Search Results - "BIRNER, Peter"

Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism by Riedl, Julia, Preusser, Matthias, Nazari, Pegah Mir Seyed, Posch, Florian, Panzer, Simon, Marosi, Christine, Birner, Peter, Thaler, Johannes, Brostjan, Christine, Lötsch, Daniela, Berger, Walter, Hainfellner, Johannes A., Pabinger, Ingrid, Ay, Cihan

“…Venous thromboembolism (VTE) is common in patients with brain tumors, and underlying mechanisms are unclear. We hypothesized that podoplanin, a sialomucin-like…”
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Tumor infiltrating lymphocytes and PD-L1 expression in brain metastases of small cell lung cancer (SCLC) by Berghoff, Anna Sophie, Ricken, Gerda, Wilhelm, Dorothee, Rajky, Orsolya, Widhalm, Georg, Dieckmann, Karin, Birner, Peter, Bartsch, Rupert, Preusser, Matthias

“…Brain metastases (BM) are frequent in small cell lung cancer (SCLC). Novel insights into their pathobiology are needed for development of better therapies. We…”
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High correlation of temporal muscle thickness with lumbar skeletal muscle cross-sectional area in patients with brain metastases by Leitner, Johannes, Pelster, Sebastian, Schöpf, Veronika, Berghoff, Anna S, Woitek, Ramona, Asenbaum, Ulrika, Nenning, Karl-Heinz, Widhalm, Georg, Kiesel, Barbara, Gatterbauer, Brigitte, Dieckmann, Karin, Birner, Peter, Prayer, Daniela, Preusser, Matthias, Furtner, Julia

“…This study aimed to assess the correlation of temporal muscle thickness (TMT), measured on routine cranial magnetic resonance (MR) images, with lumbar skeletal…”
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Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma by Koperek, Oskar, Kornauth, Christoph, Capper, David, Berghoff, Anna Sophie, Asari, Reza, Niederle, Bruno, von Deimling, Andreas, Birner, Peter, Preusser, Matthias

“…The V600E mutation of the B-type Raf kinase (BRAF) gene is a common event in papillary thyroid carcinoma (PTC) and seems to play a key role in the development…”
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Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis by Proestling, Katharina, Birner, Peter, Gamperl, Susanne, Nirtl, Nadine, Marton, Erika, Yerlikaya, Gülen, Wenzl, Rene, Streubel, Berthold, Husslein, Heinrich

“…Epithelial to mesenchymal transition (EMT) is a process in which epithelial cells lose polarity and cell-to-cell contacts and acquire the migratory and…”
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Tumor-infiltrating lymphocyte subsets and tertiary lymphoid structures in pulmonary metastases from colorectal cancer by Schweiger, Thomas, Berghoff, Anna Sophie, Glogner, Christoph, Glueck, Olaf, Rajky, Orsolya, Traxler, Denise, Birner, Peter, Preusser, Matthias, Klepetko, Walter, Hoetzenecker, Konrad

“…The presence of tumor-infiltrating lymphocytes (TILs) and tertiary lymphoid structures (TLSs) reflects an active inflammatory tumor microenvironment. High…”
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Screening for oncogenic AF1q expression predicts disease recurrence in gastric cancer patients by Gruber, Elisabeth S., Oberhuber, Georg, Schlederer, Michaela, Birner, Peter, Jomrich, Gerd, Schoppmann, Sebastian F., Tse, William, Kenner, Lukas

“…AF1q associates with tumor progression and metastases upon WNT signaling. The downstream WNT target CD44 has demonstrated prognostic significance in gastric…”
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STAT3 tyrosine phosphorylation influences survival in glioblastoma by Birner, Peter, Toumangelova-Uzeir, Kalina, Natchev, Sevdalin, Guentchev, Marin

“…Signal transducer and activator of transcription protein 3 (STAT3) is a regulator of central nervous system (CNS) development and a promising therapeutic…”
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Quantitative evidence for early metastatic seeding in colorectal cancer by Hu, Zheng, Ding, Jie, Ma, Zhicheng, Sun, Ruping, Seoane, Jose A., Scott Shaffer, J., Suarez, Carlos J., Berghoff, Anna S., Cremolini, Chiara, Falcone, Alfredo, Loupakis, Fotios, Birner, Peter, Preusser, Matthias, Lenz, Heinz-Josef, Curtis, Christina

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Lymphovascular invasion of tumor cells in lymph node metastases has a negative impact on survival in esophageal cancer by Schiefer, Ana-Iris, MD, Schoppmann, Sebastian F., MD, Birner, Peter, MD, MSc

“…Background Lymph node metastases constitute a strong prognostic factor in esophageal cancer. Nevertheless, the mechanisms and relevance of further spread of…”
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PD1 (CD279) and PD-L1 (CD274, B7H1) expression in primary central nervous system lymphomas (PCNSL) by Berghoff, Anna Sophie, Ricken, Gerda, Widhalm, Georg, Rajky, Orsolya, Hainfellner, Johannes A, Birner, Peter, Raderer, Markus, Preusser, Matthias

