Search Results - "BJÖRNSSON, Einar"
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Hepatotoxicity by Drugs: The Most Common Implicated Agents
Published in International journal of molecular sciences (06-02-2016)“…Idiosyncratic drug-induced liver injury (DILI) is an underreported and underestimated adverse drug reaction. Information on the documented hepatotoxicity of…”
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Categorization of drugs implicated in causing liver injury: Critical assessment based on published case reports
Published in Hepatology (Baltimore, Md.) (01-02-2016)“…An important element in assessing causality in drug‐induced liver injury is whether the implicated agent is known to cause hepatotoxicity. We classified drugs…”
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Hepatotoxicity of statins and other lipid‐lowering agents
Published in Liver international (01-02-2017)“…Statins are generally well tolerated and adverse effects are relatively rare. Clinical trials are underpowered to detect uncommon adverse effects such as…”
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EASL Clinical Practice Guidelines: Drug-induced liver injury
Published in Journal of hepatology (01-06-2019)“…Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver disorders faced by hepatologists, because of the myriad of drugs…”
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Drug-Induced Liver Injury — Types and Phenotypes
Published in The New England journal of medicine (18-07-2019)“…The liver has a range of responses to drug-induced injury, with a number of phenotypes. In addition, idiosyncratic reactions may occur as a consequence of both…”
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Editorial: Plants against animals
Published in Alimentary pharmacology & therapeutics (01-10-2024)“…LINKED CONTENT This article is linked to Choi et al paper. To view this article, visit https://doi.org/10.1111/apt.18116…”
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Drug-induced liver injury due to antibiotics
Published in Scandinavian journal of gastroenterology (03-07-2017)“…Drug-induced liver injury (DILI) is an important differential diagnosis in patients with abnormal liver tests and normal hepatobiliary imaging. Of all known…”
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Drug-induced liver injury: an overview over the most critical compounds
Published in Archives of toxicology (01-03-2015)“…There has been a substantial interest in drug-induced liver injury (DILI) recently. National Institutes of Health has sponsored a multicenter study in the USA…”
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Long-term sequelae of drug-induced liver injury
Published in Journal of hepatology (01-02-2022)“…Drug-induced liver injury (DILI) has a very variable clinical and biochemical phenotype and differs widely in severity, from mild injury to life-threatening…”
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Epidemiology, Predisposing Factors, and Outcomes of Drug-Induced Liver Injury
Published in Clinics in liver disease (01-02-2020)“…Idiosyncratic drug-induced liver injury (DILI) is an underreported and underestimated adverse drug reaction. A recent population-based study found a crude…”
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Liver injury associated with the analgetic drug metamizole
Published in British journal of clinical pharmacology (01-07-2020)Get full text
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The Safe Use of Analgesics in Patients with Cirrhosis: A Narrative Review
Published in The American journal of medicine (01-02-2024)“…Pain is prevalent in patients with cirrhosis. Due to potential alterations in drug metabolism, risk for adverse effects, and complications from cirrhosis,…”
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Liver Injury Associated with the Selective Progesterone Modulator Ulipristal
Published in Drug safety (01-12-2020)“…In one population-based study in Iceland, DILI occurred in 1 of 2350 users of amoxicillin-clavulanate [14]. [...]the clinical trials with UPA were obviously…”
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Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2013)“…Background & Aims Little is known about the incidence of drug-induced liver injury (DILI) in the general population. We investigated the incidence and the…”
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Epidemiology and risk factors for idiosyncratic drug-induced liver injury
Published in Seminars in liver disease (01-05-2014)“…Idiosyncratic drug-induced liver injury (DILI) is, like other adverse effects of drugs, underreported and underestimated in most epidemiological studies based…”
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Drug-induced liver injury
Published in Nature reviews. Disease primers (22-08-2019)“…Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed…”
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Infliximab-induced liver injury: Clinical phenotypes, autoimmunity and the role of corticosteroid treatment
Published in Journal of hepatology (01-01-2022)“…Infliximab has been associated with drug-induced liver injury (DILI), particularly drug-induced autoimmune hepatitis (DIAIH). DIAIH is commonly treated with…”
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Clinical management of patients with drug‐induced liver injury (DILI)
Published in United European gastroenterology journal (01-09-2021)“…Drug‐induced liver injury (DILI) should be considered in all patients with recent elevation of liver tests without obvious etiology and normal hepatobiliary…”
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Liver fibrosis with methotrexate — an overestimated risk?
Published in Nature reviews. Gastroenterology & hepatology (01-06-2023)“…A prospective study suggests that the risk of liver fibrosis with methotrexate treatment has been overestimated. The findings suggest the need to reconsider…”
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Drug-Induced Liver Injury due to Biologics and Immune Check Point Inhibitors
Published in The Medical clinics of North America (01-05-2023)“…Biological agents have in the last two decades become very important therapeutic agents, particularly for the treatment of various autoimmune disorders. The…”
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