Search Results - "BIYAN DUAN"
-
1
Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events
Published in Signal transduction and targeted therapy (26-04-2022)“…The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants. Ongoing concerns of emergent variants include possible recombinants,…”
Get full text
Journal Article -
2
Altered Lipid Profile in COVID-19 Patients and Metabolic Reprogramming
Published in Frontiers in microbiology (12-05-2022)“…Coronavirus disease 2019 (COVID-19) is a global pandemic. Previous studies have reported dyslipidemia in patients with COVID-19. Herein, we conducted a…”
Get full text
Journal Article -
3
Th17-stimulating Protein Vaccines Confer Protection against Pseudomonas aeruginosa Pneumonia
Published in American journal of respiratory and critical care medicine (01-09-2012)“…New vaccine approaches are needed for Pseudomonas aeruginosa, which continues to be a major cause of serious pulmonary infections. Although Th17 cells can…”
Get full text
Journal Article -
4
SDF-1/CXCR4 axis modulates bone marrow mesenchymal stem cell apoptosis, migration and cytokine secretion
Published in Protein & cell (01-10-2011)“…Bone marrow mesenchymal stem cells (MSCs) are considered as a promising cell source to treat the acute myocardial infarction. However, over 90% of the stem…”
Get full text
Journal Article -
5
Vascular endothelial growth inhibitor (VEGI; TNFSF15) inhibits bone marrow-derived endothelial progenitor cell incorporation into Lewis lung carcinoma tumors
Published in Angiogenesis (London) (01-03-2011)“…Bone marrow (BM)-derived endothelial progenitor cells (EPC) have a critical role in tumor neovascularization. Vascular endothelial growth inhibitor (VEGI) is a…”
Get full text
Journal Article -
6
Lupus resistance is associated with marginal zone abnormalities in an NZM murine model
Published in Laboratory investigation (01-01-2007)“…The NZM2410 and NZM TAN (TAN) are two of 27 inbred strains derived from an intercross between the NZW and NZB strains. NZM2410 mice develop a highly penetrant…”
Get full text
Journal Article -
7
STAT4 deficiency reduces autoantibody production and glomerulonephritis in a mouse model of lupus
Published in Clinical Immunology (01-08-2006)“…To determine the respective role of the IL-12 and IL-4 pathways in the pathogenesis of systemic lupus erythematosus, we bred the Stat4 and Stat6 null alleles…”
Get full text
Journal Article -
8
A Genetic Lesion That Arrests Plasma Cell Homing to the Bone Marrow
Published in Proceedings of the National Academy of Sciences - PNAS (28-10-2003)“…The coordinated regulation of chemokine responsiveness plays a critical role in the development of humoral immunity. After antigen challenge and B cell…”
Get full text
Journal Article -
9
Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia
Published in Infection and immunity (01-10-2015)“…Th17 immunity in the gastrointestinal tract is regulated by the intestinal microbiota composition, particularly the presence of segmented filamentous bacteria…”
Get full text
Journal Article -
10
Isolation of novel simian adenoviruses from macaques for development of a vector for human gene therapy and vaccines
Published in Journal of virology (15-09-2023)“…Both human and non-human simian adenoviruses (HAdVs and SAdVs, respectively) have been used as gene therapy and vaccine vectors. The high prevalence of HAdVs…”
Get full text
Journal Article -
11
PLGA-encapsulation of the Pseudomonas aeruginosa PopB vaccine antigen improves Th17 responses and confers protection against experimental acute pneumonia
Published in Vaccine (12-11-2018)“…•Pseudomonas aeruginosa PopB was encapsulated into PLGA nanoparticles.•Vaccination with PopB-PLGA protected against lethal P. aeruginosa challenge.•PopB-PLGA…”
Get full text
Journal Article -
12
Direct B cell stimulation by dendritic cells in a mouse model of lupus
Published in Arthritis and rheumatism (01-06-2008)“…Objective Dendritic cells (DCs) play a major role in regulating lymphocytes, including B cells, and defective DC functions have been implicated in lupus. The…”
Get full text
Journal Article -
13
Distinct roles of adenylyl cyclase VII in regulating the immune responses in mice
Published in The Journal of immunology (1950) (01-07-2010)“…The second messenger cAMP plays a critical role in regulating immune responses. Although well known for its immunosuppressive effect, cAMP is also required for…”
Get full text
Journal Article -
14
Construction and validation of a mouse model for studying severe human adenovirus infections
Published in Virologica Sinica (06-11-2024)“…Human adenoviruses (HAdVs) are highly contagious pathogens with various genotypes implicated in acute respiratory disease (ARD) and linked to mortality,…”
Get full text
Journal Article -
15
Abstract 4314: A mouse model of cerebral cavernous malformations
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Cerebral cavernous malformations (CCM) are prevalent cerebral vascular lesions involving aberrant angiogenesis that can lead to hemorrhage, epilepsy,…”
Get full text
Journal Article -
16
Intrafollicular location of marginal zone CD1d B cells is associated with autoimmune pathology in a mouse model of lupus
Published in Laboratory investigation (01-09-2008)“…Marginal zone (MZ) B cells contain a large number of autoreactive clones and the expansion of this compartment has been associated with autoimmunity. MZ B…”
Get full text
Journal Article -
17
Genetics of autoreactive B cells
Published in Frontiers in bioscience (01-01-2007)“…It is now well-accepted that autoimmune diseases develop as a result of interactions between a complex genetic basis and environmental triggers. Autoreactive B…”
Get full text
Journal Article -
18
Genetic Dissection of the Murine Lupus Susceptibility Locus Sle2: Contributions to Increased Peritoneal B-1a Cells and Lupus Nephritis Map to Different Loci
Published in The Journal of immunology (1950) (15-07-2005)“…Lupus pathogenesis in the NZM2410 mouse model results from the expression of multiple interacting susceptibility loci. Sle2 on chromosome 4 was significantly…”
Get full text
Journal Article -
19
Intrafollicular location of marginal zone/CD1d super(hi) B cells is associated with autoimmune pathology in a mouse model of lupus
Published in Laboratory investigation (01-09-2008)“…Marginal zone (MZ) B cells contain a large number of autoreactive clones and the expansion of this compartment has been associated with autoimmunity. MZ B…”
Get full text
Journal Article -
20
Intrafollicular location of marginal zone/CD1dhi B cells is associated with autoimmune pathology in a mouse model of lupus
Published in Laboratory investigation (01-09-2008)“…Marginal zone (MZ) B cells contain a large number of autoreactive clones and the expansion of this compartment has been associated with autoimmunity. MZ B…”
Get full text
Journal Article