“…Primary central nervous system lymphoma (PCNSL) is a malignant brain tumor with limited treatment options and shows prominent infiltration by tumor…”
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Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E by Mesteri, Ildiko, Bayer, Günther, Meyer, Jochen, Capper, David, Schoppmann, Sebastian F, von Deimling, Andreas, Birner, Peter

“…BRAF V600E mutation in serrated lesions of the colon has been implicated as an important mutation and as a specific marker for the serrated carcinogenic…”
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Mutant IDH1 inhibits PI3K/Akt signaling in human glioma by Birner, Peter, Pusch, Stefan, Christov, Christo, Mihaylova, Stiliana, Toumangelova‐Uzeir, Kalina, Natchev, Sevdalin, Schoppmann, Sebastian F., Tchorbanov, Andrey, Streubel, Berthold, Tuettenberg, Jochen, Guentchev, Marin

“…BACKGROUND Recently, isocitrate dehydrogenase 1 (IDH1) was identified as a major participant in glioma pathogenesis. At present, the enzymatic activity of the…”
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Apigenin and Luteolin Attenuate the Breaching of MDA-MB231 Breast Cancer Spheroids Through the Lymph Endothelial Barrier in Vitro by Hong, Junli, Fristiohady, Adryan, Nguyen, Chi H, Milovanovic, Daniela, Huttary, Nicole, Krieger, Sigurd, Hong, Junqiang, Geleff, Silvana, Birner, Peter, Jäger, Walter, Özmen, Ali, Krenn, Liselotte, Krupitza, Georg

“…Flavonoids, present in fruits, vegetables and traditional medicinal plants, show anticancer effects in experimental systems and are reportedly non-toxic. This…”
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EGFR, BRAF and KRAS Status in Patients Undergoing Pulmonary Metastasectomy from Primary Colorectal Carcinoma: A Prospective Follow-Up Study by Schweiger, Thomas, Hegedüs, Balazs, Nikolowsky, Christoph, Hegedüs, Zita, Szirtes, Ildiko, Mair, Roland, Birner, Peter, Döme, Balazs, Lang, György, Klepetko, Walter, Ankersmit, Hendrik Jan, Hoetzenecker, Konrad

“…Background Pulmonary metastasectomy is an integral part of the interdisciplinary treatment of patients with pulmonary metastases (PMs) from colorectal…”
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Tumor-Associated Macrophages Express Lymphatic Endothelial Growth Factors and Are Related to Peritumoral Lymphangiogenesis by Schoppmann, Sebastian F., Birner, Peter, Stöckl, Johannes, Kalt, Romana, Ullrich, Robert, Caucig, Carola, Kriehuber, Ernst, Nagy, Katalin, Alitalo, Kari, Kerjaschki, Dontscho

“…Formation of lymphatic metastasis is the initial step of generalized spreading of tumor cells and predicts poor clinical prognosis. Lymphatic vessels generally…”
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Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients by Proestling, Katharina, Birner, Peter, Balendran, Sukirthini, Nirtl, Nadine, Marton, Erika, Yerlikaya, Gülen, Kuessel, Lorenz, Reischer, Theresa, Wenzl, Rene, Streubel, Berthold, Husslein, Heinrich

“…Current evidence suggests that endometrial-derived stem cells, spilled in the peritoneal cavity via retrograde menstruation, are key players in the…”
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Stromal expression of heat-shock protein 27 is associated with worse clinical outcome in patients with colorectal cancer lung metastases by Schweiger, Thomas, Nikolowsky, Christoph, Starlinger, Patrick, Traxler, Denise, Zimmermann, Matthias, Birner, Peter, Hegedüs, Balazs, Dome, Balazs, Bergmann, Michael, Mildner, Michael, Klepetko, Walter, Hoetzenecker, Konrad, Ankersmit, Hendrik Jan

“…Pulmonary metastases are common in patients with primary colorectal cancer (CRC). Heat-shock protein 27 (Hsp27) is upregulated in activated fibroblasts during…”
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Preoperative diffusion-weighted imaging of single brain metastases correlates with patient survival times by Berghoff, Anna Sophie, Spanberger, Thomas, Ilhan-Mutlu, Aysegül, Magerle, Manuel, Hutterer, Markus, Woehrer, Adelheid, Hackl, Monika, Widhalm, Georg, Dieckmann, Karin, Marosi, Christine, Birner, Peter, Prayer, Daniela, Preusser, Matthias

“…MRI-based diffusion-weighted imaging (DWI) visualizes the local differences in water diffusion in vivo. The prognostic value of DWI signal intensities on the…”
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Co-overexpression of HER2/HER3 is a predictor of impaired survival in breast cancer patients by Berghoff, Anna S, Bartsch, Rupert, Preusser, Matthias, Ricken, Gerda, Steger, Guenther G, Bago-Horvath, Zsuzsanna, Rudas, Margareta, Streubel, Berthold, Dubsky, Peter, Gnant, Michael, Fitzal, Florian, Zielinski, Christoph C, Birner, Peter

“…Abstract Background Recently, HER3-expression was postulated as independent risk factor for metastatic spread. Therefore, we investigated the role of HER3…”
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