Search Results - "BITON, V"

Tolerability and safety of perampanel: two randomized dose-escalation studies by Krauss, G. L., Bar, M., Biton, V., Klapper, J. A., Rektor, I., Vaiciene-Magistris, N., Squillacote, D., Kumar, D.

“…Krauss GL, Bar M, Biton V, Klapper JA, Rektor I, Vaiciene‐Magistris N, Squillacote D, Kumar D. Tolerability and safety of perampanel: two randomized…”
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Perampanel Study 207: long-term open-label evaluation in patients with epilepsy by Rektor, I., Krauss, G. L., Bar, M., Biton, V., Klapper, J. A., Vaiciene-Magistris, N., Kuba, R., Squillacote, D., Gee, M., Kumar, D.

“…Objectives Evaluate interim long‐term tolerability, safety and efficacy of adjunctive perampanel, a novel α‐amino‐3‐hydroxy‐5‐methyl‐5‐isoxazolepropionic acid…”
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Levetiracetam for partial seizures : Results of a double-blind, randomized clinical trial by CEREGHINO, J. J, BITON, V, ABOU-KHALIL, B, DREIFUSS, F, GAUER, L. J, LEPPIK, I

“…To evaluate the efficacy and safety of 500 mg bid and 1500 mg bid levetiracetam as adjunctive therapy for refractory partial seizures in a double-blind,…”
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Cognitive effects of lamotrigine compared with topiramate in patients with epilepsy by BLUM, D, MEADOR, K, BITON, V, FAKHOURY, T, SHNEKER, B, CHUNG, S, MILLS, K, HAMMER, A, ISOJÄRVI, J

“…To compare the cognitive effects of lamotrigine vs topiramate as adjunctive therapy in adults with epilepsy. A multicenter, double-blind, randomized,…”
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A randomized, placebo-controlled study of topiramate in primary generalized tonic-clonic seizures by BITON, V, MONTOURIS, G. D, RITTER, F, RIVIELLO, J. J, REIFE, R, LIM, P, PLEDGER, G

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Double-blind, placebo-controlled study of lamotrigine in primary generalized tonic-clonic seizures by BITON, V, SACKELLARES, J. C, VUONG, A, HAMMER, A. E, BARRETT, P. S, MESSENHEIMER, J. A

“…To evaluate the efficacy and tolerability of adjunctive lamotrigine in primary generalized tonic-clonic (PGTC) seizures in a randomized, double-blind,…”
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Weight change associated with valproate and lamotrigine monotherapy in patients with epilepsy by BITON, V, MIRZA, W, MONTOURIS, G, VUONG, A, HAMMER, A. E, BARRETT, P. S

“…To compare the incidence and magnitude of change in body weight associated with lamotrigine or divalproex sodium monotherapy in patients with epilepsy. A…”
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Topiramate titration and tolerability by Biton, V, Edwards, KR, Montouris, GD, Sackellares, JC, Harden, CL, Kamin, M

“…OBJECTIVE: To evaluate the tolerability and efficacy of two titration rates for topiramate initiated as adjunctive therapy in adults with partial-onset…”
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Preliminary Open‐Label Experience with Topiramate in Primary Generalized Seizures by Biton, Victor

“…Preliminary data concerning the effectiveness of topiramate (TPM) in the management of resistant primary generalized seizures were obtained from the open‐label…”
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Clinical pharmacology and mechanism of action of zonisamide by Biton, Victor

“…Antiepileptic drugs (AEDs) suppress seizures by selectively modifying the excitability of neurons and blocking seizure firing with minimal disturbance of…”
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Effect of antiepileptic drugs on bodyweight: Overview and clinical implications for the treatment of epilepsy by BITON, Victor

“…The potential of specific antiepileptic drugs (AEDs) to cause clinically significant changes in bodyweight is a key consideration in the management of…”
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Long‐term safety and efficacy of lacosamide and controlled‐release carbamazepine monotherapy in patients with newly diagnosed epilepsy by Ben‐Menachem, Elinor, Grebe, Hans Peter, Terada, Kiyohito, Jensen, Lori, Li, Ting, De Backer, Marc, Steiniger‐Brach, Björn, Gasalla, Teresa, Brock, Melissa, Biton, Victor

“…Objective A large‐scale, double‐blind trial (SP0993; NCT01243177) demonstrated that lacosamide was noninferior to controlled‐release carbamazepine…”
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Lacosamide for the treatment of diabetic neuropathic pain by Biton, Victor

“…Lacosamide is a novel chemical entity with anticonvulsant and analgesic properties that is being developed to treat epilepsy and neuropathic pain conditions…”
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Pharmacokinetics, toxicology and safety of lamotrigine in epilepsy by Biton, Victor

“…Optimisation of pharmacotherapy for epilepsy requires consideration of the impact of drug metabolism and toxicology on the therapeutic profiles and clinical…”
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Lacosamide in Painful Diabetic Peripheral Neuropathy: A Phase 2 Double-blind Placebo-controlled Study by Rauck, Richard L, Shaibani, Aziz, Biton, Victor, Simpson, Jeff, Koch, Brigitte

“…BACKGROUNDPeripheral diabetic neuropathy affects between 20% and 45% of patients with diabetes. OBJECTIVETo ascertain the effect of lacosamide on pain…”
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Psychiatric and cognitive adverse events: A pooled analysis of three phase III trials of adjunctive eslicarbazepine acetate for partial-onset seizures by Andermann, Eva, Biton, Victor, Benbadis, Selim R., Shneker, Bassel, Shah, Aashit K., Carreño, Mar, Trinka, Eugen, Ben-Menachem, Elinor, Biraben, Arnaud, Rocha, Francisco, Gama, Helena, Cheng, Hailong, Blum, David

“…To evaluate the nature and incidence of psychiatric and cognitive adverse events (AEs) reported with eslicarbazepine acetate (ESL) used as adjunctive treatment…”
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Biomarker pattern of ARIA-E participants in phase 3 randomized clinical trials with bapineuzumab by Liu, Enchi, Wang, Dai, Sperling, Reisa, Salloway, Stephen, Fox, Nick C, Blennow, Kaj, Scheltens, Philip, Schmidt, Mark E, Streffer, Johannes, Novak, Gerald, Einstein, Steve, Booth, Kevin, Ketter, Nzeera, Brashear, H Robert

“…OBJECTIVETo evaluate whether amyloid-related imaging abnormalities with edema/effusion (ARIA-E) observed in bapineuzumab clinical trials was associated with…”
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Long-term oral lacosamide in painful diabetic neuropathy: A two-year open-label extension trial by Shaibani, Aziz, Biton, Victor, Rauck, Richard, Koch, Brigitte, Simpson, Jeffrey

“…Abstract Objectives This open-label follow-on trial aimed to investigate long-term safety and efficacy of lacosamide in patients with painful diabetic…”
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Alemtuzumab vs. Interferon Beta-1a in Early Multiple Sclerosis by Coles, Alasdair J, Compston, D Alastair S, Selmaj, Krzysztof W, Lake, Stephen L, Moran, Susan, Margolin, David H, Norris, Kim, Tandon, P K

“…In this randomized, phase 2 trial involving previously untreated patients with early, relapsing–remitting multiple sclerosis, alemtuzumab, a monoclonal…”
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Gabapentin Extended Release for the Treatment of Painful Diabetic Peripheral Neuropathy by Sandercock, David, Cramer, Marilou, Wu, Jacqueline, Chiang, Yu-Kun, Biton, Victor, Heritier, Michelle

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