Search Results - "BISIO, Margarita"

Listen to what the animals say: a systematic review and meta-analysis of sterol 14-demethylase inhibitor efficacy for in vivo models of Trypanosoma cruzi infection by Bisio, Margarita María Catalina, Jurado Medina, Laura Smeldy, García-Bournissen, Facundo, Gulin, Julián Ernesto Nicolás

“…Sterol 14-demethylase (CYP51) inhibitors, encompassing new chemical entities and repurposed drugs, have emerged as promising candidates for Chagas disease…”
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Secretome analysis of Trypanosoma cruzi by proteomics studies by Brossas, Jean-Yves, Gulin, Julián Ernesto Nicolás, Bisio, Margarita Maria Catalina, Chapelle, Manuel, Marinach-Patrice, Carine, Bordessoules, Mallaury, Palazon Ruiz, George, Vion, Jeremy, Paris, Luc, Altcheh, Jaime, Mazier, Dominique

“…Chagas disease is a debilitating often fatal disease resulting from infection by the protozoan parasite Trypanosoma cruzi. Chagas disease is endemic in 21…”
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Prevention of congenital Chagas through treatment of girls and women of childbearing age by Moscatelli, Guillermo, Moroni, Samanta, García-Bournissen, Facundo, Ballering, Griselda, Bisio, Margarita, Freilij, Héctor, Altcheh, Jaime

“…It is currently unknown whether treatment of Chagas disease decreases the risk of congenital transmission from previously treated mothers to their infants. In…”
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Comparative evaluation of four rapid diagnostic tests that detect human Trypanosoma cruzi-specific antibodies to support diagnosis of Chagas Disease in urban population of Argentina by Rivero, Rocío, Santini, M Soledad, Lopez-Albizu, Constanza, Rodriguez, Marcelo, Calbosa, Adriana, Oliveto, Daniela, Esteva, Mónica, Bisio, Margarita, Bohorquez, Laura C

“…Chagas disease (CD), caused by the parasite Trypanosoma cruzi, is the most important endemic anthropozoonosis in Argentina. Since 2010, the World Health…”
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Population pharmacokinetic study of benznidazole in pediatric Chagas disease suggests efficacy despite lower plasma concentrations than in adults by Altcheh, Jaime, Moscatelli, Guillermo, Mastrantonio, Guido, Moroni, Samanta, Giglio, Norberto, Marson, Maria Elena, Ballering, Griselda, Bisio, Margarita, Koren, Gideon, García-Bournissen, Facundo

“…Chagas disease, caused by the parasite Trypanosoma cruzi, can lead to long term cardiac morbidity. Treatment of children with benznidazole is effective, but no…”
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Accurate real-time PCR strategy for monitoring bloodstream parasitic loads in chagas disease patients by Duffy, Tomas, Bisio, Margarita, Altcheh, Jaime, Burgos, Juan Miguel, Diez, Mirta, Levin, Mariano Jorge, Favaloro, Roberto Rene, Freilij, Hector, Schijman, Alejandro Gabriel

“…This report describes a real-time PCR (Q-PCR) strategy to quantify Trypanosoma cruzi (T. cruzi) DNA in peripheral blood samples from Chagas disease patients…”
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Longitudinal follow up of serological response in children treated for Chagas disease by Moscatelli, Guillermo, Moroni, Samanta, García Bournissen, Facundo, González, Nicolás, Ballering, Griselda, Schijman, Alejandro, Corral, Ricardo, Bisio, Margarita, Freilij, Héctor, Altcheh, Jaime

“…Evaluation of therapeutic response in chronic Chagas disease is a major challenge, due to prolonged persistence of Trypanosoma cruzi-specific antibodies, lack…”
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Miltefosine and Benznidazole Combination Improve Anti-Trypanosoma cruzi In Vitro and In Vivo Efficacy by Gulin, Julián Ernesto Nicolás, Bisio, Margarita María Catalina, Rocco, Daniela, Altcheh, Jaime, Solana, María Elisa, García-Bournissen, Facundo

“…Drug repurposing and combination therapy have been proposed as cost-effective strategies to improve Chagas disease treatment. Miltefosine (MLT), a synthetic…”
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Population pharmacokinetics of benznidazole in neonates, infants and children using a new pediatric formulation by Altcheh, Jaime, Moscatelli, Guillermo, Caruso, Martin, Moroni, Samanta, Bisio, Margarita, Miranda, Maria Rosa, Monla, Celia, Vaina, Maria, Valdez, Maria, Moran, Lucrecia, Ramirez, Teresa, Patiño, Oscar Ledesma, Riarte, Adelina, Gonzalez, Nicolas, Fernandes, Jayme, Alves, Fabiana, Ribeiro, Isabela, Garcia-Bournissen, Facundo

