski, Magdolna, Bjelik, Annamária, Juhász, Anna, Bogáts, Gábor, Janka, Zoltán, Palotás, András

“…Despite the clinical efficacy of the most thoroughly studied conventional neuroleptic agent haloperidol, and the atypical antipsychotic risperidone is well…”
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AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease by Billes, Viktor, Kovács, Tibor, Hotzi, Bernadette, Manzéger, Anna, Tagscherer, Kinga, Komlós, Marcell, Tarnóci, Anna, Pádár, Zsolt, Erdős, Attila, Bjelik, Annamaria, Legradi, Adam, Gulya, Károly, Gulyás, Balázs, Vellai, Tibor

“…Autophagy, a lysosome-mediated self-degradation process of eukaryotic cells, serves as a main route for the elimination of cellular damage [1-3]. Such damages…”
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Impact of haloperidol and risperidone on gene expression profile in the rat cortex by FEHER, Liliana Z, KALMAN, Janos, MATIN, Keyvan, BODI, Nikoletta, HUGYECZ, Marietta, PAKASKI, Magdolna, BJELIK, Annamaria, JUHASZ, Anna, BOGATS, Gabor, JANKA, Zoltan, PALOTAS, Andras, PUSKAS, Laszlo G, GYÜLVESZI, Gabor, KITAJKA, Klara, PENKE, Botond, PALOTAS, Miklos, SAMAROVA, Elena I, MOLNAR, Jozsef, ZVARA, Agnes

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Interaction of Amyloid Precursor Protein and Lipid Metabolism with Relevance to Alzheimer's Disease by Bjelik, Annamária

“…Pathomechanism of Alzheimer's diseaseAlzheimer's disease (AD), the most common form of dementia in the western - world, currently affects 18 million people…”
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