Search Results - "BJØRN, S. E"

GlycoPEGylated rFVIIa (N7‐GP) has a prolonged hemostatic effect in hemophilic mice compared with rFVIIa by HOLMBERG, H., ELM, T., KARPF, D., TRANHOLM, M., BJØRN, S. E., STENNICKE, H., EZBAN, M.

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Structural Insights into Retinal Guanylylcyclase–GCAP-2 Interaction Determined by Cross-Linking and Mass Spectrometry by Pettelkau, Jens, Schröder, Thomas, Ihling, Christian H, Olausson, Björn E. S, Kölbel, Knut, Lange, Christian, Sinz, Andrea

“…The retinal guanylylcyclases ROS-GC 1 and 2 are regulated via the intracellular site by guanylylcyclase-activating proteins (GCAPs). The mechanisms of how…”
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The C-terminus of tissue factor pathway inhibitor (TFPI) is essential to its anticoagulant activity by Nordfang, Ole, Bjoern, Soeren E, Valentin, Sanne, Nielsen, Lars S, Wildgoose, Peter, Beck, Thomas C, Hedner, Ulla

“…Tissue factor pathway inhibitor (TFPI) from different cell lines shows up to 15-fold differences in the ratio of anticoagulant to chromogenic activity. The…”
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Antifungal activity of chitin-binding PR-4 type proteins from barley grain and stressed leaf by Hejgaard, Jørn, Jacobsen, Susanne, Bjørn, Søren E., Kragh, Karsten M.

“…Antifungal activity in vitro has been associated with barley leaf and grain proteins which are homologous with pathogenesis related proteins of type 4 (PR-4)…”
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Serpins from wheat grain by Rosenkrands, Ida, Hejgaard, Jørn, Rasmussen, Søren K., Bjørn, Søren E.

“…Wheat serpin genes have been identified by Southern blot hybridization with three distinct barley protein Z probes. Immunoblot analysis with a monoclonal…”
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Purification and characterization of the trefoil peptide human spasmolytic polypeptide (hSP) produced in yeast by Thim, Lars, Norris, Kjeld, Norris, Fanny, Nielsen, Per F., Bjørn, Søren E., Christensen, Mogens, Petersen, Jørgen

“…Recombinant human spasmolytic polypeptide (r-hSP) has been produced in relatively large amounts in Saccharomyces cerevisiae. The two intronless trefoil domains…”
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Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs by Moestrup, S K, Cui, S, Vorum, H, Bregengård, C, Bjørn, S E, Norris, K, Gliemann, J, Christensen, E I

“…Glycoprotein 330 (gp330) is an endocytic receptor expressed in the renal proximal tubules and some other absorptive epithelia, e.g., in the inner ear. The…”
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Characterization of human tissue factor pathway inhibitor variants expressed in Saccharomyces cerevisiae by PETERSEN, J. G. L, MEYN, G, RASMUSSEN, J. S, PETERSEN, J, BJØRN, S. E, JONASSEN, I, CHRISTIANSEN, L, NORDFANG, O

“…Human tissue factor pathway inhibitor (TFPI) and three derivatives with deletions of: 1) the complete COOH-terminal third of the polypeptide including the…”
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Expression, purification and characterization of a Kunitz-type protease inhibitor domain from human amyloid precursor protein homolog by Petersen, Lars C., Bjørn, Søren E., Norris, Fanny, Norris, Kjeld, Sprecher, Cindy, Foster, Donald C.