“…There is a major need for information on pharmacokinetics (PK) of benznidazole (BNZ) in children with Chagas disease (CD). We conducted a multicentre…”
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Diagnostic Accuracy of Two Molecular Tools for Diagnosis of Congenital Chagas Disease by Bisio, Margarita María Catalina, Rivero, Rocío, Gonzalez, Nicolás, Ballering, Griselda, D’Amico, Indira, Kessler, Camila, Moroni, Samanta, Moscatelli, Guillermo, Ruiz, Andrés Mariano, Altcheh, Jaime

“…Background and Objective The real prevalence of congenital Chagas disease is undefined because of difficulties in the detection of Trypanosoma cruzi by…”
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Negligible exposure to nifurtimox through breast milk during maternal treatment for Chagas Disease by Moroni, Samanta, Marson, Maria Elena, Moscatelli, Guillermo, Mastrantonio, Guido, Bisio, Margarita, Gonzalez, Nicolas, Ballering, Griselda, Altcheh, Jaime, García-Bournissen, Facundo

“…Treatment with nifurtimox (NF) for Chagas disease is discouraged during breast-feeding because no information on NF transfer into breast milk is available. NF…”
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Multiplex Real-Time PCR Assay Using TaqMan Probes for the Identification of Trypanosoma cruzi DTUs in Biological and Clinical Samples by Cura, Carolina I, Duffy, Tomas, Lucero, Raúl H, Bisio, Margarita, Péneau, Julie, Jimenez-Coello, Matilde, Calabuig, Eva, Gimenez, María J, Valencia Ayala, Edward, Kjos, Sonia A, Santalla, José, Mahaney, Susan M, Cayo, Nelly M, Nagel, Claudia, Barcán, Laura, Málaga Machaca, Edith S, Acosta Viana, Karla Y, Brutus, Laurent, Ocampo, Susana B, Aznar, Christine, Cuba Cuba, Cesar A, Gürtler, Ricardo E, Ramsey, Janine M, Ribeiro, Isabela, VandeBerg, John L, Yadon, Zaida E, Osuna, Antonio, Schijman, Alejandro G

“…Trypanosoma cruzi has been classified into six Discrete Typing Units (DTUs), designated as TcI-TcVI. In order to effectively use this standardized…”
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Benznidazole treatment of chagasic encephalitis in pregnant woman with AIDS by Bisio, Margarita, Altcheh, Jaime, Lattner, Jorge, Moscatelli, Guillermo, Fink, Valeria, Burgos, Juan M, Bournissen, Facundo García, Schijman, Alejandro G, Freilij, Héctor

“…We report a case of chagasic meningoencephalitis reactivation in a pregnant woman co-infected with Trypanosoma cruzi and HIV that was successfully managed with…”
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Evaluation of Nifurtimox Treatment of Chronic Chagas Disease by Means of Several Parasitological Methods by MUNOZ, Catalina, ZULANTAY, Inés, APT, Werner, ORTIZ, Sylvia, SCHIJMAN, Alejandro G, BISIO, Margarita, FERRADA, Valentina, HERRERA, Cinthya, MARTINEZ, Gabriela, SOLARI, Aldo

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Refining drug administration in a murine model of acute infection with Trypanosoma cruzi by Gulin, Julián Ernesto Nicolás, Bisio, Margarita, García-Bournissen, Facundo

“…In animal research, "refinement" refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain…”
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Evaluation of the Chagas Western Blot IgG Assay for the Diagnosis of Chagas Disease by Brossas, Jean-Yves, Griselda, Ballering, Bisio, Margarita, Guihenneuc, Jeremy, Gulin, Julián Ernesto Nicolás, Jauréguiberry, Stéphane, Lescure, François-Xavier, Fekkar, Arnaud, Mazier, Dominique, Altcheh, Jaime, Paris, Luc

“…Chagas disease is a debilitating and often fatal pathology resulting from infection by the protozoan parasite Trypanosoma cruzi. In its recommendations, the…”
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Serological based monitoring of a cohort of patients with chronic Chagas disease treated with benznidazole in a highly endemic area of northern Argentina by Niborski, Leticia L, Grippo, Vanina, Lafón, Sonia O, Levitus, Gabriela, García-Bournissen, Facundo, Ramirez, Juan C, Burgos, Juan M, Bisio, Margarita, Juiz, Natalia A, Ayala, Vilma, Coppede, María, Herrera, Verónica, López, Crescencia, Contreras, Ana, Gómez, Karina A, Elean, Juan C, Mujica, Hugo D, Schijman, Alejandro G, Levin, Mariano J, Longhi, Silvia A

