Search Results - "BJARTMAR, C"

Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease by Bjartmar, C, Wujek, J.R, Trapp, B.D

“…Axonal degeneration has been identified as the major determinant of irreversible neurological disability in patients with multiple sclerosis (MS). Axonal…”
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Axonal loss in normal-appearing white matter in a patient with acute MS by BJARTMAR, C, KINKEL, R. P, KIDD, G, RUDICK, R. A, TRAPP, B. D

“…Brain imaging studies detect abnormalities in normal-appearing white matter in patients with MS. To investigate the histopathologic basis for these changes in…”
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Axon Loss in the Spinal Cord Determines Permanent Neurological Disability in an Animal Model of Multiple Sclerosis by WUJEK, JEROME R, BJARTMAR, CARL, RICHER, EDWARD, RANSOHOFF, RICHARD M, YU, MIN, TUOHY, VINCENT K, TRAPP, BRUCE D

“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Most patients undergo an initial relapsing-remitting…”
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T.P.24 by Thurberg, B.L, van der Ploeg, A, Kissel, J.T, Schoser, B, Pestronk, A, Barohn, R.J, Goker-Alpan, O, Mozaffar, T, Pena, L.D.M, Simmons, Z, Straub, V, Young, P, Bjartmar, C

“…Clearance of lysosomal glycogen has been shown after treatment with ERT (alglucosidase alfa) in LOPD patients. However, there is little data assessing glycogen…”
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Myelinated nerve fibres in the CNS by Hildebrand, C, Remahl, S, Persson, H, Bjartmar, C

“…(1) Lamellated glial sheaths surrounding axons, and electrogenetically active axolemmal foci have evolved independently in widely different phyla. In addition…”
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Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences by Bjartmar, C, Trapp, B D

“…Renewed interest in axonal injury in multiple sclerosis has significantly shifted the focus of research into this disease toward neurodegeneration. During the…”
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Cellular and extracellular components at nodes of Ranvier in rat white matter by Bjartmar, C, Karlsson, B, Hildebrand, C

“…Rat CNS nodes of Ranvier were investigated by electron microscopy and immunohistochemistry. Nodes along thin callosal axons possess tiny node gaps containing…”
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Neurological disability correlates with spinal cord axonal loss and reduced N-acetyl aspartate in chronic multiple sclerosis patients by Bjartmar, Carl, Kidd, Grahame, Mörk, Sverre, Rudick, Richard, Trapp, Bruce D.

“…Axonal degeneration has been proposed as a cause of irreversible neurological disability in multiple sclerosis (MS) patients. The purpose of this study was to…”
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Sheath lengths of large motor axons in the ventral root L5 of neonatal and adult rats by Hildebrand, C., Loeliger, S., Bjartmar, C., Karlsson, M.

“…This study examines the developmental sheath elongation in the rat ventral root L5. Electron microscopic analysis of serial transverse sections through roots…”
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N-acetylaspartate is an axon-specific marker of mature white matter in vivo: A biochemical and immunohistochemical study on the rat optic nerve by Bjartmar, Carl, Battistuta, Jan, Terada, Nobuo, Dupree, Erica, Trapp, Bruce D.

“…Axonal pathology is a major cause of neurological disability in multiple sclerosis. Axonal transection begins at disease onset but remains clinically silent…”
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Axonal degeneration and progressive neurologic disability in multiple sclerosis by Bjartmar, Carl, Trapp, Bruce D

“…Accumulating data support axonal degeneration as the major determinant of irreversible neurological disability in patients with multiple sclerosis (MS). The…”
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T.P.24: Alglucosidase alfa reduces lysosomal glycogen in skeletal muscle biopsies of patients with late-onset Pompe disease (LOPD) by Thurberg, B.L., van der Ploeg, A., Kissel, J.T., Schoser, B., Pestronk, A., Barohn, R.J., Goker-Alpan, O., Mozaffar, T., Pena, L.D.M., Simmons, Z., Straub, V., Young, P., Bjartmar, C.

“…Clearance of lysosomal glycogen has been shown after treatment with ERT (alglucosidase alfa) in LOPD patients. However, there is little data assessing glycogen…”
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A real-time insight into disease progression and the role of axonal injury in multiple sclerosis by Bjartmar, C, Kidd, G, Ransohoff, R M

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Morphological heterogeneity of cultured spinal and cerebral rat oligodendrocytes by Bjartmar, Carl

“…Oligodendrocytes in different central nervous system regions have dissimilar morphologies. In order to find out if immature oligodendrocytes develop different…”
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Morphological heterogeneity of rat oligodendrocytes: electron microscopic studies on serial sections by Bjartmar, C, Hildebrand, C, Loinder, K

“…The microanatomy of ensheathing and early myelinating rat oligodendrocytes was analyzed through electron microscopic examination of serial sections. The study…”
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Myelination of prospective large fibres in chicken ventral funiculus by Anderson, E S, Bjartmar, C, Hildebrand, C

“…In mammals, the oligodendrocyte population includes morphological and molecular varieties. We reported previously that an antiserum against the T4-O molecule…”
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Oligodendroglial sheath lengths in developing rat ventral funiculus and corpus callosum by Bjartmar, Carl

“…The lengths of uncompacted and partly compacted oligodendroglial sheaths in the developing rat spinal cord (SC) ventral funiculus (ages F19 and F21) and corpus…”
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Postmortem degradation of N-acetyl aspartate and N-acetyl aspartylglutamate: An HPLC analysis of different rat CNS regions by BATTISTUTA, Jan, BJARTMAR, Carl, TRAPP, Bruce D

“…N-acetyl aspartate (NAA), a putative marker of neuronal injury, can be measured non-invasively in patients by magnetic resonance spectroscopy (MRS)…”
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Oligodendrocytes have a key role in the development of CNS function and in myelin related diseases by Anderson, E S, Bjartmar, C

“…Oligodendrocytes provide CNS axons with myelin sheaths through processes of various lengths. The lipid-rich myelin insulates axons electrically, which…”
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Molecular heterogeneity of oligodendrocytes in chicken white matter by Anderson, Emma S., Bjartmar, Carl, Westermark, Gunilla, Hildebrand, Claes

“…The classical studies by Del Rio Hortega (Mem. Real. Soc. Espan. Hist. Nat. 14:40–122, 1928) suggest that the oligodendrocyte population includes four…”
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