“…The Kunitz-type protease inhibitor domain from a recently identified homolog of the Alzheimer amyloid precursor protein (APPH KPI) was expressed in yeast,…”
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Recombinant activated factor VII (rFVIIa): characterization, manufacturing, and clinical development by Jurlander, B, Thim, L, Klausen, N K, Persson, E, Kjalke, M, Rexen, P, Jørgensen, T B, Østergaard, P B, Erhardtsen, E, Bjørn, S E

“…Recombinant activated coagulation factor VII (rFVIIa) (NovoSeven) was developed for treatment of bleeding in hemophilia patients with inhibitors (antibodies)…”
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Localization to chromosomes of structural genes for the major protease inhibitors of barley grains by Hejgaard, J, Bjorn, S.E, Nielsen, G

“…Wheat-barley chromosome addition lines were compared by isoelectric focusing of protein extracts to identify chromosomes carrying loci for the major…”
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Primary structure and specificity of the major serine proteinase inhibitor of amaranth (Amaranthus caudatus L.) seeds by Hejgaard, J, Dam, J, Petersen, L C, Bjørn, S E

“…A novel member of the potato inhibitor I family of serine proteinase inactivating proteins has been isolated from seeds of grain amaranth (Amaranthus caudatus…”
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Structure and function of the N-linked glycans of HBP/CAP37/azurocidin: Crystal structure determination and biological characterization of nonglycosylated HBP by IVERSEN, L.F., KASTRUP, J.S., BJØRN, S.E., WIBERG, F.C., LARSEN, I.K., FLODGAARD, H.J., RASMUSSEN, P.B.

“…The three N-glycosylation sites of human heparin binding protein (HBP) have been mutated to produce a nonglycosylated HBP (ng-HBP) mutant. ng-HBP has been…”
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Effect of leukocyte proteinases on tissue factor pathway inhibitor by Petersen, L C, Bjørn, S E, Nordfang, O

“…The effect of human neutrophil elastase and cathepsin G on recombinant tissue factor pathway inhibitor (TFPI) was investigated. A weak inhibition by TFPI of…”
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Binding and endocytosis of proteins mediated by epithelial gp330 by Moestrup, S K, Christensen, E I, Nielsen, S, Jørgensen, K E, Bjørn, S E, Røigaard, H, Gliemann, J

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Inhibitory Properties of Separate Recombinant Kunitz‐Type‐Protease‐Inhibitor Domains from Tissue‐Factor‐Pathway Inhibitor by Petersen, Lars C., Bjørn, Søren E., Olsen, Ole H., Nordfang, Ole, Norris, Fanny, Norris, Kjeld

“…Tissue‐factor‐pathway inhibitor (TFPT) is a multivalent inhibitor with three tandemly arranged Kunitz‐type‐protease‐inhibitor (KPI) domains. Previous studies…”
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Prolonged effect of GlycoPEGylated rFVIIa (40k-PEG-rFVIIa) in rabbits correlates to activity in plasma by Johansen, Peter B, Bjørn, Søren E, Agersø, Henrik, Thorup, Inger, Hermit, Mette B, Sørensen, Brit, Stennicke, Henning R, Ezban, Mirella, Tranholm, Mikael

“…The pharmacokinetics and pharmacodynamics of 40k-PEG-rFVIIa, a GlycoPEGylated derivative of recombinant wild-type FVIIa, were compared with rFVIIa in rabbits…”
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Aprotinin and aprotinin analogues expressed in yeast by Norris, K, Norris, F, Bjørn, S E, Diers, I, Peterson, L C

“…Synthetic genes encoding aprotinin and aprotinin analogues were constructed and fused in frame to the S. cerevisiae mating factor alpha 1 signal-leader (1-85)…”
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Structure of HBP, a multifunctional protein with a serine proteinase fold by Iversen, Lars Fogh, Kastrup, Jette Sandholm, Bjørn, Søren Erik, Rasmussen, Poul Baad, Wiberg, Finn Christoph, Flodgaard, Hans Jacob, Larsen, Ingrid Kjøller

“…The structure of human heparin binding protein reveals that the serine proteinase fold has been used as a scaffold for a multifunctional protein with…”
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Identification of aprotinin degradation products by the use of high-performance capillary electrophoresis, high-pressure liquid chromatography and mass spectrometry by Vinther, A, Bjørn, S E, Sørensen, H H, Søeberg, H

“…A preparation of bovine aprotinin, bovine pancreatic trypsin inhibitor, was subjected to high-performance capillary electrophoresis (HPCE) analysis and the…”
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