“…This study aimed to evaluate well-documented diagnostic antigens, named B13, 1F8 and JL7 recombinant proteins, as potential markers of seroconversion in…”
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Clinical use of molecular methods for Trypanosoma cruzi infection in endemic and non-endemic countries: Benefits, limitations and challenges by Pinazo, Maria-Jesus, Forsyth, Colin J., Lopez-Albizu, Constanza, Bisio, Margarita María Catalina, González-Martínez, Adriana, Bohorquez, Laura, Pinto, Jimy, Molina, Israel, Marchiol, Andrea, Herazo, Rafael, Galván, Irene Losada, Marques, Tayná, Barreira, Fabiana, Villar, Juan Carlos, Sguassero, Yanina, Santini, Maria Soledad, Altcheh, Jaime, Alarcón de Noya, Belkisyolé, Sosa-Estani, Sergio

“…Trypanosoma cruzi infection is diagnosed by parasitological, molecular, and serological tests. Molecular methods based on DNA amplification provide a more…”
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Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial by Torrico, Faustino, Gascon, Joaquim, Ortiz, Lourdes, Alonso-Vega, Cristina, Pinazo, María-Jesús, Schijman, Alejandro, Almeida, Igor C, Alves, Fabiana, Strub-Wourgaft, Nathalie, Ribeiro, Isabela, Santina, Glaucia, Blum, Bethania, Correia, Erika, Garcia-Bournisen, Facundo, Vaillant, Michel, Morales, Jimena Ramos, Pinto Rocha, Jimy Jose, Rojas Delgadillo, Gimena, Magne Anzoleaga, Helmut Ramon, Mendoza, Nilce, Quechover, Roxana Challapa, Caballero, Maria Yurly Escobar, Lozano Beltran, Daniel Franz, Zalabar, Albert Mendoza, Rojas Panozo, Lizeth, Palacios Lopez, Alejandro, Torrico Terceros, Dunia, Fernandez Galvez, Violeta Alejandra, Cardozo, Letty, Cuellar, Gabriela, Vasco Arenas, Rudy Nelson, Gonzales, Isabel, Hoyos Delfin, Carlos Florencio, Garcia, Lineth, Parrado, Rudy, de la Barra, Anabelle, Montano, Nair, Villarroel, Sandro, Duffy, Tomas, Bisio, Margarita, Ramirez, Juan Carlos, Duncanson, Fred, Everson, Michael, Daniels, Antonia, Asada, Makoto, Cox, Eugene, Wesche, David, Diderichsen, Paul Matthias, Marques, Alexandre F, Izquierdo, Luis, Sender, Silvia Sanz, Reverter, Joan Carlos, Morales, Manuel, Jimenez, Wladimiro

“…Chagas disease is a major neglected vector-borne disease. In this study, we investigated the safety and efficacy of three oral E1224 (a water-soluble…”
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Analytical Validation of Quantitative Real-Time PCR Methods for Quantification of Trypanosoma cruzi DNA in Blood Samples from Chagas Disease Patients by Ramírez, Juan Carlos, Cura, Carolina Inés, da Cruz Moreira, Otacilio, Lages-Silva, Eliane, Juiz, Natalia, Velázquez, Elsa, Ramírez, Juan David, Alberti, Anahí, Pavia, Paula, Flores-Chávez, María Delmans, Muñoz-Calderón, Arturo, Pérez-Morales, Deyanira, Santalla, José, Marcos da Matta Guedes, Paulo, Peneau, Julie, Marcet, Paula, Padilla, Carlos, Cruz-Robles, David, Valencia, Edward, Crisante, Gladys Elena, Greif, Gonzalo, Zulantay, Inés, Costales, Jaime Alfredo, Alvarez-Martínez, Miriam, Martínez, Norma Edith, Villarroel, Rodrigo, Villarroel, Sandro, Sánchez, Zunilda, Bisio, Margarita, Parrado, Rudy, Maria da Cunha Galvão, Lúcia, Jácome da Câmara, Antonia Cláudia, Espinoza, Bertha, Alarcón de Noya, Belkisyole, Puerta, Concepción, Riarte, Adelina, Diosque, Patricio, Sosa-Estani, Sergio, Guhl, Felipe, Ribeiro, Isabela, Aznar, Christine, Britto, Constança, Yadón, Zaida Estela, Schijman, Alejandro G

“…An international study was performed by 26 experienced PCR laboratories from 14 countries to assess the performance of duplex quantitative real-time PCR (qPCR)…”
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